... groups and 3, and significantly lower in group than in group at 24 h and 72 h after IR injury On the other hand, this protein expression was markedly lower in group than in groups and 3, and notably ... NQO1, GR, and GPx, three anti-oxidative indicators, were remarkably lower in group than in groups and 3, and notably lower in Figure Histopathological scoring of ischemia- reperfusion (IR) -induced ... elicited by IR injuryand ADMSC treatment contributed to further anti-inflammatory and anti-oxidative effects after IR -induced renal injury in this study Findings from Immunofluorescent and IHC Staining...
... Transduction of PEP-1-SOD1 and/ or PEP-1-CAT in rat myocardium and ischemia- reperfusioninjury To observe whether transduced PEP-1-SOD1 and PEP-1CAT protect myocardial ischemia- reperfusioninjury in Page ... tranduced into myocardium and protected against myocardial ischemiareperfusion injury in rats [12,14] To examine the combined effect of PEP-1-SOD1 and PEP-1-CAT, we applied both of PEP-1-SOD1 and ... myocardial ischemia- reperfusioninjury CK CK-MB and cTnT are widely present in the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and cTnT are reliable indicators of myocardium injury...
... method for sciatic nerve ischemia- reperfusioninjury Microsurg 2007, 27(3):206-207 Iida H, Schmelzer JD, Schmeichel AN, et al.: Peripheral nerve ischemia: reperfusioninjuryand fiber degeneration ... of peripheral nerve of rats from ischaemia -reperfusion injury Brain 1999, 122(Pt 1):161-169 Saray A, Can B, Akbiyik F, et al.: Ischemia- Reperfusioninjury of the peripheral nerve: an experimental ... techniques and instruments and the latter, albeit easily performable, does not produce severe injury [3] The aim of this study was to develop a practical model producing serious neurologic deficits and...
... liver injury following hepatic ischemia/ reperfusion in the rat Hepatology 1996, 23:506 Jaeschke H, Farhood A: Neutrophil and Kupffer cell -induced oxidant stress and ischemia- reperfusioninjury ... subjected to 90 minutes of ischemia followed by and 15 h of reperfusion respectively; (D and F) P/I null mouse subjected to 90 minutes of ischemia followed by and 15 h of reperfusion, respectively ... ischemiaand h of reperfusion, (D) P/I null mouse after 90 minutes of ischemiaand h of reperfusionischemia followed by and 15 h of reperfusion were significantly elevated when compared to their respective...
... purinoreceptors, we administered PPADS, a Figure ATP -induced lung edema andits mitigation by P2 receptor antagonist ATP -induced lung edema andits mitigation by P2 receptor antagonist A Time course ... Involvement of ATP in mechanical lunginjury Worsening or induction of acute lunginjury by mechanical ventilation is known as "VILI, and also as "ventilatorassociated" lunginjury VILI is characterized ... isolated rat lung model J Clin Invest 1997, 99(5):944-952 Haitsma JJ, Uhlig S, Goggel R, Verbrugge SJ, Lachmann U, Lachmann B: Ventilator -induced lunginjury leads to loss of alveolar and systemic...
... ventilator -induced lung injury: an experimental study Critical care medicine 2003, 31(3):885-892 Nin N, Penuelas O, de Paula M, Lorente JA, Fernandez-Segoviano P, Esteban A: Ventilation -induced lunginjury ... after delivery Lung Processing and BAL Analysis The lungs were weighed, and bronchoalveolar lavage (BAL) was recovered by saline lavage of the left lung[ 24] Tissues from the left lung were snap ... ventilated controls Injury scores of betamethasone and dexamethasone exposed lungs showed decreased injury compared to Injury group (Table 2) The betamethasone group, compared to Injury animals,...
... point in each group were studied Ischemia- reperfusion of the LAD An open-chest model of I/R using ligation andreperfusion of the LAD was modified from Michael and colleagues [36] Mice were anesthetized ... 63.48 ± 2.9%, and 65.47 ± 2.4% in arginine vasopressin (AVP; n = 14), normal saline solution (SL; n = 9), and dobutamine (DOB; n = 6), resepctively Following ischemia/ reperfusion (I/R) injury, AVP ... Ballantyne CM: Myocardial ischemiaand reperfusion: a murine model Am J Physiol 1995, 269:H2147-2154 37 Landry DW, Levin HR, Gallant EM, Ashton RC Jr, Seo S, D'Alessandro D, Oz MC, Oliver JA:...
