Distinct histone deacetylases repress expression of LH and FSH beta genes in the immature gonadotrope alphat3 1 cells and the repression is reversed by GNRH

... DISTINCT HISTONE DEACETYLASES REPRESS EXPRESSION OF LH AND FSH β GENES IN THE IMMATURE GONADOTROPE αT3 -1 CELLS AND THE REPRESSION IS REVERSED BY GNRH YANG MENG A THESIS SUBMITTED FOR THE ... Gonadotropin-releasing hormone (GnRH) regulates LH and FSH βsubunit synthesis 10 1. 2 .1 Basal expression of LH and FSH β-subunit genes...

Ngày tải lên: 04/10/2015, 16:03

... 13 and had the insertion of the transposon in this plasmid as indicated by the plasmid profile and hybridization experiments Previous studies Expression of afimbrial adhesion genes in avian septicemic ... transformant strains and the reference plasmids Lane 1: Strain V517 (32 MDa), Lane 2: Strain SEPT13, Lane 3: Strain ST16, Lane 4: Recipient strain MS101 harboring the 9...

Ngày tải lên: 07/08/2014, 20:23

... Gene expressions of mature miR9 and miR9* during neuronal differentiation (A) Using real-time PCR The gene expressions of endogenous mature miR9 and miR9* during the neuronal differentiation of P19 ... for expression of pri-miR9-1 expression of pri-miR9-1 expression of pri-miR9-2 expression of pri-miR9-2 expression of pri-miR9-3 expression of...

Ngày tải lên: 18/02/2014, 17:20

... suppression of respiration during hypoxia In the absence of differential regulation of a speci c nuclear gene coding for the subunits of CytOX, changes in the microenvironment of the cell may induce alterations ... modulates the expression of mRNAs for CytOX subunits and also the catalytic activity of the enzyme complex Our results show tha...

Ngày tải lên: 20/02/2014, 23:20

... Variations in the residues involved in the binding at site of the human FABP1, and possibly in zebrafish FABP1a and zebrafish FABP1b, may reflect differences in the binding affinities of the zebrafish ... during embryogenesis and therefore may not perform a function equivalent to mammalian FABP1 during zebrafish embryogenesis The distinct patterns of ex...

Ngày tải lên: 07/03/2014, 12:20

... FEBS N Pinchai et al Cell type expression of spherulin 3b and polymalatase Fig Structural alignment of amino acid sequence by motifs, of spherulin 3b with spherulin 3a and other members of the bc-crystallin ... ([6] and references therein), suggesting the presence of detectable amounts of PMLA synthetase -specific mRNA The absence of PMLA and polymal...

Ngày tải lên: 07/03/2014, 12:20

... autoradiographs of the amplified products and the quantification of the bands is shown in the bottom panels Rb and Sp1 mRNA levels were determined from the ratio of the intensities between the Rb or Sp1 and the ... inhibitors We report that the expression of retinoblastoma and Sp1 is increased by low concentrations of CDK inhibitors...

Ngày tải lên: 16/03/2014, 23:20

... [7], although kinetic studies [8] indicate that its alanineglyoxylate aminotransferase activity is not favored over aminobutyrate-pyruvate, b-alanine-pyruvate and dimethylarginine-pyruvate aminotransferase ... (p97) cofactor (p47) Aminoacylase Phosphoglycerate mutase Indolethylamine N-methyltransferase Peroxiredoxin Apolipoprotein A- I Abhydrolase domain containing 14b D-Amino Protein na...

Ngày tải lên: 23/03/2014, 03:20

... (between and 24 h) used by the authors In another study, 258 differentially expressed genes were identified in C gigas in response to exposure to hydrocarbons for and 21 days [22], and some of these genes ... among the down -regulated genes Expression of herbicide -regulated genes The time-dependent expression of 13 genes that were up -regul...

Ngày tải lên: 30/03/2014, 15:20

... that the F-11 cells not only express the rat VRL-1, but also the mouse VRL-1 and that the mouse variant is derived from the F-11 parental cell line N18TG2 This finding is of interest when VRL-1 ... A, B and D of F-11 cells again separated into two bands The slower migrating band always corresponded to the rat brain control, and the faster migr...

Ngày tải lên: 31/03/2014, 07:20

... Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells Journal of Translational ... DNR-insensitive CD34+ AML cell lines (KG1a and Kasumi-1) and in CD34+ primary AML samples We showed that curcumin selective...

Ngày tải lên: 18/06/2014, 19:20

... (0.3 11 ) (1. 0–5.0) 14 (1. 0–40) CCR7 24 (8.0–40) (3.0–6.5) 17 (13 – 21) 13 (9.0 17 ) 19 (17 –20) (2.0 11 ) CXCR3 10 (5.0 18 ) 15 (8.0–23) (2.8–6.5) (1. 0–4.0) 10 4 (54 16 0) 36 (14 –59) CXCR4 11 (4.8 14 ) (1. 7–4.0) ... Cornea and Trigeminal Ganglia (TG) Corneaa TGb Gene 3d 10 d 30d 3d 10 d 30d CCR1 11 (9.2 12 ) 18 (13 –23) 20 (10 –26) (2.2–7 .1) 15 (9.0 19 ) (1. 7–7.0) CCR2...

Ngày tải lên: 18/06/2014, 22:20

... SM-ceramide cascade-signaling in expression of iNOS and cytokines [12] These observed alterations of SM-Cer- and ROS-mediated signaling, with LPS /Aβ- induced expression of proinflammatory mediators, by antioxidant ... treatment [19] These above studies demonstrate AICAR attenuation of LPS- or cytokine /Aβ- induced expression of inflammatory mediators (e.g iNOS, C...

Ngày tải lên: 19/06/2014, 22:20

... an alternative activation gene profile Alternative activation gene profiles in mouse models of AD Since alternative activation could be demonstrated in vitro using the expression of specific genes, ... control individuals Additionally, we investigated the alternative activation- related gene expression profiles in mouse models of AD and of c...

Ngày tải lên: 19/06/2014, 22:20