0

quality organ storage and ischemia reperfusion injury of kidney transplants

Báo cáo y học:

Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx

Báo cáo khoa học

... minutes of short ischemia with minute's intervals), and then hours of ischemia with hours of reperfusion Part 2: Long time effetcs of I/R and IP Group 1- I/R with long duration (7dR):4 hours of ischemia ... and days of reperfusion A total of 70 rats were used in the study The study was divided into two part Part included the biochemical examination of Ischemia, I/R and I/R+IP on sciatic nerves of ... nerve of rat is seen (sham group), Hematoxylen esozine 40× magnification days) of reperfusion, but also much more extended time (up to 42 days) of reperfusion [18] Between days and 14 days of reperfusion, ...
  • 5
  • 409
  • 0
Báo cáo sinh học:

Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt

Hóa học - Dầu khí

... of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardium and ischemia- reperfusion injury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusion injury in Page of ... both of PEP-1-SOD1 and PEP-1-CAT to rats with myocardial ischemia- reperfusion injury CK CK-MB and cTnT are widely present in the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and ... PEP-1-SOD1 and PEP-1-CAT cooperatively protected heart against ischemia- reperfusion injury by removing OFR Ischemia- reperfusion injury induces myocardial apoptosis [28,29] OFR produced during the reperfusion...
  • 11
  • 349
  • 0
Báo cáo sinh học:

Báo cáo sinh học: "Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction" ppt

Hóa học - Dầu khí

... ischemic injury and improving kidney function from acute damage through engraftment of MSCs in both glomerular and tubular structures, regeneration of tubular epithelium, augmentation of paracrine and ... apoptosis, and suppressing oxidative stress in this experimental setting of acute kidney IR injury The cause of discrepancy between mRNA and protein expressions of HO-1 on both day and day after ... expressions of NQO1, GR, and GPx, three anti-oxidative indicators, were remarkably lower in group than in groups and 3, and notably lower in Figure Histopathological scoring of ischemia- reperfusion...
  • 17
  • 327
  • 0
Báo cáo khoa học:

Báo cáo khoa học: " Influence of ascorbic acid on BUN, creatinine, resistive index in canine renal ischemia-reperfusion injury" pps

Báo cáo khoa học

... esaercni tpurba detartsnomed nim 09 rof aimehcsi gniwollof noisufreper laner ,yduts suoiverp a nI puorg lortnoc ni detartsnomed erew noisufreper retfa syad 41 dna erofeb yletaidemmi seulav erapmoc ... raluremolg eht ni esaerced eht rof sisab eht eb ot deredisnoc si hcihw elubut eht fo nemul otni sdehs dna sisotpopa /sisorcen seogrednu tnemges lamixorp eht ,eroferehT ]9[ aimehcsi cimrehtomron ... morf gnirevocer retfa retaw dna doof dewolla erew slamina ehT enidoi-enodivop %01 gniylppa yb dezilirets saw dnuow eht dna desolc saw ytivac lanimodba ehT demrofrep saw ymotcerhpen thgir eht neht...
  • 3
  • 273
  • 0
Báo cáo khoa học:

Báo cáo khoa học: "Attenuation of ischemia-reperfusion injury by ascorbic acid in the canine renal transplantation" pps

Báo cáo khoa học

... erofeb seitivitca TAC dna xPHSG puorg tnemtaert dna lortnoc eht neewteb secnacifingis lacitsitats ;50.0 < p* spuorg htob rof DS ± naem sa desserpxe era seulav ehT noisufreper fo h 27 yb dewollof ... puorg tnemtaert susrev lortnoc rof secnacifingis lacitsitats ;50.0 < p* spuorg htob rof DS ± naem eht sa desserpxe era seulav ehT noisufreper fo h 27 yb dewollof noitatnalpsnartotua laner retfa ... a rof nekat erew yendik tfel eht morf selpmas eussit ehT ld/gm 8.1< ot dezilamron dah seulav eninitaerc mures eht fi keew tnalpsnart-tsop driht eht retfa seninac gnivivrus eht gnizinahtue rof...
  • 5
  • 180
  • 0
Báo cáo y học:

Báo cáo y học: "Ipsilateral common iliac artery plus femoral artery clamping for inducing sciatic nerve ischemia/reperfusion injury in rats: a reliable and simple method" doc

