chaperones clp and htra proteases and heat shock proteins

... CJCGM (1999) Dementia, gliosis and expression of the small heat 2625 Small heat shock proteins and disease 120 121 122 123 124 125 126 127 128 shock proteins Hsp27 and [alpha]B-crystallin in Parkinson’s ... a-crystallin-related small heat shock proteins: HspB1–10 Cell Stress Chaperones 8, 53–61 2622 Y Sun and T H MacRae 23 Taylor RP & Benjamin IV (2005) Small heat shock proteins: a new classification ... other molecular chaperones, with disruption of HSPs that protect deregulated intracellular signaling proteins and transcription factors 2619 Small heat shock proteins and disease Y Sun and T H MacRae...

Ngày tải lên: 19/02/2014, 18:20

... D Mittal et al Heat shock element types and heat shock factors in rice Introduction The synthesis of heat shock proteins (Hsps) represents one of the most thoroughly ... substrate and by filter lift assay (Yeast Protocols Handbook; Clontech Laboratories Inc., Mountain View, CA, USA) Each experiment was repeated three times Heat shock element types and heat shock factors ... AP (2007) Transcriptional profiling of Arabidopsis heat shock proteins and transcription factors reveals extensive overlap between heat and non -heat stress response pathways BMC Genomics 8, 125...

Ngày tải lên: 05/03/2014, 23:20

... Genealogy of the a-crystallin-small heat- shock protein superfamily Int J Biol Macromol 22, 151–162 Sun, W., Van Montagu, M & Verbruggen, N (2002) Small heat shock proteins and stress tolerance in plants ... mediated most efficiently by ClpB/DnaK J Biol Chem 278, 31033–31042 10 MacRae, T.H (2000) Structure and function of small heat shock/ a-crystallin proteins: established concepts and emerging ideas Cell ... Chaperone activity and homoand hetero-oligomer formation of bacterial small heat shock proteins J Biol Chem 275, 37212–37218 Lentze, N., Studer, S & Narberhaus, F (2003) Structural and functional...

Ngày tải lên: 23/03/2014, 12:20

... time of heat shock, plated and CFU counted The proportions of viable cells expressing the pET 16b-MTB HSP 16.3 vector and the two control vectors were plotted for 0, and h following heat shock ... with and without MTB HSP 16.3 and aB-crystallin shifted to 48 °C The proportion of viable cells that survived heat shock at 48 °C was plotted at three time points (t ¼ 0, and h after 48 °C heat shock) ... (2000) Small heat- shock proteins and their potential role in human disease Curr Opin Struct Biol 10, 52–59 Landry, J., Chretien, P., Lambert, H., Hickey, E & Weber, L.A (1989) Heat shock resistance...

Ngày tải lên: 23/03/2014, 21:21

... the role of the serine ⁄ threonine kinase akt and the 90 kDa heat shock protein Mol Pharmacol 65, 407– 415 Song Y, Zweier JL & Xia Y (2001) Heat- shock protein augments neuronal nitric oxide synthase ... FEBS 2503 In vivo degradation of NOS and HSP90 by calpain M Averna et al Table Levels of native and 15 kDa calpastatin species in brain and aorta of NMS and HMS rats treated with HSD for weeks ... SDS-PAGE and blotted as described previously nNOS, eNOS and HSP90 were detected with specific mAbs (C) nNOS (open circles) and HSP90 (filled circles) immunoreactive materials detected in (A) and the...

Ngày tải lên: 30/03/2014, 04:20

... structure and function of the small heat shock proteins in plants J Exp Bot 47, 325–338 Arrigo, A.-P & Landry, J (1994) Expression and Function of the Low-molecular-weight Heat Shock Proteins ... (2002) Evolution and diversity of prokaryotic small heat shock proteins Prog Mol Subcell Biol 28, 1–17 41 Narberhaus, F (2002) a-Crystallin-type heat shock proteins: Socializing minichaperones in ... HspD, HspE and HspH) and two class B proteins (HspC and HspF), as well as the class A E coli proteins IbpA and IbpB A representative example Ó FEBS 2002 from each class, A (HspH) and B (HspF),...

Ngày tải lên: 31/03/2014, 21:21

... infection or heat shock Stress conditions like heat shock, infections, radiation, and exposure to chemicals induce increased levels of heat shock proteins in many cell lines [9] The heat shock proteins ... 24 h or heat shock treated (44°C, 20 min) or heat shock treated and recovered for or h at 37°C (shift assay) Lane – control cells, lane – heat shock treated, lane – heat shock treated and recovered ... RT-PCR1analysis of the heat shock factor blood macrophages RT-PCR analysis of the heat shock factor and heat shock proteins in vaccinia virus infected human blood macrophages HSF1, HSP70, HSP90α and β-actin...

