tumor necrosis factor alpha tnf alpha

... tumor necrosis factoralpha in mouse spermatogenic cells Endocrinology 133, 389–396 33 Mauduit C, Gasnier F, Rey C, Chauvin MA, Stocco DM, Louisot P & Benahmed M (1998) Tumor necrosis factor- alpha ... the p65 ⁄ RelA and p50 ⁄ NFjB1 nuclear factor- jB (NF-jB) subunits, and the jB-dependent transcription was also modulated by tumor necrosis factor alpha (TNF- a) p65 ⁄ p50 transcriptional modulation ... of tumor necrosis factor- alpha in the regulation of mouse Leydig cell steroidogenesis Endocrinology 132, 2438–2444 35 Ziparo E, Riccioli A, Filippini A, De Cesaris P & Barbacci E (1995) TNF- alpha...

Ngày tải lên: 29/03/2014, 00:20

... partly based on observations of increased levels of the pro-inflammatory cytokines tumor necrosis factor alpha (TNF ) and interleukin-1 beta (IL-1β) in cerebrospinal fluid and brain cortex of AD ... secreted alkaline phosphatase; S.E.M, standard error of the mean; Strep, streptomycin; TNF , tumor necrosis factor alpha; TrkA, troponin-like receptor kinase A; TTBS, trisbuffered saline with tween ... fatal head injury J Neurotrauma 2002, 19:279-84 Macdonald NJ, Taglialatela G: Tumor necrosis factor alpha and nerve growth factor synergistically induce iNOS in pheochromocytoma cells Neuroreport...

Ngày tải lên: 19/06/2014, 22:20

... tumor necrosis factor alpha on the synthesis of Abeta1-40 and Abeta1-42 by human astrocytes Neurobiol Dis 2000, 7:682-689 Liao YF, Wang BJ, Cheng HT, Kuo LH, Wolfe MS: Tumor necrosis factor- alpha, ... APPswe: Amyloid precursor protein Swedish mutation PS1: Presenilin Aβ : Beta-amyloid TNF- α : Tumor necrosis factor- alpha Tg: Transgenic PBS: Phosphate-buffered saline Competing interests The author(s) ... 0.809 +/- 0.257 TNFR1 signaling can lead to diminished γ-secretase activity [32] Further evidence supporting pathogenic effects of TNF- α-mediated signaling is TNFR1 and TRADD, a TNF receptor adaptor...

Ngày tải lên: 19/06/2014, 22:20

... Schafer MK: Cell-specific expression and lipopolysaccharideinduced regulation of tumor necrosis factor alpha (TNFalpha) and TNF receptors in rat dorsal root ganglion J Neurosci 2004, 24:9623-9631 Hensellek ... Blumer MJ, Scherbakov N, Davis JB, Bluethmann H, Ji RR, Kress M: Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type to generate heat hyperalgesia in a mouse cancer model ... induced by tumor necrosis factor- alpha J Neurosci 2010, 30:12844-12855 Zhang H, Dougherty PM: Acute inhibition of signalling phenotype of spinal GABAergic neurons by tumour necrosis factor J Physiol...

Ngày tải lên: 19/06/2014, 22:20

... ca TNF( , nng TNF( huyt thanh, huyt tng bnh nhõn viờm ty cp cú v khụng cú bin chng [28], [57], [74] 1.9.2 c im TNF 1.9.2.1 Cu to ca TNF : H TNF cú loi l TNF v TNF, ú TNF c gi l lymphotoxin TNF ... nghiờn cu nng yu t hoi t u alpha TNF (Tumor Necrosis Factor- alpha) huyt bnh nhõn viờm ty cp, nhm hai mc tiờu sau: Tỡm hiu nng TNF huyt bnh nhõn VTC i chiu gia nng TNF vi mc nng nh ca VTC theo ... hoỏ ca TNF v trớ 6P21 ca chromosome 6, trung tõm ca phc hp ho hp mụ chớnh Cú dng th cm th (Receptor) i vi TNF l TNF RI (P 55) cú trng lng 55 KDa v TNF RII (P75) cú trng lng 75 KDa Cú dng TNF: ...

Ngày tải lên: 24/07/2014, 01:57

... R193 Arthritis Research & Therapy Vol No Granet et al Figure Figure Effect of IL-1β, tumor necrosis factor alpha (TNF- α) and IL-17 used alone and in combination on C-Jun translocation Rheumatoid ... picture TNF, tumor necrosis factor R194 The combination of the three cytokines was even more potent, leading to a synergistic effect on all of the TF translocations except for Egr-1 This IL-1β, TNF- α ... Available online http://arthritis-research.com/content/6/3/R190 Figure Effects of IL-1β, tumor necrosis factor alpha (TNF- α) and IL-17 used alone and in combination on c-jun mRNA expression After 12...

