Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH

... value in the group of myocytes subjected to ischemia/ reperfusion injury 30    3.2 NaHS induced cardioprotection via regulation of intracellular pH 3.2.1 Effect of NaHS on pHi in the rat ventricular ... the cell viability of cardiac myocytes subjected to ischemia (30 min) /reperfusion (10 min) C, group data show the protective effects of NaHS against the cardiac my...

Ngày tải lên: 02/10/2015, 17:13

... as: Chen et al.: Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction Journal of Translational ... adipose-derived mesenchymal stem cells (ADMSCs) After culturing for 14 days, majority of isolated adipose-derived stem cells expressing CD29 and CD90 character...

Ngày tải lên: 18/06/2014, 19:20

... glycogen in myocardium This promotes binding of Hexokinase II to the mitochondrial membrane and inhibition of mitochondria permeability transition pore (MPTP) opening Cyclic AMP- induced activation of ... analogue 8Br-cAMP-AM which activates both PKA and Epac effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotectiv...

Ngày tải lên: 30/08/2015, 13:58

... extract of Desmodium gangeticum root induces myocardial protection against ischemia reperfusion injury in isolated rat hearts, as indicated by the improved recovery of cardiac function, reduction in ... et al.: Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hea...

Ngày tải lên: 13/08/2014, 15:21

... the accumulation of metabolites and inorganic phosphate With a substantial decline in ATP, the Na+, K+-ATPase is inhibited, resulting in a further decline of K+ and an increase in Na+ Intracellular ... stress, and cell adherence They function in a three-tier module comprising of a MAPK kinase kinase, a MAPK kinase and a MAPK The mammalian MAPK can be subdivided into five f...

Ngày tải lên: 14/09/2015, 14:05

... transduction of copper, zinc-superoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury Journal of Translational Medicine 2011 ... (1:20) for followed by PI for 15 The apoptosis rate was evaluated by Flow cytometry Transduction of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardiu...

Ngày tải lên: 18/06/2014, 19:20

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Ngày tải lên: 07/08/2014, 18:21

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Ngày tải lên: 07/08/2014, 18:21

... Discussion Nerve pathology in acute ischemic injury has beeen delineated in peripheral nerve and reperfusion injury could amplify ischemic pathology Nerve ischemia plays a major role in the development ... blunt injury to the abdominal aorta J Trauma -Injury Inferction and Critical Care 2003, 55:795-799 Murry CE, Jennings RB, Reimer KA: Preconditioning with ischemia...

Ngày tải lên: 10/08/2014, 09:22

... competing interests Authors' contributions MN participating in drafting the manuscript RR participating in drafting the manuscript and statistical analysis GF participating in statistical analysis ... producing serious neurologic deficits and still technically feasible For this purpose, clamping of both the femoral artery and ipsilateral common iliac artery was perfo...

Ngày tải lên: 10/08/2014, 10:20

... particularly in combination with cisplatin administration [10] To the best of our knowledge, there have been no other studies investigating the direct or indirect protective effects of Amifostine in spinal ... achieve the highest concentration of its active metabolite during the time of free radical accumulation in spinal cord cells, by intra-aortic administr...

Ngày tải lên: 10/08/2014, 10:20

... Posttransplant strategies to reduce I/R injury include the administration of substances that interfere with the inflammatory process mainly with the action of chemokines, cytokines, or leukocyte infiltration ... play a crucial role in mediating I/R injury after transplantation An important group of pro-inflammatory cytokines is the interleukin-1 family Here particularly IL-1β is of in...

Ngày tải lên: 11/08/2014, 03:20

... Posttransplant strategies to reduce I/R injury include the administration of substances that interfere with the inflammatory process mainly with the action of chemokines, cytokines, or leukocyte infiltration ... play a crucial role in mediating I/R injury after transplantation An important group of pro-inflammatory cytokines is the interleukin-1 family Here particularly IL-1β is of in...

Ngày tải lên: 11/08/2014, 06:22