Ngày tải lên: 11/08/2014, 08:21

... mitochondrial depolarization [33,34] and impaired clearance of oxidized proteins [35] Heat shock or stress proteins (Hsps) are expressed in neurons of polyQ diseased brains and have recently been identified ... polyglutamine-expanded proteins Hum Mol Genet 12, 2301–2309 31 Ding Q & Keller JN (2001) Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins J Neurochem ... Swartz J, Furlong RA, Narain Y, Rankin J & Rubinsztein DC (2000) Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington’s...

Ngày tải lên: 19/02/2014, 06:20

... The expanding family of small Hsps and other proteins containing an a-crystallin domain Cell Stress Chaperones 6, 225–237 Waters, E.R & Vierling, E (1999) Chloroplast small heat shock proteins: ... class II small heat shock proteins Plant Physiol 114, 1477–1485 Basha, E & Vierling, E (2003) Cloning and sequencing of a new cytosolic class II small heat shock protein from wheat Egypt J Biotechn ... a-crystallin-small heat- shock protein superfamily Int J Biol Macromol 22, 151–162 Studer, S & Narberhaus, F (2000) Chaperone activity and homoand hetero-oligomer formation of bacterial small heat shock proteins...

Ngày tải lên: 07/03/2014, 15:20

... presence in tumor tissues and decreasing proangiogenic TGF-β, TNF-α, MMP-9 and VEGF Subsequently, tumor angiogenesis, tumor growth and metastases were suppressed [39] Heat- shock proteins First discovered ... TNF-α Figure Heat- shock protein signal cascade Heat- shock protein signal cascade Necrotic tumorderived mammalian gp96 and HSP70 can signal antigen-presenting cells (APCs) via CD14, and other receptors ... review attempts to assemble the evidence implicating heat- shock proteins in the neoplastic process Ever since the crucial role of heat shock proteins in cancer pathophysiology was established,...

Ngày tải lên: 10/08/2014, 22:20

... 123 7.2 Magnetic Properties and AC Heating Characteristics 126 7.2.1 Magnetic and AC heating properties of solid state EMZF SPNPs 126 7.2.2 Coating status and AC heating characteristics of coated ... Néel and Brown relaxation loss power to the AC heating power of fluidic SPNPs e Understand the physical mechanisms of the AC heating and the crucial physical parameters to improve the AC heating ... Uptake 3.5 59 59 Identification of Induction of Heat Shock Proteins 72 - Cell Staining (Fluorescein Isothiocyanate and 4’, 6-Diamino-2Phenylindole) and Western Blot Analysis 60 3.6 61 Infusion of...

Ngày tải lên: 09/09/2015, 10:08

... since the heat shock response was first reported in a Drosophila study [Ritossa, 1962] The heat shock proteins (HSPs) are highly conserved proteins that are expressed constitutively and inducibly ... Gething and Sambrook, 1992] and degradation of proteins [Parsell and Lindquist, 1993], to resolubilise proteins aggregates [Ning and Sanchez, 1995], to assist in the refolding of denatured proteins ... recombinant heat shock proteins under native condition M bovis Hsp65, B pseudomallei Hsp70 and Hsp60 were expressed and purified from E coli cells that were transformed to express the respective heat shock...

Ngày tải lên: 09/10/2015, 11:06

... vertebrate heat shock factor system: Hsf3 and Hsf4 Cell Stress Chaperones 4, 86–93 Pirkkala L, Nykanen P & Sistonen L (2001) Roles of the heat shock transcription factors in regulation of the heat shock ... Calderwood SK (2005) Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo Cell Stress Chaperones 10, 46–58 ` Rossi ... NY Wu C (1995) Heat shock transcription factors: structure and regulation Annu Rev Cell Biol 11, 441–469 Fernandes M, O’Breien T & Lis JT (1994) Structure and regulation of heat shock gene promoters...

