ischemia reperfusion injury and its induced lung injury

... groups and 3, and significantly lower in group than in group at 24 h and 72 h after IR injury On the other hand, this protein expression was markedly lower in group than in groups and 3, and notably ... NQO1, GR, and GPx, three anti-oxidative indicators, were remarkably lower in group than in groups and 3, and notably lower in Figure Histopathological scoring of ischemia- reperfusion (IR) -induced ... elicited by IR injury and ADMSC treatment contributed to further anti-inflammatory and anti-oxidative effects after IR -induced renal injury in this study Findings from Immunofluorescent and IHC Staining...

Ngày tải lên: 18/06/2014, 19:20

... Transduction of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardium and ischemia- reperfusion injury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusion injury in Page ... tranduced into myocardium and protected against myocardial ischemiareperfusion injury in rats [12,14] To examine the combined effect of PEP-1-SOD1 and PEP-1-CAT, we applied both of PEP-1-SOD1 and ... myocardial ischemia- reperfusion injury CK CK-MB and cTnT are widely present in the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and cTnT are reliable indicators of myocardium injury...

Ngày tải lên: 18/06/2014, 19:20

... method for sciatic nerve ischemia- reperfusion injury Microsurg 2007, 27(3):206-207 Iida H, Schmelzer JD, Schmeichel AN, et al.: Peripheral nerve ischemia: reperfusion injury and fiber degeneration ... of peripheral nerve of rats from ischaemia -reperfusion injury Brain 1999, 122(Pt 1):161-169 Saray A, Can B, Akbiyik F, et al.: Ischemia- Reperfusion injury of the peripheral nerve: an experimental ... techniques and instruments and the latter, albeit easily performable, does not produce severe injury [3] The aim of this study was to develop a practical model producing serious neurologic deficits and...

Ngày tải lên: 10/08/2014, 10:20

... liver injury following hepatic ischemia/ reperfusion in the rat Hepatology 1996, 23:506 Jaeschke H, Farhood A: Neutrophil and Kupffer cell -induced oxidant stress and ischemia- reperfusion injury ... subjected to 90 minutes of ischemia followed by and 15 h of reperfusion respectively; (D and F) P/I null mouse subjected to 90 minutes of ischemia followed by and 15 h of reperfusion, respectively ... ischemia and h of reperfusion, (D) P/I null mouse after 90 minutes of ischemia and h of reperfusion ischemia followed by and 15 h of reperfusion were significantly elevated when compared to their respective...

Ngày tải lên: 11/08/2014, 08:21

... purinoreceptors, we administered PPADS, a Figure ATP -induced lung edema and its mitigation by P2 receptor antagonist ATP -induced lung edema and its mitigation by P2 receptor antagonist A Time course ... Involvement of ATP in mechanical lung injury Worsening or induction of acute lung injury by mechanical ventilation is known as "VILI, and also as "ventilatorassociated" lung injury VILI is characterized ... isolated rat lung model J Clin Invest 1997, 99(5):944-952 Haitsma JJ, Uhlig S, Goggel R, Verbrugge SJ, Lachmann U, Lachmann B: Ventilator -induced lung injury leads to loss of alveolar and systemic...

Ngày tải lên: 12/08/2014, 14:20

... ventilator -induced lung injury: an experimental study Critical care medicine 2003, 31(3):885-892 Nin N, Penuelas O, de Paula M, Lorente JA, Fernandez-Segoviano P, Esteban A: Ventilation -induced lung injury ... after delivery Lung Processing and BAL Analysis The lungs were weighed, and bronchoalveolar lavage (BAL) was recovered by saline lavage of the left lung[ 24] Tissues from the left lung were snap ... ventilated controls Injury scores of betamethasone and dexamethasone exposed lungs showed decreased injury compared to Injury group (Table 2) The betamethasone group, compared to Injury animals,...