Ngày tải lên: 09/08/2014, 01:23

... II collagen mRNA by TNF- α, by EGF or R132 tumor necrosis factor alpha (TNF- α) Epidermal growth factor (EGF) does not alter NF-κB activation by tumor necrosis factor alpha (TNF- α) (a) Chondrocytes ... Bernier Figure Figure alpha (TNF- α) maintained in the presence of tumor necrosis factor Cell viability is and/or epidermal growth factor (EGF) alpha (TNF- α) and/or epidermal growth factor (EGF) Subconfluent ... individual factors and partially protected against the effect of TNF- α and EGF in combination (TNF- α) or epidermal growth factor (EGF) aggrecan of type II kinase C does by tumor necrosis factor alpha...

Ngày tải lên: 09/08/2014, 06:22

... to human tumor necrosis factor alpha (hTNFα) Page of 13 (page number not for citation purposes) Available online http://arthritis-research.com/content/8/6/R166 32 was reported to induce TNF in ... cells (293T) for 24 hours Left, relative expression of mouse tumor necrosis factor alpha (mTNFα), compared with βactin; right, secreted TNF protein level measured by ELISA (b) We generated hIL-32β ... antibodies to tumor necrosis factor alpha Arthritis Rheum 1993, 36:1681-1690 Mori L, Iselin S, De Libero G, Lesslauer W: Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type (TNFR1)IgG1-treated...

Ngày tải lên: 09/08/2014, 08:23

... (page number not for citation purposes) necrosis factor (TNF) α Mechanisms involved in the regulation of CD36 expression by tumor necrosis factor (TNF) α (a) TNF inhibits both basal and rosiglitazoneinduced ... et al Figure Figure and adalimumab Regulation of CD36 mRNA expression by tumor necrosis factor (TNF) α and adalimumab TNF decreases CD36 mRNA expression and adalimumab increases CD36 mRNA expression ... http://arthritis-research.com/content/9/2/R22 Figure Regulation of CD36 membrane expression by tumor necrosis factor (TNF) α and adalimumab (Ada) (a) TNF reduces the membrane expression of (Ada) CD36: time course Human...

Ngày tải lên: 09/08/2014, 10:20

... Gene polymorphisms at position -308 of the tumornecrosis -factor- alpha (TNF -alpha) in multiple sclerosis and its influence on the regulation of TNF -alpha production Neurosci Lett 1996, 215:75-78 ... the human tumor necrosis factor- α gene promoter Tissue Antigens 1998, 52:359-367 Brinkman BM, Zuijdeest D, Kaijzel EL, Breedveld FC, Verweij CL: Relevance of the tumor necrosis factor α (TNF ) -308 ... Lett 1996, 215:75-78 Wu WS, McClain KL: DNA polymorphisms and mutations of the tumor necrosis factor- alpha (TNF -alpha) promoter in Page of 10 (page number not for citation purposes) Arthritis...

Ngày tải lên: 09/08/2014, 10:20

... Multiple roles for tumor necrosis factor- alpha and lymphotoxin alpha/ beta in immunity and autoimmunity Arthritis Res 2002, 4:S141-S152 Mageed RA, Isenberg DA: Tumour necrosis factor alpha in systemic ... http://arthritis-research.com/content/10/1/202 Table Tumor necrosis factor (TNF) expression and effects of recombinant TNF administration or TNF blockade in murine models of systemic lupus erythematosus Model [Reference] TNF expression ... Tumour necrosis factor- alpha in murine autoimmune ‘lupus’ nephritis Nature 1988, 331:356-358 10 Gordon C, Ranges GE, Greenspan JS, Wofsy D: Chronic therapy with recombinant tumor necrosis factor- alpha...

Ngày tải lên: 09/08/2014, 10:22

... availability, 21 of the 71 TNF- α-naïve AS patients were excluded from VEGF analysis Materials and methods Tumor necrosis factor- alpha blocker-naïve patients In the era before TNF- α-blocking treatment, ... VEGF, MMP-3, and BALP during tumor necrosis factor- alpha blocker treatment with adalimumab The majority of patients with axial SpA reported a major benefit from TNF- α therapy with adalimumab ... serum and years in a tumor necrosis factor- alpha metalloproteinase-3 of ankylosing bone-specific alkaline phosphatase (BALP) at baseline and after levels of vasoendothelial growth factor (VEGF), blocker-naïve...

Ngày tải lên: 09/08/2014, 13:22

... FA van de, Joosten LA, van Lent PL, Arntz OJ, Berg WB van den: Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction Effect ... integrative repair of the porcine meniscus in vitro by inhibition of interleukin-1 or tumor necrosis factor alpha Arthritis Rheum 2007, 56:3033-3042 Wilusz RE, Weinberg JB, Guilak F, McNulty AL: ... LeGrand A, Fermor B, Fink C, Pisetsky DS, Weinberg JB, Vail TP, Guilak F: Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin...

