Cell Cycle Regulation in Mammalian Germ Cells

... Probl Cell Differ (42) P. Kaldis: Cell Cycle Regulation DOI 10.1007/003/Published online: 20 December 2005 © Springer-Verlag Berlin Heidelberg 2005 Cell Cycle Regulation in Mammalian Germ Cells Changanamkandath ... However, understanding cell cycle regulation in mammalian germ cells has considerably lagged behind that of the mitotic cell cycle. Challenge...

Ngày tải lên: 25/10/2013, 21:20

... 81:323–330 Welch PJ, Wang JY (1993) A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle. Cell 75:779–790 Wells J, Boyd KE, Fry ... overlapping roles in controlling cell cycle exit upon growth-inhibiting signals. Only ablation of all pocket proteins fully alleviated a cell cycle arrest upon serum withdra...

Ngày tải lên: 25/10/2013, 21:20

... Kaldis: Cell Cycle Regulation DOI 10.1007/b138827/Published online: 23 September 2005 © Springer-Verlag Berlin Heidelberg 2005 Protein Kinases Involved in Mitotic Spindle Checkpoint Regulation Ingrid ... Rec8, vimentin, desmin, the kinesin MCAK, histone H3 Aurora C Protein kinase, binds to INCENP and Aurora B MAPK Protein kinase Rod Identified in Drosophila, binds to Zw10 Zw10 Iden...

Ngày tải lên: 07/10/2012, 16:51

... HeLa cell cycle in a site-specific manner. Cyclin-dependent protein kinase is involved in the phosphorylation of MCM4 To determine which kinase is involved in the phos- phorylation of MCM4 in phases ... named mitotic (M) cells. Residual cells were collected and named G 2 cells. These cells and logarithmically grow- ing cells were separated into Triton-soluble (S) and Trito...

Ngày tải lên: 16/03/2014, 13:20

... in the Cdc25C pro- moter by in vivo footprinting as being protected in G 0 cells. The Cdc25C gene is not expressed in resting cells or in cells in G 1 phase. Only in G 2 phase can strong transcription ... proteins with the promoter. E2F4 binding during the cell cycle coincides with the binding of p107 or p130 [61,85]. Another E2F site distal to the E2F ⁄ CDE acts as an...

Ngày tải lên: 16/02/2014, 09:20

... integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensing of glutamine-induced hepatocyte swelling by integrins feeds into ... stimuli in mammalian cells with some focus on the hepatocyte. A more general treatize on osmosensing and osmosignal- ing is provided elsewhere [9]. Osmosensing in mammalian cells The...

Ngày tải lên: 18/02/2014, 16:20

... below. REGULATION OF eEF2 AND eEF2 KINASE BY INSULIN AND OTHER STIMULI Redpath et al. [52] showed that, in Chinese hamster ovary (CHO) cells overexpressing the insulin receptor, insulin causes the rapid dephosphorylation ... may involve a glycine-rich motif, which would thus serve quite a different function in these kinases from the role of a similar motif in phosphate binding in...

Ngày tải lên: 23/03/2014, 21:20

... the epithelial cells of the gastro-intestinal tract are similar – if on different time scales. In the gastrointestinal tract of mammals the cell- cycle time of a particular cell is in the range 5–10 ... together at particular points in the cycle. This temporal organization extends to the synchronous gating of cells into the S phase. DNA replication in these cells begins ab...

Ngày tải lên: 30/03/2014, 04:20

... colony as a whole. An intriguing candidate is the lectin-like protein involved in flocculation, a cell wall protein that binds to mannose chains on the surface of other cells to provide the physical ... unity indicates the non-noisy character of the extracted modes, pointing to the highly coordinated gene expression behaviour of these cells. HeLa cells display whole genome cell cy...

Ngày tải lên: 30/03/2014, 08:20