... short ischemia with minute's intervals), and then hours of ischemia with hours of reperfusion Part 2: Long time effetcs of I/R and IP Group 1- I/R with long duration (7dR):4 hours of ischemiaand ... McMarron PD: Reperfusion nerve injury pathology due to reflow and prolonged ischemia J Peripher Nerv Syst 1997, 2(1):60-69 Carden DL, Granger DN: Pathophysiology of ischemia- reperfusioninjury J ... Journal of Brachial Plexus and Peripheral Nerve Injury 2006, 1:2 with reperfusion [6] An aggrevated reperfusioninjury in Streptozocine induced diabetic rats could be seen with...
... effective in the reduction of ROS levels produced in spinal cord cells during ischemia- reperfusioninjury This drug andits trihydrate form is a pro-drug that is dephosphorylated in tissues to a ... (Ca-1) and at the end of the experiment (Ca-8) It's noticed a decrease in Ca levels of 5.5% and 8% in (I) and (II) groups and 25% in (III) (animals 13 to 18) with antimutagenic, anticlastogenic and ... Oxidative stress and Amifostine Oxidative stress and Amifostine The diagram demonstrates the cell damage when oxidative stress occurred and the Amifostine protective and repair effects after its activation...
... 10:58 Background Ischemia- reperfusion (IR) -induced lunginjury remains the major cause of primary graft failure after lung transplantation [1,2] IR injury causes significant mortality and morbidity ... lung IR injury, and that specific activation of A2AAR, and not A1AR, A2BAR or A3AR, has broad anti-inflammatory effects that attenuate lung IR injury Although we anticipated that lunginjuryand ... of ischemia- reperfusioninjury of rat lung Am J Pathol 1997, 150:1773-1784 Eppinger MJ, Jones ML, Deeb GM, Bolling SF, Ward PA: Pattern of injuryand the role of neutrophils in reperfusion injury...
... gangeticum orally for 30 days and then sacrificing them for reperfusion- induced ischemic injury Lipid peroxidation in drug treated rat hearts were reduced as compared to ischemiareperfusion control hearts ... from the assault of ischemiareperfusioninjury (Table 4) Conclusion The ethyl acetate extract of Desmodium gangeticum root protects the myocardium against ischemia- reperfusioninduced damage in ... factors for myocardial ischemiareperfusioninjury [6] Xanthine dehydrogenase, which normally utilizes NADH as an electron acceptor, is converted under the conditions of ischemia/ reperfusion into xanthine...
... both PKA and Epac effectively protects heart against ishaemia /reperfusion injury PKA and Epac act synergicaly in the cardioprotective effect of cAMP Scheme of Signal Transduction of the cAMPInduced ... Coronary Artery Occlusion and Heart Attack Heart Attack Myocardium Atheroslcerosis Reperfusion Thrombosis Risk Zone IschaemiaReperfusion INJURY Experimental Protocol C IP TP SHP ... ROS PKC Acknowledgements Doctor Andrew James Doctor Mark Bond Professor Saadeh Suleiman Professor Andrew P Halestrap Labs of Professor Saadeh Suleiman and Professor Andrew Halestrap ...
... myocytes injuryinduced by ischemiaandreperfusion for 10, 30, and 60 D, treatment with NaHS (100 μM) and KR (KR-32568; μM) alone or a combination of both protected myocytes against ischemia/ reperfusion ... protect hearts against ischemia/ reperfusion- inducedinjury (Karmazyn 2001), we further tested whether NaHS could also protect the cardiac myocytes against ischemia/ reperfusioninjury The experimental ... preischemia value at the first 15 of reperfusion These data indicate that NaHS treatment significantly restored the contractility and compliance of hearts subjected to ischemia/ reperfusion injury...
... investigating biofilm anditsinduced biocorrosion of two SRB strains on stainless steel 316 (SS316), and (iv) biofilm and biocorrosion prevention using an organic inhibitor and a layer-by-layer ... Introduction 1.5 Objectives and Scope of This Work The aims of this thesis are to examine the role of microorganisms in biofilm formation anditsinduced corrosion of metals, and to investigate in ... zero deflection and constant compliance portions of the curves (Razatos et al., 1998) 2.5 Biofilm and Biocorrosion of Stainless Steel AISI 316 andIts Prevention 2.5.1 Biofilm and Biocorrosion...