Expression and roles of microRNAs in cell cycle

... Differential expression of miRNAs during cell cycle phases 67 5.2 Role of miR-210 in cell cycle 69 5.3 Role of miR-193a in cell cycle 73 5.4 Roles of miR-122a, miR-96 and miR-107 in cell cycle 78 ... Over -expression of let-7 in cancer cell lines alters cell cycle progression and reduces cell division, and it has been shown that multiple ge...

Ngày tải lên: 05/10/2015, 22:31

... Differential expression of miRNAs during cell cycle phases 67 5.2 Role of miR-210 in cell cycle 69 5.3 Role of miR-193a in cell cycle 73 5.4 Roles of miR-122a, miR-96 and miR-107 in cell cycle 78 ... Over -expression of let-7 in cancer cell lines alters cell cycle progression and reduces cell division, and it has been shown that multiple ge...

Ngày tải lên: 06/10/2015, 20:35

... meaning and relevance to the cell cycle It is of interest to look at the basic data in Table of Liu, Gaido and Wolfinger [1] In Table they present results on the gene expression amplitudes in two ... experiment Summary The work of Liu, Gaido and Wolfinger [1] is a statistical analysis of a well-regarded paper [2] on the pattern of g...

Ngày tải lên: 13/08/2014, 23:20

... Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells Suha Saleh1,2, Fiona Wightman1,2, Saumya Ramanayake1, Marina Alexander3, Nitasha Kumar1,2, ... primary Tcells Others have demonstrated the synergism obtained by treatment with a combination of prostratin and the HDACi vorinostat in both a...

Ngày tải lên: 13/08/2014, 01:21

... only around 50% If the number of time points in exp2 One often neglected but important factor in interpreting and analyzing cell cycle related gene expression data is the quality of synchrony of ... cycle related genes In a single cell, the amplitude and phase of a cell cycle related gene are considered two independent parameters in a sinusoidal model Within a...

Ngày tải lên: 13/08/2014, 23:20

... Global analysis of microRNA target gene expression reveals the potential roles of microRNAs in maintaining tissue identity Zhenbao Yu* , Zhaofeng Jian, Shi-Hsiang Shen, Enrico Purisima, and Edwin ... its targets for their expression Theoretically, the tissues with low level of the expression of the targets of a miRNA are probably the tissues in...

Ngày tải lên: 14/08/2014, 16:20

... Consequently, the molecular studies of the interaction of SAgs with their specifics ligands will not only advance understanding of the physiological mechanisms of these molecules, but may lead to the development ... Fig 1B–D, expression of the mutant yields only monomeric SSA, free of dimer T-cell proliferation assay We next analyzed the ability of recombinan...

Ngày tải lên: 07/03/2014, 16:20

... Hemolymph titers of PO -CHH and ES -CHH in response to changes in dissolved oxygen Hypoxia induced the release of CHHs from the PO and ES of the juvenile crabs (Fig 6) At the initial control normoxic ... of CHH cDNA from the ES [28] Also, we examined the physiological responses of the release and expression of these two CHHs under stressful co...

Ngày tải lên: 16/03/2014, 06:20

... analysis of chemokine receptor gene expression in synovial fluid polymorphonuclear neutrophils (a) RNA of synovial fluid polymorphonuneutrophils clear neutrophils (SF PMN) from nine patients with ... Research & Therapy Vol No Auer et al Figure Induction of CCL18 mRNA and protein in synovial fluid and blood polymorphonuclear neutrophils (a) Synovial flu...

Ngày tải lên: 09/08/2014, 10:21

... Trk-A and Trk-B by human disc cells in terms of disease pathology has yet to be fully examined A role for the proinflammatory cytokines TNFα and IL-1β in innervation of the IVD [22] and in degeneration ... Trk-A and Trk-B protein expression in the nondegenerate and degenerate human IVD Immunopositive staining for Trk-A and Trk-B was largely cellular in...

Ngày tải lên: 09/08/2014, 11:20

... their 2′-Omethylation to remain stable in the presence of highly complementary targets [102] Reciprocally, instability of Page of 13 Drosophila miRNAs loaded in AGO1 was induced by providing them ... origins and arrangements reflect distinct evolutionary styles of canonical miRNAs in plants and animals Non-canonical biogenesis pathways for inverted repeat transcripts: mi...

Ngày tải lên: 09/08/2014, 22:24

... on the role of the retinoblastoma gene family in cell cycle regulation and tumor suppression The pRb Cell Cycle Control Pathway: Components and the Cancer Connection The retinoblastoma protein, ... over-expression of D-type cyclins, mutations rendering Cdk4 The Retinoblastoma Gene Family 185 Fig The p16INK4A -pRb and the p19ARF -p53 pathwa...

Ngày tải lên: 25/10/2013, 21:20

... be involved in recognition of the methylated Lys4 amino group Multidomain organization of LSD1 and its enzymatic activity in the chromatin context Genes coding for LSD1 ⁄ K -demethylase proteins ... protein–protein and DNA–protein interactions [36] The name of this domain derives from its original identification in the proteins SWI3, Rsc8 and Moira, which are ATP-depen...

Ngày tải lên: 16/03/2014, 02:20

... Immunohistochemical staining of PKCε in tissue specimens PKCε is overexpressed in both cytoplasm and nuclei of clear cell renal cell carcinoma (RCC) cells (A) Primary antibody isotype control (B) and ... radical nephrectomy or partial resection Of the 128 RCC samples, 10 were papillary RCC, 10 were chromophobe RCC, and 108 were clear cell RCC according to the 2002...

Ngày tải lên: 10/08/2014, 10:21

... Regulation of G1/ S transition and induction of apoptosis in HL-60 leukemia cells by fenretinide (4HPR) Int J Cancer 1998, 78:53-61 Darzynkiewicz Z, Bedner E, Smolewski P: Flow cytometry in analysis of ... distribution and the expression of various cell cycle regulatory proteins in HL-60 cells Figure Effects of LA on cell cycle phase distributio...

Ngày tải lên: 10/08/2014, 22:20