in the inducible expression of antioxidant and detoxifying enzymes
Báo cáo khoa học: Myocyte enhancer factor 2B is involved in the inducible expression of NOX1⁄ NADPH oxidase, a vascular superoxide-producing enzyme ppt
... indirectly regulate the expression of the NOX1 mRNA We therefore elucidated the role of ATF-1 in the MEF2B-dependent activation of NOX1 expression As shown in Fig 6, the expression of MEF2B mRNA induced ... cells by inducing the expression of the NOX1 gene Results Determination of the 5¢-end of the NOX1 mRNA expressed in VSMC We reported the expression of novel NOX1 transcripts (c- and f-types) in ... induction of NOX1 expression [8–10] Except for the involvement of ATF-1, the entire picture of the transcriptional regulation of the NOX1 gene has not been clarified yet In the upstream region of the...
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Báo cáo khoa hoc:" Despite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210" pptx
... organization of GP210 and a model of the deduced amino acid chain of GP210 Genomic organization of GP210 and a model of the deduced amino acid chain of GP210 Exons (black boxes) and intron sizes ... intron, and kb of the upstream promoter region of mouse GP210 Similar to human, a GPC island containing 644 bp and with a GC content of 74% was found starting 268 nt upstream of the start codon and ... other isoforms of WT1 regulate GP210 Figure WT1 isoform A does not regulate expression of GP210 WT1 isoform A does not regulate expression of GP210 SAOS cells conditionally expressing WT1 isoform...
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Tài liệu Báo cáo khoa học: Bioimaging of the unbalanced expression of microRNA9 and microRNA9* during the neuronal differentiation of P19 cells doc
... for for for for for for for expression of pri-miR9-1 expression of pri-miR9-1 expression of pri-miR9-2 expression of pri-miR9-2 expression of pri-miR9-3 expression of pri-miR9-3 neuronal differentiation ... cloned the upstream region of miR9 and studied the expression pattern of endogenous pri-miR9-1 to try to understand miR9 biogenesis during the neuronal differentiation of P19 cells using RT-PCR and ... positions and sequences used to amplify pri-miR9-1, 9-2 and 9-3 Arrows indicate the position and orientation of the primers Bold font represents the sequence of mature miR9* and italic fonts the sequence...
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Trends in the European Investment Fund Industry in the Second Quarter of 2011 and Results for the First Half of 2011 potx
... Equity Balanced Total Equity & Balanced Funds of funds (4) Other Total (excl Ireland & Netherlands) of w hich guaranteed funds Total (incl Ireland & Netherlands) 36,733 in No in % (3) in No (1 No full ... regarding the strength of the global economic recovery and increasing tensions in the euro area, which sparked lower demand for equity and bond funds Differences in totals between quarterly and monthly ... billion during the first half of 2011, slightly behind the EUR 55 billion recorded in the first half of 2010 Long-term UCITS attracted EUR 87 billion during the first half of the year, down from...
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Trends in the European Investment Fund Industry in the Second Quarter of 2012 and Results for the First Half of 2012 pdf
... Funds of funds (4) Other Total (excl Ireland & Netherlands) of w hich guaranteed funds Total (incl Ireland & Netherlands) 35,766 (1 No full data breakdo wn is available fo r Ireland and the Netherlands; ... during the quarter (4.1%), and net assets of balanced funds reduced by 2.1 percent Funds of funds registered an increase in net assets of 1.7 percent during the quarter Over the first half of 2012, ... Quarter of 2012) Trends in the European Investment Fund Industry Net Assets by Country of Domiciliation The combined assets of the investment fund market in Europe, i.e the market for UCITS and nonUCITS,...
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Bloodletting Instruments in the National Museum of History and Technology pot
... at the end of the handle The advantages claimed by the inventor were ease in handling, ease in cleaning, and the diagonal cut of the blades that allowed the blood to flow more freely and the ... lever on the outside of the case The blade was positioned at right angles to the spring and case, thus adopting the basic shape of the fleam The case of the spring lancet was usually made of copper, ... the first exposing the blades, and the second rotating them a full 180 degrees Pressure on the release lever pushed the catch off the tooth on the cocking lever, thereby releasing the lever and...
