genetics principles and analysis - daniel l. hartl

[...]... Four-Strand Stage of Meiosis 134 The Molecular Basis of Crossing-over 137 Multiple Crossing-over 138 4-3 Gene Mapping from Three-Point Testcrosses 141 Chromosome Interference in Double Crossing-over 143 Genetic Mapping Functions 144 Genetic Distance and Physical Distance 145 4-4 Genetic Mapping in Human Pedigrees 146 4-5 Mapping by Tetrad Analysis 150 The Analysis of Unordered Tetrads 151 The Analysis. .. Development and Intercellular Signaling 514 Early Development and Activation of the Zygote Genome 518 Composition and Organization of Oocytes 518 1 2-3 Genetic Control of Cell Lineages 519 Genetic Analysis of Development in the Nematode 520 Mutations That Affect Cell Lineages 522 Types of Lineage Mutations 522 The lin-12 Developmental-Control Gene 526 1 2-4 Development in Drosophila 529 Maternal-Effect Genes and. .. 1 5-1 Allele Frequencies and Genotype Frequencies 628 Allele Frequency Calculations 628 Enzyme Polymorphisms 629 DNA Polymorphisms 630 1 5-2 Systems of Mating 632 Random Mating and the Hardy-Weinberg Principle 634 Implications of the Hardy-Weinberg Principle 635 A Test for Random Mating 635 Frequency of Heterozygotes 637 Multiple Alleles 638 X-linked Genes 639 1 5-3 DNA Typing and Population Substructure... 312 8-4 Conjugation 314 Plasmids 314 Hfr Cells 317 Time-of-Entry Mapping 319 F' Plasmids 324 8-5 Transduction 325 8-6 Bacteriophage Genetics 329 Plaque Formation and Phage Mutants 330 Genetic Recombination in Virulent Bacteriophages 331 Fine Structure of the rII Gene in Bacteriophage T4 336 8-7 Genetic Recombination in Temperate Bacteriophages 340 Lysogeny 340 Specialized Transducing Phage 345 8-8 Transposable... host-range and plaque-type mutants of bacteriophage in single bacterial cells 329 Connection: Artoo Seymour Benzer 1955 Fine structure of a genetic region in bacteriophage 334 GeNETics on the Web 354 Page viii Chapter 9 Genetic Engineering and Genome Analysis 9-1 Restriction Enzymes and Vectors 358 360 Production of Defined DNA Fragments 360 Recombinant DNA Molecules 362 Plasmid, Lambda, Cosmid, and. .. Unequal Crossing-Over in Human Red-Green Color Blindness 283 Inversions 286 Reciprocal Translocations 288 Robertsonian Translocations 293 7-7 Position Effects on Gene Expression 296 7-8 Chromosome Abnormalities and Cancer 297 Retinoblastoma and Tumor-Suppressor Genes 298 Chapter End Material Chapter Summary 300 Key Terms 300 Review the Basics 301 Guide to Problem Solving 301 Analysis and Applications... Marthe Gautier, and Raymond Turpin 1959 Study of the somatic chromosomes of nine Down syndrome children 271 Connection: Lyonization of an X Chromosome Mary F Lyon 1961 Gene action in the X chromosome of the mouse (Mus musculus L.) 276 GeNETics on the Web 303 Chapter 8 The Genetics of Bacteria and Viruses 306 8-1 The Genetic Organization of Bacteria and Viruses 308 8-2 Bacterial Mutants 311 8-3 Bacterial... Connection: The White-Eyed Male Thomas Hunt Morgan 1910 Sex limited inheritance in Drosophila 101 Connection: The Case Against Mendel's Gardener Ronald Aylmer Fisher 1936 Has Mendel's work been rediscovered? 112 GeNETics on the Web 118 Chapter 4 Genetic Linkage and Chromosome Mapping 122 4-1 Linkage and Recombination of Genes in a Chromosome 124 4-2 Genetic Mapping 127 Crossing-over 132 Crossing-over Takes... Lambda, Cosmid, and P1 Vectors 365 9-2 Cloning Strategies 365 Joining DNA Fragments 366 Insertion of a Particular DNA Molecule into a Vector 366 The Use of Reverse Transcriptase: cDNA and RT-PCR 369 Detection of Recombinant Molecules 370 Screening for Particular Recombinants 372 Positional Cloning 372 9-3 Site-Directed Mutagenesis 374 9-4 Reverse Genetics 377 Germ-Line Transformation in Animals 377... Viable offspring derived from fetal and adult mammalian cells 380 Connection: YAC-ity YAC David T Burke, Georges F Carle and Maynard V Olson 1987 Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors 393 GeNETics on the Web 408 Chapter 10 Gene Expression 410 1 0-1 Proteins and Amino Acids 412 1 0-2 Relations between Genes and Polypeptides 415 What Are the Minimal . Manufacture: World Color Book Services Library of Congress Cataloging-in-Publication Data Hartl, Daniel L. Genetics: Principles and analysis / Daniel L. Hartl, Elizabeth W. Jones.—4th ed. p. cm. Includes.