Molecular Diagnostics (Phân tích nhanh chất lượng thực phẩm)

Molecular Diagnostics PhD. Hoa Quang LE School of Biotechnology and Food Technology Hanoi University of Science and Technology Some success stories Glucose sensor → Diabetic patients can monitor blood glucose at home Glucose sensor Pregnancy testing Pregnancy testing  Human chorionic gonadotropin (hCG) is a glycopeptide hormone produced by the placenta during pregnancy.  The appearance and rapid rise in the concentration of hCG in the woman's urine makes it a good pregnancy marker.  Usually, concentration of hCG in urine is at least 25 mIU/ml as early as seven to ten days after conception.  The concentration increases steadily and reaches its maximum between the eighth and eleventh weeks of pregnancy. Pregnancy testing Molecular diagnostics  Diagnosis of infectious diseases  Diagnosis of genetic diseases  Genetic identification Characteristics of a detection system  A good detection system should at least have 3 qualities: • Sensitivity • Specificity • Simplicity  Sensitivity means that the test must be able to detect very small amounts of target even in the presence of other molecules.  Specificity: the test yields a positive result for the target molecule only.  Simplicity: the test must be able to run efficiently and inexpensively on a routine basis. Diagnosis of infectious diseases  Viruses (HIV, HBV, HCV…)  Bacteria (Vibrio cholerae, Mycobacterium tuberculosis…)  Fungi (Aspergillus, Candida) . Molecular Diagnostics PhD. Hoa Quang LE School of Biotechnology and Food Technology Hanoi University. reaches its maximum between the eighth and eleventh weeks of pregnancy. Pregnancy testing Molecular diagnostics  Diagnosis of infectious diseases  Diagnosis of genetic diseases  Genetic