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Common ground in the transcriptional profiles of wounds and tumors pps
... non-beneficial therapy Understanding repair and identifying targets Interestingly, comparison of the fibroblast signature with the expression profiles of various carcinomas (epithelialderived ... Distinct pattern of expression of differentiation and growth-related genes in squamous cell carcinomas of the head and neck revealed by the use of laser capture microdissection and cDNA arrays ... correlating with metastasis, and suggested that the bulk of cells within the tumor share this signature, and thus the metastatic potential is encoded within the bulk of the primary tumor [13] This...
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Báo cáo khoa hoc:" Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma progression" potx
... (mean = 54 and median = 55) The genotyping success rate was in the range from 98.2 to 99.5% and the retesting of the 10% randomly selected samples was 100% concordant MMP2 -1306 C/T and -735 C/T ... modify the production of proteolytic enzymes, and in turn modify the risk for melanoma progression Therefore, in this study, we sought to determine whether an association between MMP2 and MMP3 ... manuscript; PR and SS participated in the genotyping; AP coordinated the patients' accrual and updated the clinicopathological and epidemiological database; NI performed the statistical analysis and contributed...
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Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps
... demonstration of an inverse relationship between NF-κB and p53 nuclear localization and associated protein expression in tumors [35] As a result, and to further examine the validity of the results of the ... p53 status, which is consistent with either the loss of the negative regulation (PTEN and PPAR), or the suppression of NF-κB and other signal pathways and genes by gaining or retaining p53 functions ... alterations and the biological and clinical significance of NF-κB activation and of multiple NF-κB-regulated genes and cytokines expressed in HNSCC tumor specimens and serum [18,32,33,42,80,81], and the...
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THE ROLE OF TRANSFORMATIONAL LEADERSHIP BEHAVIORS IN AFFECTIVE EMPLOYEE ENGAGEMENT AN EMPIRICAL STUDY IN THE TWO INDUSTRIES OF RETAIL AND FINANCIAL SERVICES IN HO CHI MINH CITY
... the process of completing this thesis Without the support and encouragement from Dr Lam and Dr Tho, the thesis might not be possible in meeting the requirements and expectations of the research ... circumstances In the same meaning, the leadership effectiveness is combined both the qualities of the leaders and the demands of the situations In order to make a good decision, the leaders have ... as the leading factor, then other kinds of commitment The results of the study reflected the mean scores were consistent with the abovementioned by showing that the affective commitment had the...
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Sailfish habitat utilization and vertical movements in the southern gulf of mexico and florida straits
... beginning of dive, overall duration of dive, and the “interdive interval” (the period between the end of one dive event and the start of the next) Most dive events demonstrated a period of rapid ... utilization above and below respective SST and MLDT values for each 24-h period of the deployment The structure of the transmitted data from the PSATs allows for a re-creation of the thermal environment ... northward through the summer The movement of the majority of the tagged animals in this study northward along the Gulf of Mexico and Atlantic edges of the shelf supports the patterns observed by...
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A STUDY IN THE SELECTIVE POLYMORPHISM OF a AND b GLYCINE IN PURE AND MIXED SOLVENT
... [33] and [34] respectively 24 1.3 Structure of the Thesis The rest of the thesis is organized as follows First a literature review (Chapter 2) of the approaches used to study crystal growth and the ... interval of 50 ps, na b is the number of events over an interval of 50 ps and a is the average molecules of type a iv The system is then propagated in a Kinetic Monte Carlo simulation on the basis of ... energy, kB is the Boltzmann constant, T is the absolute temperature, and W is the multiplicity of the microscopic state The multiplicity of the microscopic state, W, is the number of possible combinations...
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Báo cáo y học: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury" ppt
... change their pI values and affect their mobility in the IPGs Although the phosphorylated/oxidized form of Prx1/6 and the nitrated form of MnSOD in 2DE remain to be identified, the intensities of the ... (Figure 2A) Given the fact that the reduction of the antioxidant enzymes in the LC at day and day 14 post SCI compared to that in sham-operated tissues (Figure 2A), we examined whether the neural cell ... reduce the possibility of the leakage of the injected fluid from the site The procedure of animal care was described as above Behavioral Analysis As previously described [24], animals received either...