Ngày tải lên: 09/08/2014, 14:22

... associated with tumor necrosis factor antagonists Clin Infect Dis 2004, 38:1261-1265 Gardam MA, Keystone EC, Menzies R, Manners S, Skamene E, Long R, Vinh DC: Anti-tumour necrosis factor agents ... with RA treated with TNF blockers Ann Rheum Dis 2003, 62:791 Letter Tsiodras S, Samonis G, Boumpas DT, Kontoyiannis DP: Fungal infections complicating tumor necrosis factor alpha blockade therapy ... U, Craven DE: Invasive pulmonary aspergillosis soon after therapy with infliximab, a tumor necrosis factor- alpha- neutralizing antibody: a possible healthcare-associated case? Infect Control Hosp...

Ngày tải lên: 09/08/2014, 14:22

... (0.62-2.00) 1.07 (0.56-2.54) 4.65 (1.62-7.92) ‡† 6.85(2.97-9.39)‡† TNF- α(pg/mL) COPD current smokers N = 24 TNF- α :Tumor necrosis factor alpha, IL-6: interleukin 6, IL-8: interleukin 8, CRP: C-reative ... concentration of soluble TNF receptors (sTNF-R55 and sTNF-R75) [16] Although the TNF receptors are considered to be markers of a proinflammatory state inducible by cytokines such as TNF- α, they present ... (-21.129,12.888) SpO2 (%) 1.205 (-0.842,3.254) FFM (kg) 0.831 (-2.633,0.799) TNF- α: tumor necrosis factor- alpha; IL-6: interleukin 6; IL-8: interleukin 8; CRP: C-reactive protein; SpO2: peripheral...

Ngày tải lên: 11/08/2014, 03:20

... T: Tumor necrosis factor- alpha in sera of obese patients: fall with weight loss J Clin Endocrinol Metab 1998, 83:2907-2910 FIGURE LEGENDS: Figure – Insulin and Tumor Necrosis Factor- alpha (TNF ) ... One such cytokine is tumor necrosis factor- alpha (TNF ) TNF is secreted by mature macrophages and endothelial cells during the progression of atherosclerosis Interestingly, TNF activity is linked ... (insulin or TNF with no inhibitor) #, P < 0.05 vs insulin plus TNF (no inhibitors) (SFM) serum-free medium; (INHB) inhibitors; (NI) no inhibitors; (INS) insulin; (TNF ) Tumor Necrosis Factor- alpha; ...

Ngày tải lên: 11/08/2014, 03:20

... (0.62-2.00) 1.07 (0.56-2.54) 4.65 (1.62-7.92) ‡† 6.85(2.97-9.39)‡† TNF- α(pg/mL) COPD current smokers N = 24 TNF- α :Tumor necrosis factor alpha, IL-6: interleukin 6, IL-8: interleukin 8, CRP: C-reative ... concentration of soluble TNF receptors (sTNF-R55 and sTNF-R75) [16] Although the TNF receptors are considered to be markers of a proinflammatory state inducible by cytokines such as TNF- α, they present ... (-21.129,12.888) SpO2 (%) 1.205 (-0.842,3.254) FFM (kg) 0.831 (-2.633,0.799) TNF- α: tumor necrosis factor- alpha; IL-6: interleukin 6; IL-8: interleukin 8; CRP: C-reactive protein; SpO2: peripheral...

Ngày tải lên: 11/08/2014, 06:22

... D status; Lo-D: low vitamin D status; IL-6: interleukin-6; IL-10: interleukin 10; TNF- α: tumor necrosis factor- alpha 14 Competing interests 17 15 16 The authors declare that they have no competing ... Saito K, Furuya D, Yagihashi A, Araake H, Tsuji N, Sakamaki S, Niitsu Y, Watanabe N: Tumor necrosis factor- alpha in serum of patients with inflammatory bowel disease as measured by a highly sensitive ... 47:1297-1301 Koller-Strametz J, Pacher R, Frey B, Kos T, Woloszczuk W, Stanek B: Circulating tumor necrosis factor- alpha levels in chronic heart failure: relation to its soluble receptor II, interleukin-6,...

Ngày tải lên: 11/08/2014, 08:22

... or immunostained with antibodies against tumor necrosis factor- alpha converting enzyme (c, e), matrix metalloproteinase-3 (d, f), tumor necrosis factor- alpha (g), or CD68 (h) Note that hyperplastic ... with lymphoid nodules similar to rheumatoid arthritis (b), and tumor necrosis factor- alpha converting enzyme, tumor necrosis factor- alpha and matrix metalloproteinase-3 are expressed in synovial ... related to their suppressive effect on tumor necrosis factor- alpha (TNF- a) [2] Moreover, some authors have reported the effectiveness of new DMARDs, anti -TNF- a agents, especially for osteoarticular...

Ngày tải lên: 11/08/2014, 14:21