AI for Medical imaging Name Course Master Student ID Dataset BrainTumor 1 Introduction The main task of this project Binary Classification Predict the MGMT methylation status using MRI from patients with brain tumor 1 1 What is the MGMT? Glioblastoma is the most frequent malignant primary tumor in the brain It has a very poor prognosis, with a median survival of less than a year The current standard if care consists of surgical resection followed by radiotherapy in addition to alkylating chemoth.
AI for Medical imaging Name Course Master Student ID Dataset BrainTumor Introduction The main task of this project: Binary Classification Predict the MGMT methylation status using MRI from patients with brain tumor 1.1 What is the MGMT? Glioblastoma is the most frequent malignant primary tumor in the brain It has a very poor prognosis, with a median survival of less than a year The current standard if care consists of surgical resection followed by radiotherapy in addition to alkylating chemotherapy with temozolomide MGMT (O[6]-methylguanine – DNA methyltransferase) is a DNA repair enzyme This enzyme rescues tumor cells from alkylating agent-induced damage, leading to chemotherapy resistance with alkylating agents 1.2 MRI and MGMT Connection MGMT promotor methylated glioblastoma is likely to show less aggressive imaging feature than MGMT promotor unmethylated glioblastoma Datasets Dataset link: https://1drv.ms/u/s!AsG5zlY5lnaKtMdjgnkybLzavG19iw? e=BPWmBu Data Description Format Patients in training sets Patients in testing sets DICOM 400 185 There are sub-folders, each of them corresponding to each of the MRI scans, in DICOM format, included: + Fluid Attenuated Inversion Recovery (Flair) + T1 – weighted pre – contrast (T1w) + T2 – weighted contrast enhanced (T1CE) + T2 – weighted (T2) The dataset structure: Train/Test/Validation | _00000 | | _FLAIR | | |Image-1.dcm | | |Image-2.dcm | | |… | | _T1w | | |Image-1.dcm | | |Image-2.dcm | | |… | | _T1wCE | | |Image-1.dcm | | |Image-2.dcm | | |… | | _T2w | | |Image-1.dcm | | |Image-2.dcm | | |… train/ folder: contain the training files labels.csv: contain the target MGMT_value for each subject in the training data test/ folder: contain the testing files Figure : The bar graph for labels.csv file Figure 2: The bar graph for train data Figure 3: The pie chart for labels.csv In this project, the sub-folders FLAIR and T1wCE were used Method The workflow: Input image (Dcm file) Convert to gray Support Vector Machines Result Support-vector machines (SVMs) are supervised learning models with associated learning algorithms that analyze data for classification and regression analysis SVC is a similar method that also builds on kernel functions but is appropriate for unsupervised learning I use class sklearn.svm.SVC Results For training: The mean accuracy: For validation: For testing: The probability of each patient was saved in submission_c1.csv Classification result for test data Conclusion + The result was generate and it is not good + In the future, I need to apply the deep learning method in this problem to improve the accuracy + Limitation: The time of semester is limited # Bổ sung thêm code ... gray Support Vector Machines Result Support-vector machines (SVMs) are supervised learning models with associated learning algorithms that analyze data for classification and regression analysis... learning I use class sklearn.svm.SVC Results For training: The mean accuracy: For validation: For testing: The probability of each patient was saved in submission_c1.csv Classification result for... was generate and it is not good + In the future, I need to apply the deep learning method in this problem to improve the accuracy + Limitation: The time of semester is limited # Bổ sung thêm