Clinical significance of cancer stem cell markers and other related proteins in colorectal carcinomas biological and methodological considerations
... both biological and methodological aspects of our hypothesis in determining clinical significance of cancer stem- cell marks in colorectal cancer Our main objective is to understand the clinical ... predictive effect of cancer stem cell markers in colorectal cancers (ii) examine the associations of cancer stem cell markers with KRAS and B...
Ngày tải lên: 03/10/2015, 20:57
... cases of invasive cancer than in cases of non-invasive cancer [8,9] The principal objective of this study was to determine the relationship between serum IL-6 and CRP levels and staging and prognosis ... significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients World Journal of Surgical Oncology 2011 9...
Ngày tải lên: 09/08/2014, 01:24
... cancer stem cell hypotheses, cancer stem cells are ideal seeds of metastasis Stem cells are indeed ideal carrier of gene mutations and their accumulation First, the initiating cell must be a cell ... Winslet M, Seifalian A: Stem cells and cancer: an overview Stem Cell Rev 2007, 3(4):249-55 Huntly B, Gilliland D: Leukaemia stem cells and the evolution of cancerstem...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Cancer stem cell subsets and their relationships" pot
... normal stem cells to primary cancer stem cells Precancerous lesions progress to cancer when precancerous stem cells transform into primary cancer stem cells [64] Second, precancerous stem cell ... Relationships among cancer stem cell subsets Up to now, precancerous stem cells, primary cancer stem cells and migrating cancer stem cells have been proven to e...
Ngày tải lên: 20/06/2014, 03:20
Báo cáo y học: ":Identification of novel stem cell markers using gap analysis of gene expression data" ppsx
... ebf4 ebf1 ebf2 cyp1a1 cyp1a2 cyp1b1 ) Figure Phylogenetic distribution of stem cell markers and their close paralogs in four protein families Phylogenetic distribution of stem cell markers and their ... undergone repeated gene duplication events for a phylogenetic analysis of the evolution of proteins involved in stem cell function By sequence similarity analysis,...
Ngày tải lên: 14/08/2014, 08:20
báo cáo khoa học: " LgR5 expression and cancer stem cell hypothesis: clue to define the true origin of esophageal adenocarcinomas with and without Barrett’s Esophagus?" ppsx
... that there is a subsequent clonal selection of putative stem cells [8] The expression profile of LgR5 in EAC without BE was comparable with the result of EAC with BE According to a longstanding cancer ... resemble the stem cell niche (arrows) Original magnification, × 200 (a) and × 400 (b) Page of 11 without BE, the results of LgR5 expression were...
Ngày tải lên: 10/08/2014, 10:21
university of california press fundamentals of the stem cell debate the scientific religious ethical and political issues dec 2007
... visit www.ucpress.edu University of California Press Berkeley and Los Angeles, California University of California Press, Ltd London, England © 2008 by The Regents of the University of California ... produces all of the cells of the immune system, including B cells for the circulation and the lymph nodes and spleen; T cells for the thymus; and...
Ngày tải lên: 11/06/2014, 12:52
báo cáo hóa học:" MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells" ppt
... cancer cells [8] and stabilizes the HER2 oncoprotein in pancreatic cancer cells [7] In the present study, we analyzed the expression of the HER2 protein in MUC4transfected ovarian cancer cells The ... exogenous MUC4 expression in ovarian cancer cells showed an increase in HER2 expression and colocalization, suggesting that MUC4 is involved...
Ngày tải lên: 20/06/2014, 07:20
báo cáo khoa học: "Expression and prognostic significance of cancer-testis antigens (CTA) in intrahepatic cholagiocarcinoma" ppt
... extent of immunostaining in sections and further graded into four groups: + : < 5% of tumor cells stained; ++ : 5-25% of tumor cells stained; +++ : > 25-50% of tumor cells stained; ++++ : > 50% of ... Journal of Experimental & Clinical Cancer Research 2011, 30:2 http://www.jeccr.com/content/30/1/2 Page of Figure Venn diagram depicting the overlap in the expression of ca...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: " Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases" pptx
... Marcos et al.: Expression, regulation and clinical significance of soluble and membrane CD14 receptors in pediatric inflammatory lung diseases Respiratory Research 2010 11:32 Submit your next manuscript ... inflammation/infection and may represent a promising marker and therapeutic target in respiratory diseases The expression, regulation and clinica...
Ngày tải lên: 12/08/2014, 11:21
Báo cáo y học: "Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults" pot
... designed and carried out the study planning and critically revised the manuscript GJ designed and carried out the study planning, participated in analysis and interpretation of the data, and critically ... The study included a baseline examination and followup examinations at approximately 2.7 and years The research conducted in this manuscript is in...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: "Liposarcoma cells with aldefluor and CD133 activity have a cancer stem cell potential" pot
... et al.: Liposarcoma cells with aldefluor and CD133 activity have a cancer stem cell potential Clinical Sarcoma Research 2011 1:8 Submit your next manuscript to BioMed Central and take full advantage ... percentage of cells displaying Aldefluor activity increased (data not shown) These findings indicate that the cells comprise a degree of plasticity, and tha...
Ngày tải lên: 13/08/2014, 15:21
Báo cáo y học: "Population genetics of cancer cell clones: possible implications of cancer stem cells" pptx
... SJ: Applying the principles of stem -cell biology to cancer Nat Rev Cancer 2003, 3:895-902 17 Campbell LL, Polyak K: Breast tumor heterogeneity: cancer stem cells or clonal evolution? Cell Cycle ... only in a subset of the cancer cells (the stem cells) we can see that for any size of tumour, because of the much smaller number of stem cells, clonal evolution is pre...
Ngày tải lên: 13/08/2014, 16:20
Roles of long non coding RNAs in human embryonic stem cell pluripotency and neural differentiation 1
... specification of midbrain dopamine neurons Radial glia cells are neuronal progenitors in vivo 10 11 14 1. 3 Long non- coding RNAs in biology 15 1. 3 .1 1.3.2 1. 3.2 .1 1.3.2.2 1. 3.2.3 Long non- coding RNAs in pluripotency ... pluripotency, and repressing differentiation simultaneously 18 1. 3.2 Long non- coding RNAs in neural developmen...
Ngày tải lên: 09/09/2015, 17:54
Roles of long non coding RNAs in human embryonic stem cell pluripotency and neural differentiation 2
Ngày tải lên: 09/09/2015, 17:54