Ngày tải lên: 12/08/2014, 14:20

... point in each group were studied Ischemia- reperfusion of the LAD An open-chest model of I/R using ligation and reperfusion of the LAD was modified from Michael and colleagues [36] Mice were anesthetized ... 63.48 ± 2.9%, and 65.47 ± 2.4% in arginine vasopressin (AVP; n = 14), normal saline solution (SL; n = 9), and dobutamine (DOB; n = 6), resepctively Following ischemia/ reperfusion (I/R) injury, AVP ... Ballantyne CM: Myocardial ischemia and reperfusion: a murine model Am J Physiol 1995, 269:H2147-2154 37 Landry DW, Levin HR, Gallant EM, Ashton RC Jr, Seo S, D'Alessandro D, Oz MC, Oliver JA:...

Ngày tải lên: 13/08/2014, 16:21

... noisufreper -aimehcsi laner retfa xedni evitsiser fo segnahC giF eniporta fo doirep tnemtaerterP ;erP spuorg htob eht neewteb )10.0 < p( ecnereffid tnacifingis yllacitsitatS* DS htiw naem eht sa desserpxe ... spuorg htob fo sgod llA stluseR tnacifingis yllacitsitats sa nekat erew 50.0 < p ta secnereffiD tset-t tnedutS dna AVONA yb detaulave saw sisylana lacitsitatS stnemirepxe fo hcae rof )DS( noitaived ... saw ataD gnilpmas doolb fo emit eht ta detcudnoc osla erew seiretra lanerartni fo )IR( xedni evitsiser fo tnemerusaem htiw )aeroK ,nosideM( yhpargonos relppoD roloC derusaem erew negortin aeru...

Ngày tải lên: 07/08/2014, 18:21

... snaem a sa desserpxe era seulav eht llA p t sisylana lacitsitatS noitanimaxe ygolotsih dednilb a gnisu denimreted erew syendik eht fo scitsiretcarahc lacigolohprom ehT noitanimaxe ypocsorcim lacitpo ... 673 syendik eht ,tsartnoc nI )B & A4 giF( noitsegnoc dna selubut eht fo noitareneger ,noitartlifni llec yrotammalfni htiw gnola selubut eht fo noitalid citsyc etaredom detartsnomed deretsinimda ... yregrus erofeb seitivitca TAC dna xPHSG puorg tnemtaert dna lortnoc eht neewteb secnacifingis lacitsitats ;50.0 < p* spuorg htob rof DS ± naem sa desserpxe era seulav ehT noisufreper fo h 27 yb...

Ngày tải lên: 07/08/2014, 18:21

... short ischemia with minute's intervals), and then hours of ischemia with hours of reperfusion Part 2: Long time effetcs of I/R and IP Group 1- I/R with long duration (7dR):4 hours of ischemia and ... McMarron PD: Reperfusion nerve injury pathology due to reflow and prolonged ischemia J Peripher Nerv Syst 1997, 2(1):60-69 Carden DL, Granger DN: Pathophysiology of ischemia- reperfusion injury J ... Journal of Brachial Plexus and Peripheral Nerve Injury 2006, 1:2 with reperfusion [6] An aggrevated reperfusion injury in Streptozocine induced diabetic rats could be seen with...

Ngày tải lên: 10/08/2014, 09:22

... effective in the reduction of ROS levels produced in spinal cord cells during ischemia- reperfusion injury This drug and its trihydrate form is a pro-drug that is dephosphorylated in tissues to a ... (Ca-1) and at the end of the experiment (Ca-8) It's noticed a decrease in Ca levels of 5.5% and 8% in (I) and (II) groups and 25% in (III) (animals 13 to 18) with antimutagenic, anticlastogenic and ... Oxidative stress and Amifostine Oxidative stress and Amifostine The diagram demonstrates the cell damage when oxidative stress occurred and the Amifostine protective and repair effects after its activation...

Ngày tải lên: 10/08/2014, 10:20

... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... chemoattractant protein-1 prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...

