Intravesical tumor necrosis factor alpha gene therapy mediated by a novel liposome system in an orthotopic murine bladder cancer model

... RelA and p50 ⁄ NFjB1 nuclear < /b> factor-< /b> jB (NF-jB) subunits, and the jB-dependent transcription was also modulated by tumor necrosis factor < /b> alpha (TNF-a) p65 ⁄ p50 transcriptional modulation of Rnf33 ... in both the Leydig and Sertoli cells of the testis kb Rnf33TSS’s Rnf35 P1 Rnf33 Fig Map of the Rnf35 and Rnf33 genes The relative map position...

Ngày tải lên: 29/03/2014, 00:20

... in the human brain after fatal head injury J Neurotrauma 2002, 19:279-84 Macdonald NJ, Taglialatela G: Tumor necrosis factor alpha and nerve growth factor synergistically induce iNOS in pheochromocytoma ... Cuzzocrea S: Inhibition of the nuclear factor- kappaB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spin...

Ngày tải lên: 19/06/2014, 22:20

... coincident with the increase of TNF-α and MCP-1 We believe this could be due to microglial proliferation, activation of the resting resident population of brain microglia and macrophages and/ or recruitment ... entorhinal cortex and hippocampus of 3xTg-AD mice By months of age, 3xTg-AD mice exhibit further enhanced deposition of hAβ in both regions Panel B identifie...

Ngày tải lên: 19/06/2014, 22:20

... Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy Diana Spicarova, Vladimir Nerandzic and Jiri Palecek Department of Functional Morphology, ... Bhuskute A, Sorkin LS: Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal c...

Ngày tải lên: 19/06/2014, 22:20

... (du hiu Grey Turner) hoc quanh rn (du hiu Cullen) Nhng du hiu ny ớt gp nhng nu cú l biu hin chy m u vựng ty, quanh ty v l nhng du hiu nng Tỡnh trng sc thc s gp VTC nng v l hu qu ca nụn nhiu, ... nghiờn cu v cytokin ny VTC Vỡ vy chỳng tụi tin hnh ti Bc u nghiờn cu nng yu t hoi t u alpha TNF (Tumor Necrosis Factor -alpha) huyt bnh nhõn viờm ty cp, nhm hai mc ti u sau: Tỡm hiu n...

Ngày tải lên: 24/07/2014, 01:57

... aggrecan and type II collagen mRNA by TNF-α, by EGF or R132 tumor necrosis factor alpha (TNF-α) Epidermal growth factor (EGF) does not alter NF-κB activation by tumor necrosis factor alpha (TNF-α) ... necrosis factor alpha Inhibitionandprotein collagen mRNAnot prevent reduction in levels of aggrecan or type II collagen mRNA by tumor necrosis factor alpha...

Ngày tải lên: 09/08/2014, 06:22

... conceived the design of the study, coordinated all of the laboratorial work, personally observed most of the patients and coordinated and trained others to perform the same observations, coordinated and ... lip biopsy and/ or salivary scintigraphy) Simple x-rays of the hands and feet were analyzed with the Sharp/van der Heijde (SvdH) method [10] Disease activit...

Ngày tải lên: 09/08/2014, 10:20

... aggrecanase activity might be involved in the early TNFα -mediated aggrecanolysis in the meniscus Inhibition of aggrecanase activity or TNFα -activity might therefore help to prevent meniscal destruction ... proteoglycan degradation in cartilage tissues can be mediated by both the production of NO and the involvement of matrix-degrading enzymes We therefo...

Ngày tải lên: 09/08/2014, 14:22

... found in 3.7% of patients undergoing surgery for chronic inflammatory sinusitis [12] Sinus aspergilloma is often asymptomatic and may therefore be overlooked during the workup performed before ... Ankylosing spondylitis ? ? [43] Aspergilloma Lung Ankylosing spondylitis Radiation therapy Recovery [44] Aspergilloma Lung Ankylosing spondylitis ? Recovery [45] Aspergilloma Lung Anky...

Ngày tải lên: 09/08/2014, 14:22

... [23] We analyzed the association of smoking status (current smoking or no-smoking) and presence of disease (COPD) with systemic inflammation (TNF-α, IL-6, IL-8 and CRP) using a multiple linear regression ... levels of TNF-α, IL-6, IL-8, and CRP Discussion This study aimed to evaluate the relationship between systemic inflammation and smoking status in COPD patients The...

Ngày tải lên: 11/08/2014, 03:20

... Insulin augments tumor necrosis factor-alpha stimulated expression of vascular cell adhesion molecule-1 in vascular endothelial cells Daniel Z Mackesy1 and Marc L Goalstone1,2,* Department of ... pathogenesis of atherosclerosis by augmenting the effects of inflammatory cytokines, thereby significantly increasing the expression of CAMs [6-11] One such cyto...

Ngày tải lên: 11/08/2014, 03:20

... [23] We analyzed the association of smoking status (current smoking or no -smoking) and presence of disease (COPD) with systemic inflammation (TNF-α, IL-6, IL-8 and CRP) using a multiple linear regression ... levels of TNF-α, IL-6, IL-8, and CRP Discussion This study aimed to evaluate the relationship between systemic inflammation and smoking status in COPD patie...

Ngày tải lên: 11/08/2014, 06:22

... this article as: Arends et al.: Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational ... who are more likely to benefit from TNF -a blocking therapy in daily clinical practice Abbrevations AS: Ankylosing Spondylitis; ASAS: Assessment...

Ngày tải lên: 12/08/2014, 17:21

... Esuvaranathan K Intravesical liposome -mediated tumor necrosis factor- α gene therapy in an orthotopic murine bladder cancer model, (Oral Presentation and Travel Grant Award), 6th Annual Meeting ... Yong T, Esuvaranathan K Intravesical Liposomemediated Tumor Necrosis Factor- alpha gene therapy in an orthotopic murine bladder cancer model (...

Ngày tải lên: 08/11/2015, 16:45