Immunomodulatory roles of heat shock proteins

... in the absence of OVA (No), or in the presence of 50 µg/mL OVA (ova), 50 µg/mL of OVA plus 5-200 µg/mL of respective heat shock proteins (Hsp/ova), 50 µg/mL of OVA plus 100 µg/mL of lactorferrin ... absence of OVA (No), or in the presence of 50 µg/mL OVA (ova), 50 µg/mL of OVA plus 5-200 µg/mL of respective heat shock proteins and 20 µg/mL PMB(Hsp/ova) , 50 µg/...

Ngày tải lên: 09/10/2015, 11:06

... coronal section and scheme of the coronal section at E14.5 in (F) (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline Surprisingly, the ... binding is reduced, indicating that HSF4 facilitates HSF1 binding via chromatin remodelling Heat shock genes are not HSF4 targets, but HSF4 regulates a set of nonclassical h...

Ngày tải lên: 18/02/2014, 04:20

... 40 80 12 0 16 0 200 A 10 1 10 2 FL2-H 10 3 10 4 72Q 72Q+NAC Counts 40 80 12 0 16 0 200 10 0 10 1 10 2 FL2-H 10 3 10 4 B 10 3Q 10 3Q+NAC Counts 40 80 12 0 16 0 200 10 0 10 0 10 1 10 2 FL2-H 10 3 10 4 Fig Analysis of mitochondrial ... vector (72Q) or httEx1 -10 3Q-EGFP vector (10 3Q) Transfections were performed with a combination of those encoding Hsp70 ⁄ Hdj -...

Ngày tải lên: 19/02/2014, 06:20

... LOCAL INDUCTION OF HEAT SHOCK PROTEINS USING MAGNETIC FLUID HYPERTHERMIA FOR OCULAR- NEUROPROTECTION IN GLAUCOMA MINHONG JEUN A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... 7.4 141 Local Induction of HSPs 72 in RGCs by MFH 7.4.1 Optimization of concentration of EMZF@PEG SPNPs and holding time of AC heating stress for induction...

Ngày tải lên: 09/09/2015, 10:08

... structure of cytosolic class II small heat shock proteins Plant Physiol 114, 1477–1485 Basha, E & Vierling, E (2003) Cloning and sequencing of a new cytosolic class II small heat shock protein from wheat ... molecular chaperone activity of plant recombinant small heat shock proteins Methods Enzymol 290, 350–365 Helm, K.W., LaFayette, P.R., Nagao, R.T.,...

Ngày tải lên: 07/03/2014, 15:20

... oligomerization and Dynamics of bacterial sHsps (Eur J Biochem 271) 2501 Fig Hypothetical model on chaperone dynamics and chaperone substrate interaction of small heat shock proteins (sHsps) ... 45 and 38 kDa (B) Elution profile at 25 °C of a sample diluted from mgÆmL)1 (arrow) to 0.5 mgÆmL)1 elution of standard proteins was completely independent of temperature...

Ngày tải lên: 23/03/2014, 12:20

... mammalian a- crystallins, the oligomerization principles of bacterial a- Hsp proteins have received little attention Available data indicate that a- Hsp proteins from prokaryotes and plants may ... principles of a- Hsp assembly and the relation between complex formation and chaperone activity, we constructed a series of truncated and point-mutated a- Hsp varian...

Ngày tải lên: 31/03/2014, 21:21

... INVESTIGATIONS ON THE ROLES OF UBIQUITIN IN THE REGULATION OF HEAT SHOCK GENE HSP70B EE THIAM HEE, GARY NATIONAL UNIVERSITY OF SINGAPORE 2 011 INVESTIGATIONS ON THE ROLES OF UBIQUITIN IN THE ... THE REGULATION OF HEAT SHOCK GENE HSP70B EE THIAM HEE, GARY (B SCI (HONS), NUS A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY...

Ngày tải lên: 10/09/2015, 08:27

... regulation of transcription In this project we investigated the role of ubiquitin in the regulation of the heat shock gene HSP70B Through RNA interference of SKP1, a component of an ubiquitin ligase ... Role of Med21/hSrb7 in the Regulation of HSP70B 109 3.7 The Effect of the RNA Interference of Med21/hSrb7 and its Effects on Proteosomal...

Ngày tải lên: 10/09/2015, 08:27

... as the link between the methylation of histone H3 residues lysine 34 and lysine 79 (H3K34 and H3K79) and the ubiquitination of histone H2B, abrogating the methylation of H3 while leaving the ubiquitinated ... 2005) 1 .3. 4 E4 Ubiquitin Ligases in the Elongation of Polyubiquitin Chains While the E3 ubiquitin ligases mediate the initial ubiquitination of the s...

Ngày tải lên: 10/09/2015, 08:28

... among the regulation of nucleolin ⁄ C23, the activation of caspase-3 and the induction of apoptosis under the setting of oxidative stress and Hsp70 overexpression More importantly, for the first ... Xiao X (2009) ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived...

Ngày tải lên: 16/02/2014, 09:20

... into the nucleus upon heat shock and may activate nonclassical heat shock genes, but does not activate classical heat shock genes (i.e HSP genes) HSF1 prefers long arrays of the nGAAn unit, while ... region of HSP genes Unlike yeast HSP genes, the DNase I hypersensitive region of the hsp70 promoter of nonheat-shocked cells contains paused Pol II, which is transcriptional...

Ngày tải lên: 18/02/2014, 04:20

... Dementia, gliosis and expression of the small heat 2625 Small heat shock proteins and disease 120 121 122 123 124 125 126 127 128 shock proteins Hsp27 and [alpha]B-crystallin in Parkinson’s disease Neuroreport ... case in point, formation of huntingtin-containing inclusion bodies in Huntington’s disease encourages cell survival, whereas monomers and smal...

Ngày tải lên: 19/02/2014, 18:20

... Heat shock protection against cold stress of Drosophila melanogaster Mol Cell Biol 8, 35503552 Joplin KH, Yocum GD & Denlinger DL (1990) Cold shock elicits expression of heat shock proteins in ... processes involve expression of some Hsps in Drosophila [40,57] Finally, it has been suggested that expression of Hsps during recovery from cold might...

Ngày tải lên: 06/03/2014, 09:22