Ngày tải lên: 18/02/2014, 04:20

... [41] Mouse HSF3 translocates into the nucleus upon heat shock and may activate nonclassical heat shock genes, but does not activate classical heat shock genes (i.e HSP genes) HSF1 prefers long arrays ... achieved by HSF1 and the histone deacetylases HDAC1 and HDAC2 [77] In heatshocked cells, HSF1 binds to HDAC1 and HDAC2, and their histone-deacetylase activities increase The heat- induced deacetylation ... acetylase and deacetylase modulate chromatin structure and fine-tune transcription [58] The histone chaperones Asf1, Spt6 and Spt16 are involved in histone eviction and redeposition, and inactivation...

Ngày tải lên: 18/02/2014, 04:20

... FEBS R Abane and V Mezger 113 Trinklein ND, Chen WC, Kingston RE & Myers RM (2004) Transcriptional regulation and binding of heat shock factor and heat shock factor to 32 human heat shock genes ... tm1Anak) provided a mechanism for HSF1dependent heat shock- induced cell death in spermatocytes [86] Heat shock does not trigger the induction of major heat shock genes in male germ cells The prominent ... Christians E, Michel E & Renard JP (1997) Developmental control of heat shock and chaperone gene expression Hsp 70 genes and heat shock factors during preimplantation phase of mouse development...

Ngày tải lên: 18/02/2014, 04:20

... Biology of Heat Shock Proteins and Molecular Chaperones Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York Wu, C (1995) Heat shock transcription factors: structure and regulation ... observed gel shift bands in the lanes containing epitopetagged HSF1 (Fig 6B, lanes and 8) The bands were detected at a position corresponding to the gel-shift band of heat- shocked RTG-2 cell extract ... cycles of 0.5 at 94 °C, 0.5 at 50 °C and 0.5 at 72 °C, and one termination cycle of at 72 °C, with 35 cycles in total for HSF1a and HSF1b and 30 for heat shock cognate 70 (HSC70) Rainbow trout...

Ngày tải lên: 19/02/2014, 12:20

... evolutionary and ecological role of heat shock proteins Ecol Lett 6, 10251037 Parsell DA & Lindquist S (1993) The function of heat- shock proteins in stress tolerance: degradation and reactivation ... Trends Ecol Evol 18, 257262 Feder ME & Hofmann GE (1999) Heat- shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology Annu Rev Physiol 6, 243282 Hoffmann ... Denlinger DL (1990) Cold shock elicits expression of heat shock proteins in the esh y, Sarcophaga crassipalpis J Insect Physiol 36, 825834 Petersen NS, Young P & Burton V (1990) Heat- shock m-RNA accumulation...

Ngày tải lên: 06/03/2014, 09:22

... Structure and properties of the small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins Biochemistry (Mosc) 67, 511–519 Macario AJL (1995) Heat- shock proteins and molecular chaperones: ... Small heat- shock proteins and their potential role in human disease Curr Opin Struct Biol 10, 52–59 Renkawek K, Stege GJJ & Bosman GJCGM (1999) Dementia, gliosis and expression of the small heat shock ... small heat shock proteins hsp27 and aB-crystallin in Parkinson’s disease NeuroReport 10, 2273–2276 10 Head MW & Goldman JE (2000) Small heat shock proteins, the cytoskeleton, and inclusion body...

Ngày tải lên: 07/03/2014, 04:20

... Small heat shock proteins and stress tolerance in plants Biochim Biophys Acta 1577, 1–9 Horwitz J (2003) Alpha-crystallin Exp Eye Res 76, 145–153 Laksanalamai P & Robb FT (2004) Small heat shock proteins ... concepts and emerging ideas Cell Mol Life Sci 57, 899–913 Scharf K-D, Siddique M & Vierling E (2001) The expanding family of Arabidopsis thaliana small heat stress proteins and a new family of proteins ... containing a-crystallin domains (Acd proteins) Cell Stress Chaperones 6, 225–237 Narberhaus F (2002) a-crystallin-type heat shock proteins: socializing minichaperones in the context of a multichaperone...

Ngày tải lên: 07/03/2014, 12:20

... [12,13] As a major stress-inducible heat shock protein, heat shock protein (HSP) 70 has been shown to protect cells from a number of apoptotic stimuli, including heat shock, tumor necrosis factor, ... expression at a level similar to that of the endogenous proteins induced by heat shock This system mimics the antiapoptotic effects of heat shock and is very instrumen2618 tal with respect to our investigation ... activation of caspases-9 and -3 and apoptosis (A) The effects of HSP70 and its deletion mutant proteins on the activation of caspases-9 and -3 were analyzed Cells over-expressing HSP70 and its deletion...

Ngày tải lên: 16/03/2014, 01:20