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Tài liệu Freedom of Expression on the Internet - A study of legal provisions and practices related to freedom of expression, the free flow of information and media pluralism on the Internet in OSCE participating States ppt
... contradictory to the conclusions of the Final Document of the Moscow Meeting of the Conference on the Human Dimension of the CSCE and in breach of Article 19 of the International Covenant on Civil and Political ... or the economic well-being of the country, for the prevention of disorder or crime, for the protection of health of morals, or for the protection of the rights and freedoms of others Finally, the ... of the media across the OSCE region Second, the study assesses the impact these regulations and practices have on the free flow of information and the freedom of expression on the Internet The...
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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx
... switch and alters the expression of the two nuclear genome coded isoforms of CytOX V [10,32] The regulation of genes CytOX5a and CytOX5b, coding for the two isofoms Va and Vb, parallels that of genes ... shows the effects of hypoxia on the steady state levels of nuclear genome encoded CytOX IV and Vb mRNAs There was no change in the levels of these mRNAs in macrophages at h of hypoxia, the time ... measured the steady state CytOX mRNA levels The Northern blot in Fig shows the effect of hypoxia on the levels of mitochondrial genome- and nuclear genome-coded mRNAs for CytOX subunits There were...
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Báo cáo khoa học: Stage specific expression of poly(malic acid)-affiliated genes in the life cycle of Physarum polycephalum Spherulin 3b and polymalatase potx
... ([6] and references therein), suggesting the presence of detectable amounts of PMLA synthetase-specific mRNA The absence of PMLA and polymalatase in other cell types could be the result of cell ... substitutions, eight of them located in the first two b-strands of the N-terminal half of NKA48, upstream of the homodimer interface and accessible for interactions with other macromolecules It ... settings of the Lightcycler Software Version 3.5.3 and conditions in the linear range of the PCR-reaction were ensured Cell type expression of spherulin 3b and polymalatase Quantitative analysis of...
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Báo cáo khoa học: Expression of the pyrG gene determines the pool sizes of CTP and dCTP in Lactococcus lactis doc
... may have acted on the level of pyrG expression has been removed The strength of the feedback regulation of CTP on pyrG expression, i.e the elasticity of pyrG expression for the CTP concentration ... pyrG expression One of these strains has 43% pyrG expression relative to the wild-type and no growth defect at 30 C However, the two strains with the lowest pyrG expression levels at 34% of the ... [24] This theory predicts that for biosynthetic pathways, such as those leading to the biosynthesis of amino acids or nucleotides, the control of the ux should reside in the demand for the end-product,...
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Báo cáo khóa học: Cloning and expression of murine enzymes involved in the salvage pathway of GDP-L-fucose ppt
... restores the synthesis of GDP-fucose through the salvage pathway The salvage metabolism accounts for approximately only 10% of the intracellular pool of GDP-L-fucose [40] However, the enzymes of the ... only the de novo pathway alone, but also the salvage pathway could have an essential role in the synthesis of GDP-L-fucose in the cytosol The importance and the regulatory mechanisms of the enzymes ... levels of L-fucokinase and pyrophosphorylase The primer and probe sequences and their positions in the mRNA sequence, for GDP-L-fucose pyrophosphorylase and the short and long splice variants of...
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Báo cáo khoa học: Dual expression of mouse and rat VRL-1 in the dorsal root ganglion derived cell line F-11 and biochemical analysis of VRL-1 after heterologous expression pptx
... two bands The slower migrating band always corresponded to the rat brain control, and the faster migrating band to the N18TG2 control (Fig 5) The existence of both rat and mouse VRL-1 in the same ... only result in one band The slower migrating of the two F-11 PCR bands always corresponded to the rat brain control, the faster migrating band to the N18TG2 control In case of C the PCR product from ... vector (Invitrogen) and sequenced The accuracy of sequences from the open reading frame was checked by DNA sequencing of both strands The resulting sequences of specific bands were identical to...
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báo cáo hóa học: " 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia" pptx
... shows the expression of iNOS, MnSOD and COX-2 in glial cells Aβ peptide upregulated the LPSmediated expression of MnSOD Aβ peptides (1–40) and (1–42) induced the expression of iNOS, COX-2, and ... 172 of the α1/α2 subunits and on Ser 108 of the β subunit of AMPK AICAR treatment of glial cells activated AMPK as evident from the enhanced intensities of the phosphospecific protein bands of ... COX-2 expression and hence to the release of eicosanoids [55,60] ROS are yet another by-product of the conversion of arachidonic acid to prostanoids (prostaglandins and leukotrienes), and perhaps...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25