... sensitivity of cells to inhibition of protein synthesis by TRAIL We have previously shown that protein synthesis is rapidly downregulated following exposure of cells to TRAIL and other inducers of apoptosis ... able to decrease the inhibition of protein synthesis by TRAIL by 80% (Fig 2A) and, conversely, IFNa enhanced the sensitivity of protein s...
Ngày tải lên: 19/02/2014, 06:20
... recommendation of their program adviser or the approval of the associate dean of graduate studies in the School of Business Administration Master of International Management The Master of International ... Mktg 452 Business- to -Business Marketing (3) Other electives as approved by supply and logistics faculty Total 21-24 Requirements for minor in business adminis...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: Endogenous tetrahydroisoquinolines associated with Parkinson’s disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines doc
... TH inhibition Similar to the kinetics of TH inhibition by catecholamines [10,39], enzyme inhibition by NMNorsal is competitive with respect to the tetrahydropterin cofactor and noncompetitive with ... conformation of TH [33] We therefore compared the thermostability of hTH at 37 °C in the presence of NMNorsal, Norsal and DA In the absence of these ligands,...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris ppt
... removed by the yeast KEX2 protease (Pichia pastoris Expression Kit manual, Invitrogen, Groningen, the Netherlands) Cloning of elan and trappin-2 cDNA into pPIC9 Using the trappin-2 cDNA cloned into ... Measurement of kass and kdiss for the interaction of rec-elan or rec-trappin-2 with HNE and PR3 Linear inhibition curves were obtained when reacting increasing amount...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: A new and efficient method for inhibition of RNA viruses by DNA interference pptx
... and antisense strand (5¢-ATGAGTTTTCCAGAGCAACTT-3¢), and siRNA was synthesized using DNA templates (sense strand, 5¢-AAATGAGTTTTCCAGAGCAACCCTGTCTC-3¢; antisense strand, 5¢-AAGTTGCTCTGGAAAACTCATCCTG ... TTCTGGCCTTC-3¢, and that of s -DNA is 5¢-ATAGGCG GGAATTTTGCATC-3¢ Anti-TMV siRNA was synthesized using the DNA templates 5¢-AAGGGACGAGCA TATGTACACCCTGTCTC-3¢ and 5¢-AAGTGTACATAT G...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo Y học: Growth inhibition of mammalian cells by eosinophil cationic protein pptx
... induced by the eosinophil cationic protein and eosinophil protein X J Allergy Clin Immunol 70, 361±366 Motojima, S., Frigas, E., Loegering, D.A & Gleich, G.J (1989) Toxicity of eosinophil cationic proteins ... effect of growth inhibition may be replicated by other polycations To investigate this, we checked the effect of poly(L-lysine), which has a cationic charg...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion pptx
... enzyme BTC concentrations are: 50 lM, 200 lM, mM and mM Fig Progress curves for the hydrolysis of butyrylthiocholine catalyzed by the horse butyrylcholinesterase, by the W82A mutant of human butyrylcholinesterase ... Activation inhibition of human butyrylcholinesterase (Eur J Biochem 269) 1161 moities of tyrosine 133 and of the anionic subsite tryptophane 86 to catalyti...
Ngày tải lên: 24/03/2014, 03:21
báo cáo hóa học:" The integrated care pathway reduced the number of hospital days by half: a prospective comparative study of patients with acute hip fracture" doc
... to the patient motivation, the care of patients with a hip fracture requires a team approach in which the co-ordination between the various aspects of care is important Integrated care pathways ... further research [17] The aim of the present study was to evaluate the effectiveness of an ICP in patients with an acute fracture of the hip T...
Ngày tải lên: 20/06/2014, 00:20
Báo cáo y học: " Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos" pptx
... Lu et al.: Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos Journal of Biomedical Science 2011 18:73 Submit your next ... proliferation in vitro [30] Our results revealed tbx5 insufficiency ultimately resulted in activation of apoptosis and inhibition of cell growth...
Ngày tải lên: 10/08/2014, 10:20
báo cáo khoa học: " Inhibition of telomerase activity by HDV ribozyme in cancers" ppsx
... a portion of hTR component containing a telomeric template element using RT-PCR In normal conditions, only inhibition of the template region can lead to the inhibition of telomerase activity we ... some role in apoptosis-controlling mechanisms and inhibition of telomerase by ribozyme might impair this pathway wound healing in transgenic mice overexpressing the ca...
Ngày tải lên: 10/08/2014, 10:20
báo cáo khoa học: " Individual determinants of research utilization by nurses: a systematic review update" pot
... their research training, research needs and of their use of research in clinical areas Journal of Advanced Nursing 1999, 29(1):237-245 36 Parahoo K, McCaughan EM: Research utilization among medical ... outcome of interest, research utilization By this we mean that we observed a lack of standard measures of research utilization across studies While a few ins...
Ngày tải lên: 10/08/2014, 10:23
Báo cáo y học: "Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation" pps
... by this finding, as there are many promising anti-inflammatory and anti-bacterial ethnopharmacological agents that have not been adequately studied in the context of diseases that are atypical ... Gunaherath GM, Shirahatti N, Mahadevan D, Gunatilaka AA, Whitesell L: Actin microfilament aggregation induced by withaferin A is mediated by annexin II Nat Chem Biol 2006, 2:33-38 Ja...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: "Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon a" pptx
... the inhibition of MxA gene transcription by WT HBc or its hot-spot mutants has no impact on inhibition of HBV replication by IFN-a, indicating MxA may be independent of inhibition of HBV DNA replication ... Hepatitis B virus core protein with hotspot mutations inhibit MxA gene transcription but has no effect on inhibition...
Ngày tải lên: 12/08/2014, 01:22
Báo cáo y học: " Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome" pps
... HIV-1 by the hairpin- containing AS variants In fact, all AS mutants outcompeted wild-type HIV-1, as illustrated for the AS19 variant (Fig 6A) The results for all AS variants are summarized in Table ... own mRNA due to processing by the RNAi machinery We postulate that the lhNef hairpin may induce an antiviral response against wild-type HIV-1 either through a sequence-...
Ngày tải lên: 13/08/2014, 09:20
Inhibition of copper corrosion by orthophosphate a mechanistic study
... particular surface and the chemistry of the corrosion process A single surface will display distinct anodic and cathodic Tafel slopes ( a and βc) A large value of β means that a surface polarizes ... satisfactory inhibition effect on lead leaching from brass pipes It works as an “aging accelerator”, which means that the leaching of lead dramatically decreased and the duration...
Ngày tải lên: 22/10/2015, 22:43