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ischemia reperfusion injury pathophysiology and treatment

Báo cáo sinh học:

Báo cáo sinh học: "Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction" ppt

Hóa học - Dầu khí

... groups and 3, and significantly lower in group than in group at 24 h and 72 h after IR injury On the other hand, this protein expression was markedly lower in group than in groups and 3, and notably ... elicited by IR injury and ADMSC treatment contributed to further anti-inflammatory and anti-oxidative effects after IR-induced renal injury in this study Findings from Immunofluorescent and IHC Staining ... expressions of NQO1, GR, and GPx, three anti-oxidative indicators, were remarkably lower in group than in groups and 3, and notably lower in Figure Histopathological scoring of ischemia- reperfusion (IR)-induced...
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Báo cáo sinh học:

Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt

Hóa học - Dầu khí

... Transduction of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardium and ischemia- reperfusion injury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusion injury in Page ... tranduced into myocardium and protected against myocardial ischemiareperfusion injury in rats [12,14] To examine the combined effect of PEP-1-SOD1 and PEP-1-CAT, we applied both of PEP-1-SOD1 and ... myocardial ischemia- reperfusion injury CK CK-MB and cTnT are widely present in the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and cTnT are reliable indicators of myocardium injury...
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Báo cáo y học:

Báo cáo y học: "Ipsilateral common iliac artery plus femoral artery clamping for inducing sciatic nerve ischemia/reperfusion injury in rats: a reliable and simple method" doc

Báo cáo khoa học

... method for sciatic nerve ischemia- reperfusion injury Microsurg 2007, 27(3):206-207 Iida H, Schmelzer JD, Schmeichel AN, et al.: Peripheral nerve ischemia: reperfusion injury and fiber degeneration ... of peripheral nerve of rats from ischaemia -reperfusion injury Brain 1999, 122(Pt 1):161-169 Saray A, Can B, Akbiyik F, et al.: Ischemia- Reperfusion injury of the peripheral nerve: an experimental ... randomly divided into six groups: one control group and five I/R groups at different time intervals of reperfusions (0 h, h, d, d, d) All animals were anesthetized with ketamine (50 mg/kg) and...
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Báo cáo y học:

Báo cáo y học: " Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" ppt

Báo cáo khoa học

... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... chemoattractant protein-1 prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...
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Báo cáo y học:

Báo cáo y học: " tài: Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation" potx

Báo cáo khoa học

... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... chemoattractant protein-1 prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...
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Báo cáo y học:

Báo cáo y học: "CXC-chemokine regulation and neutrophil trafficking in hepatic ischemia-reperfusion injury in P-selectin/ICAM-1 deficient mice" docx

Báo cáo khoa học

... liver injury following hepatic ischemia/ reperfusion in the rat Hepatology 1996, 23:506 Jaeschke H, Farhood A: Neutrophil and Kupffer cell-induced oxidant stress and ischemia- reperfusion injury ... subjected to 90 minutes of ischemia followed by and 15 h of reperfusion respectively; (D and F) P/I null mouse subjected to 90 minutes of ischemia followed by and 15 h of reperfusion, respectively ... null and wild-type mice were subjected to 90 minutes of warm liver ischemia followed by various periods of reperfusion Hepatic I/R caused significant hepatocellular injury at and 15 h of reperfusion...
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Báo cáo y học:

Báo cáo y học: "Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice" potx

Báo cáo khoa học

... 2.9%, and 65.47 ± 2.4% in arginine vasopressin (AVP; n = 14), normal saline solution (SL; n = 9), and dobutamine (DOB; n = 6), resepctively Following ischemia/ reperfusion (I/R) injury, AVP treatment ... to 56.0), and AVP treatment 54.73% (52.1 to 57.3) In mice subjected to I/R injury, AVP treatment significantly reduced day LVEF to 46.2% (34.4 to 52.0) in comparison with both baseline and with ... point in each group were studied Ischemia- reperfusion of the LAD An open-chest model of I/R using ligation and reperfusion of the LAD was modified from Michael and colleagues [36] Mice were anesthetized...
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Báo cáo hóa học:

Báo cáo hóa học: " Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments" doc

Hóa học - Dầu khí

... conceived and wrote the review WB, JDR, EDW, and VC participated in literature search and selected appropriate articles PMH and HDS participated in design, coordination, and writing All authors read and ... diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments Annals of Intensive Care 2011 1:32 Submit your manuscript to a journal and ... and SLED the same level of evidence [49], although there are only very few randomized studies comparing SLED and CRRT, whereas there are large numbers of randomized studies that compare IHD and...
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AORTIC STENOSIS – ETIOLOGY, PATHOPHYSIOLOGY AND TREATMENT potx

AORTIC STENOSIS – ETIOLOGY, PATHOPHYSIOLOGY AND TREATMENT potx

Sức khỏe giới tính

... causing increased wear and tear on the valve leaflets Over time, excessive wear and tear leads to calcification, Aortic Stenosis Etiology, Pathophysiology and Treatment scarring, and reduced mobility ... New Insights in Stenosis Progression and in Prevention Parolari Alessandro, Trezzi Matteo, Merati Elisa, Filippini Sara and Alamanni Francesco Etiology and Pathophysiology 23 Chapter Aortic Stenosis: ... AI, B and E as predisposing factors for development of calcification and valvular stenosis (28) Finally, a unique study by Garg et al 10 Aortic Stenosis Etiology, Pathophysiology and Treatment...
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AORTIC STENOSIS – ETIOLOGY, PATHOPHYSIOLOGY AND TREATMENT pot

