ABSORPTION OF FUCOIDAN6- Fucoidan digestive enzymes including amylase, protease and lipase are attached to the plasma membrane.https://brainbarriers4you.eu/paracellular_v_transcell_en.ht
NONG LAM UNIVERSITY HO CHI MINH CITY FACULTY OF BIOLOGICAL SCIENCES DIGESTION AND ABSORPTION OF FUCOIDAN Group | Presentation Ho Chi Minh City, April 6, 2023 MEMBER LIST Nguyen Lan Anh 21126009 Do Ngoc Bao Chan 21126287 Nguyen Thi Lan Anh 21126014 Pham Thi My Hanh 21126054 Huynh Ngoc Thuy Duong 21126037 Le Hoang Phuc 21126162 TOPIC OUTLINE What is Fucoidan? The components of Fucoidan Absorption of Fucoidan Practical application research By Holly Monery, examiner.com.au Conclusion By Holly Monery, examiner.com.au WHAT IS FUCOIDAN? Fucoidan Cell wall polysaccharides found meicreatesherworld.blogspot.com in various species of brown seaweeds Fucose-containing sulfated polysaccharides comprise 5–20% The algal dry weight (FCSPs) By Robert Seeman, a blog about natural medicine THE COMPONENTS OF FUCOIDAN - Is a bioactive compound with high molecular weight - Fucoidan extracts contain fucose, galactose, xylose, mannose, and glucose An unusual sugar Fucose Present in a variety of glycolipids and glycoproteins Produced by mammalian cell ABSORPTION OF FUCOIDAN - Fucoidan digestive enzymes including amylase, protease and lipase are attached to the plasma membrane - Fucoidan can pass the intestinal barrier through two parallel routes; https://brainbarriers4you.eu/paracellular_v_transcell_en.html trasnscellular and paracellular - These compounds infiltrate enterocytes by active transport via Na+ - dependent glucose transporters https://www.inspiritvr.com/ap-bio/unit-2/mechanisms-of-transport-study-guide ABSORPTION OF FUCOIDAN - The transported nutrients from fucoidan as energy sources could enhance intestinal barrier integrity and maintain intestinal homeostasis by interacting with - But the permeation various intestinal cells of high molecular weight polysaccharides, such as fucoidan, through the paracellular pathway was previously shown to be restricted by tight junctions PRACTICAL APPLICATION RESEARCH (1) A study on newly weaned pigs that fucoidan-supplemented diets significantly increased intestinal villous height Fucoidan can improve the intestinal health of animals by modulating intestinal morphology https://www.thethings.com/photos-pictures-prove-teacup-pig-cutest-pet-adorable-piglet/#care-for-a-cuppa PRACTICAL APPLICATION RESEARCH (2) In another study using pigs diets containing laminarin and fucoidan Increased the coefficient of total tract apparent digestibility https://www.pigadvocates.com/pig-nutrition.html Decreased counts of Escherichia coli in the feces PRACTICAL APPLICATION RESEARCH (3) In a study using a dextran sulfate sodium salt mouse model of acute colitis Mice fed with fucoidan extracts + Significant reduction in diarrhea and fecal showed blood + Decreased the infiltration of inflammatory cell https://www.nature.com/articles/d41586-018-05694-w CONCLUSION Dietary fucoidan enhance gut immune functions through immunomodulatory and antiinflammatory WORK ASSIGNMENT Nguyen Lan Anh Making powerpoint Nguyen Thi Lan Do theAnh compilation Huynh Ngoc Thuy Duong Making content Do Ngoc Bao Chan Pham Thi My Hanh Le Hoang Phuc Making content Making content Report section THANK YOU FOR LISTENING! Don't hesitate to ask any questions!