Ngày tải lên: 11/08/2014, 03:20

... Long-term effects of acute ischemia and reperfusion injury Kidney Int 2004, 66:523-527 Kosieradzki M, Rowinski W: Ischemia/ reperfusion injury in kidney transplantation: mechanisms and prevention Transplant ... chemoattractant protein-1 prevents renal ischemia- reperfusion injury J Am Soc Nephrol 2003, 14:1066-1071 Wanderer AA: Ischemic -reperfusion syndromes: biochemical and immunologic rationale for IL-1 ... interaction between ischemia- reperfusion and immune responses in the kidney J Mol Med 2009, 87:859-864 Diepenhorst GM, van Gulik TM, Hack CE: Complement-mediated ischemia- reperfusion injury: lessons...

Ngày tải lên: 11/08/2014, 06:22

... 10:58 Background Ischemia- reperfusion (IR) -induced lung injury remains the major cause of primary graft failure after lung transplantation [1,2] IR injury causes significant mortality and morbidity ... lung IR injury, and that specific activation of A2AAR, and not A1AR, A2BAR or A3AR, has broad anti-inflammatory effects that attenuate lung IR injury Although we anticipated that lung injury and ... of ischemia- reperfusion injury of rat lung Am J Pathol 1997, 150:1773-1784 Eppinger MJ, Jones ML, Deeb GM, Bolling SF, Ward PA: Pattern of injury and the role of neutrophils in reperfusion injury...

Ngày tải lên: 12/08/2014, 14:20

... gangeticum orally for 30 days and then sacrificing them for reperfusion- induced ischemic injury Lipid peroxidation in drug treated rat hearts were reduced as compared to ischemia reperfusion control hearts ... from the assault of ischemia reperfusion injury (Table 4) Conclusion The ethyl acetate extract of Desmodium gangeticum root protects the myocardium against ischemia- reperfusioninduced damage in ... factors for myocardial ischemia reperfusion injury [6] Xanthine dehydrogenase, which normally utilizes NADH as an electron acceptor, is converted under the conditions of ischemia/ reperfusion into xanthine...

Ngày tải lên: 13/08/2014, 15:21

... both PKA and Epac effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotective effect of cAMP Scheme of Signal Transduction of the cAMPInduced ... Coronary Artery Occlusion and Heart Attack Heart Attack Myocardium Atheroslcerosis Reperfusion Thrombosis Risk Zone IschaemiaReperfusion INJURY Experimental Protocol C IP TP SHP ... ROS PKC Acknowledgements Doctor Andrew James Doctor Mark Bond Professor Saadeh Suleiman Professor Andrew P Halestrap Labs of Professor Saadeh Suleiman and Professor Andrew Halestrap ...

Ngày tải lên: 30/08/2015, 13:58

... myocytes injury induced by ischemia and reperfusion for 10, 30, and 60 D, treatment with NaHS (100 μM) and KR (KR-32568; μM) alone or a combination of both protected myocytes against ischemia/ reperfusion ... protect hearts against ischemia/ reperfusion- induced injury (Karmazyn 2001), we further tested whether NaHS could also protect the cardiac myocytes against ischemia/ reperfusion injury The experimental ... preischemia value at the first 15 of reperfusion These data indicate that NaHS treatment significantly restored the contractility and compliance of hearts subjected to ischemia/ reperfusion injury...

Ngày tải lên: 02/10/2015, 17:13

... investigating biofilm and its induced biocorrosion of two SRB strains on stainless steel 316 (SS316), and (iv) biofilm and biocorrosion prevention using an organic inhibitor and a layer-by-layer ... Introduction 1.5 Objectives and Scope of This Work The aims of this thesis are to examine the role of microorganisms in biofilm formation and its induced corrosion of metals, and to investigate in ... zero deflection and constant compliance portions of the curves (Razatos et al., 1998) 2.5 Biofilm and Biocorrosion of Stainless Steel AISI 316 and Its Prevention 2.5.1 Biofilm and Biocorrosion...

Ngày tải lên: 12/09/2015, 09:08