AORTIC STENOSIS – ETIOLOGY, PATHOPHYSIOLOGY AND TREATMENT pot

Sức khỏe giới tính

... causing increased wear and tear on the valve leaflets Over time, excessive wear and tear leads to calcification, Aortic Stenosis Etiology, Pathophysiology and Treatment scarring, and reduced mobility ... New Insights in Stenosis Progression and in Prevention Parolari Alessandro, Trezzi Matteo, Merati Elisa, Filippini Sara and Alamanni Francesco Etiology and Pathophysiology 23 Chapter Aortic Stenosis: ... AI, B and E as predisposing factors for development of calcification and valvular stenosis (28) Finally, a unique study by Garg et al 10 Aortic Stenosis Etiology, Pathophysiology and Treatment...
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Báo cáo y học:

Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx

Báo cáo khoa học

... McMarron PD: Reperfusion nerve injury pathology due to reflow and prolonged ischemia J Peripher Nerv Syst 1997, 2(1):60-69 Carden DL, Granger DN: Pathophysiology of ischemia- reperfusion injury J ... short ischemia with minute's intervals), and then hours of ischemia with hours of reperfusion Part 2: Long time effetcs of I/R and IP Group 1- I/R with long duration (7dR):4 hours of ischemia and ... Journal of Brachial Plexus and Peripheral Nerve Injury 2006, 1:2 with reperfusion [6] An aggrevated reperfusion injury in Streptozocine induced diabetic rats could be...
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Báo cáo y học:

Báo cáo y học: "Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits" docx

Báo cáo khoa học

... (Ca-1) and at the end of the experiment (Ca-8) It's noticed a decrease in Ca levels of 5.5% and 8% in (I) and (II) groups and 25% in (III) (animals 13 to 18) with antimutagenic, anticlastogenic and ... Diazoxide, Prevents Ischemia- Reperfusion Injury in the Rabbit Cord Am J Pathol 2006, 168:1443-1451 Pacher P, Beckman SJ, Liaudet L: Nitric Oxide and Peroxynitrite in Health and Disease Physiol ... measured at excitation 535 and emission 550 nm against butanol-treated sample and reagent blanks (0.15 ml sample plus 0.15 ml 20% TCA containing 0.33 N HCl and 0.02% w/v BHA, and 0.15 ml homogenate-buffer...
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Báo cáo y học:

Báo cáo y học: " Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation" pdf

Báo cáo khoa học

... the development of lung ischemia- reperfusion injury J Thorac Cardiovasc Surg 2003, 126:200-207 Day YJ, Huang L, Ye H, Linden J, Okusa MD: Renal ischemia- reperfusion injury and adenosine 2A receptor-mediated ... and drafted the manuscript JL and ILK helped with the analysis and interpretation of the data VEL helped in conception and design of the experiments, analysis and interpretation of the data and ... dysfunction from pulmonary ischemia- reperfusion injury Ann Thorac Surg 2005, 79:1189-1195 Rivo J, Zeira E, Galun E, Einav S, Linden J, Matot I: Attenuation of reperfusion lung injury and apoptosis by A2A...
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children and adolescents with type 2 diabetes andor metabolic syndrome pathophysiology and treatment

children and adolescents with type 2 diabetes andor metabolic syndrome pathophysiology and treatment

Nội khoa

... Normal weight and BP • < Age 25 and usually non-ketotic at presentation • Family history of diabetes without obesity • Negative ICA, IAA and GAD antibodies • Responds to insulin and sulfonylureas ... Children and Adolescents Food Plan and Exercise Metformin Mixed Insulin Physiologic Insulin International Diabetes Center Type Master DecisionPath for Children and Adolescents Food Plan and Exercise ... dose and assess for gastrointestinal discomfort Used for treatment of Polycystic Ovary Syndrome International Diabetes Center Type Master DecisionPath for Children and Adolescents Food Plan and...
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Báo cáo y học:

Báo cáo y học: "Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts" pps

Báo cáo khoa học

... starting treatments and global ischemia During the 30-minute global ischemia, there was a reduction in rate pressure product to zero, which started to recover gradually by continued reperfusion Pretreatment ... gangeticum orally for 30 days and then sacrificing them for reperfusion- induced ischemic injury Lipid peroxidation in drug treated rat hearts were reduced as compared to ischemia reperfusion control hearts ... factors for myocardial ischemia reperfusion injury [6] Xanthine dehydrogenase, which normally utilizes NADH as an electron acceptor, is converted under the conditions of ischemia/ reperfusion into xanthine...
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Báo cáo y học:

Báo cáo y học: "Recently published papers: Acute kidney injury – diagnosis and treatment" pdf

Báo cáo khoa học

... the choice of anticoagulant employed, and in particular the use of regional anticoagulation in order to address the loss of treatment time, additional costs and not least the nursing time associated ... study by Oudemans-van Straaten and colleagues should make you sit up and take notice [5] This study on 200 patients receiving continuous venovenous hemofiltration randomised patients to systemic ... this study were safety and efficacy powered on adverse events necessitating discontinuation of therapy as well as transfusion requirements, circuit survival and metabolic and clinical outcomes...
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