Báo cáo khoa học

... reliability of a method for sciatic nerve ischemia- reperfusion injury Microsurg 2007, 27(3):206-207 Iida H, Schmelzer JD, Schmeichel AN, et al.: Peripheral nerve ischemia: reperfusion injury and fiber ... studies showing IFD and profound axonal edema at days Iida [4] also reported a third phase of fiber regeneration with only minimal edema and fiber debris at 28 and 42 days of reperfusion; but, ... JD, et al.: Effect of ischemia and reperfusion in vivo on energy metabolism of rat sciatic-tibial and caudal nerves Exp Neurol 1991, 114:315-320 Publish with Bio Med Central and every scientist...
  • 4
  • 264
  • 0
Báo cáo y học:

Báo cáo y học: "Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits" docx

Báo cáo khoa học

... mechanism of spinal cord injury after ischemia- reperfusion consists of progressive loss of motor neurons accompanied with a steady decline of motor function [3] The complexity of this mechanism is ... occlusion (phase 5) and at the onset of reperfusion (phase 6) Sedation was maintained by intravenous administration of Propofol 1% (PROPOFOLđ, Astra Zeneca, Chershire, UK), (0.6 mg/kg), and Fentanyl ... failure of aerobic energy metabolism and lactate accumulation, b) activation of mitochondrial and cytoplasmic nitric oxide synthase (NOS) and production of nitric oxide [25], c) activation of phospholipase...
  • 12
  • 349
  • 0
Báo cáo y học:

Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot

Báo cáo khoa học

... manifestation of the reperfusion injury Idstrom [12] utilised a period of 2, and h cold 25°C hind limb ischaemia in rats and one hour reperfusion to measure damage and recovery of adenine nucleotides ... contribute to ischaemia reperfusion injury of fast-, mixed fast/ slow- and slow-twitch muscle types Viability of these Page of (page number not for citation purposes) Journal of Inflammation 2004, ... because of the wide variety of IR models in use In particular, there is a great deal of variation in the period of ischaemia, the muscle temperature during ischaemia and the period of reperfusion...
  • 7
  • 400
  • 0
Báo cáo y học:

Báo cáo y học: "CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice" docx

Báo cáo khoa học

... Wild-type mouse after 90 minutes of ischemia and h of reperfusion, (D) P/I null mouse after 90 minutes of ischemia and h of reperfusion ischemia followed by and 15 h of reperfusion were significantly ... and E) Wild-type mice subjected to 90 minutes of ischemia followed by and 15 h of reperfusion respectively; (D and F) P/I null mouse subjected to 90 minutes of ischemia followed by and 15 h of ... euthanized after and 15 h of reperfusion and the Page of 10 (page number not for citation purposes) Journal of Inflammation 2007, 4:11 blood and liver tissue were collected and processed, as...
  • 10
  • 398
  • 0
Báo cáo y học:

Báo cáo y học: "Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts" pps

Báo cáo khoa học

... enzymes from the assault of ischemia reperfusion injury (Table 4) Conclusion The ethyl acetate extract of Desmodium gangeticum root protects the myocardium against ischemia- reperfusioninduced damage ... made up to ml by adding distilled water and kept in a water bath at 100°C for hour After cooling, ml of distilled water and ml of a mixture of n-butanol and pyridine (15:1 v/v) was added The mixture ... minutes and remixed The absorbance of the organic layer was measured at 532 nm The percentage inhibition of lipid peroxidation was determined by comparing results of the test compounds with those of...
  • 7
  • 346
  • 0
Báo cáo y học:

Báo cáo y học: "Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice" potx

Báo cáo khoa học

... point in each group were studied Ischemia- reperfusion of the LAD An open-chest model of I/R using ligation and reperfusion of the LAD was modified from Michael and colleagues [36] Mice were anesthetized ... following ischemia/ reperfusion and persists throughout our seven day observation period Figure ing I/R of the of left Western blot LAD ventricular OTR levels at baseline and day following I/R of the ... regulation of vasopressin receptor subtype in the heart as a result of I/R Expression of V1R, V2R, and OTR in the heart was assessed in four mice per group at baseline and at day following I/R of the...
  • 8
  • 185
  • 0
Role of cyclic AMP signalling mechanisms in heart protection against ischemia   reperfusion injury

Role of cyclic AMP signalling mechanisms in heart protection against ischemia reperfusion injury

Tổng hợp

... ROS PKC Acknowledgements Doctor Andrew James Doctor Mark Bond Professor Saadeh Suleiman Professor Andrew P Halestrap Labs of Professor Saadeh Suleiman and Professor Andrew Halestrap ... activates both PKA and Epac effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotective effect of cAMP Scheme of Signal Transduction of the cAMPInduced ... 2007;581:1147-61 Study of the signalling mechanisms of cardioprotective effect of temperature preconditioning have revealed that this intervention is mediated by consecutive activation of PKA and PKC as...
  • 22
  • 213
  • 0
Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH

Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH

Cao đẳng - Đại học

... myocytes injury induced by ischemia and reperfusion for 10, 30, and 60 D, treatment with NaHS (100 μM) and KR (KR-32568; μM) alone or a combination of both protected myocytes against ischemia/ reperfusion ... 762.92% ±148.21% of the value before ischemia, while LVeDP of control group at 15 of reperfusion remained at 1273.32% ± 232.00% of the value before ischemia Our data suggest that hearts of control ... 3.03% of preischemia value at the first 15 of reperfusion These data indicate that NaHS treatment significantly restored the contractility and compliance of hearts subjected to ischemia/ reperfusion...
  • 75
  • 152
  • 0
Báo cáo y học:

Báo cáo y học: " Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" ppt

Báo cáo khoa học

... remodeling after ischemia/ reperfusion injury Particularly the matrix metalloproteinases 2, 3, and have been shown to influence tissue repair In experimental models of I/R injury an inhibition of MMPs ... itself, the difficulty to assess organ viability during cold storage and the development of I/R injury all make passive cold storage difficult for future improvements of strategies Donor preconditioning ... mentioned problems of cold storage, I/R injury, cold injury and problems to assess graft viability during storage [74] Normothermic preservation has not only the potential to preserve organs but also...
  • 8
  • 252
  • 0
Báo cáo y học:

Báo cáo y học: " tài: Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" potx

Báo cáo khoa học

... remodeling after ischemia/ reperfusion injury Particularly the matrix metalloproteinases 2, 3, and have been shown to influence tissue repair In experimental models of I/R injury an inhibition of MMPs ... itself, the difficulty to assess organ viability during cold storage and the development of I/R injury all make passive cold storage difficult for future improvements of strategies Donor preconditioning ... mentioned problems of cold storage, I/R injury, cold injury and problems to assess graft viability during storage [74] Normothermic preservation has not only the potential to preserve organs but also...
  • 8
  • 421
  • 0
Báo cáo y học:

Báo cáo y học: " Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation" pdf

Báo cáo khoa học

... and drafted the manuscript JL and ILK helped with the analysis and interpretation of the data VEL helped in conception and design of the experiments, analysis and interpretation of the data and ... Jones ML, Deeb GM, Bolling SF, Ward PA: Pattern of injury and the role of neutrophils in reperfusion injury of rat lung J Surg Res 1995, 58:713-718 Bando K, Paradis IL, Similo S, Konishi H, Komatsu ... activation of A2AAR on resident lung cells would attenuate pulmonary injury and dysfunction after IR despite the absence of circulating platelets and leukocytes from blood reperfusion Methods Animals and...
  • 9
  • 128
  • 0
Báo cáo y học:

Báo cáo y học: "Cellular infiltrates and injury evaluation in a rat model of warm pulmonary ischemia–reperfusion" pot

Báo cáo khoa học

... late increase of neutrophils after hour of ischemia and hours of reperfusion • Significant apoptosis and lung oedema in the absence of necrosis after hour of ischemia and hours of reperfusion 12 ... after hour of warm ischemia followed by 30 to hours of reperfusion A first peak was shown after 30 of reperfusion and a second peak after hours of reperfusion Furthermore, after hours of reperfusion, ... blood/air barrier after only 30 of reperfusion Apoptotic cells appear after hours of reperfusion in a warm model of ischemia reperfusion and after 6–9 hours of reperfusion in a transplantation...
  • 8
  • 307
  • 0
Báo cáo sinh học:

Báo cáo sinh học: "Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model" potx

Điện - Điện tử

... consequences of lung ischemia- reperfusion injury and low-pressure ventilation J Surg Res 2009, 153:295-301 Bittner HB, Binner C, Dahlberg P, Mohr FW: Reducing ischemia- reperfusion injury in clinical ... Parenchyma after IschemiaReperfusion (IR) Injury Notably higher protein expressions of TNFa (A) and NF-B (B) in IR group than in normal control and IR + ADMSC groups, but lack of difference between ... percentages of all EPC surface markers were similar between day and day 14 of cell culture Additionally, the percentages of MSC surface markers of CD45+ and CD271+ cells did not differ between day and...
  • 13
  • 280
  • 0

Xem thêm