A mouse model of rhinovirus induced asthma exacerbation
A mouse model of rhinovirus induced asthma exacerbation 4
... instrumental undertaking of the pathogenesis of asthma exacerbation Airway inflammatory cells infiltration, mucus hyper-secretion and AHR are three hallmark features of asthma (Busse and Rosenwasser, ... Chapter Discussion 71 5.1 Development of rhinovirus- induced asthma exacerbation mouse model Rhinovirus infection is widely regarded as the major factor causing...
A mouse model of rhinovirus induced asthma exacerbation 5
... functionally polarized macrophages J Immunol Baltim Md 1 950 1 85, 252 5– 253 5 Nair, P., Gaga, M., Zervas, E., Alagha, K., Hargreave, F.E., OʼByrne, P.M., et al (2012) Safety and efficacy of a CXCR2 antagonist ... point of 86 inflammation peak and exacerbation Our model induced a fast eosinophilia exacerbation at day after last challenge, which is prior to the day peak in...
A mouse model of rhinovirus induced asthma exacerbation 2
... Inc, Waltham, MA, USA) Both A2 60 /A2 80 (DNA/protein) and A2 60 /A2 30 (DNA/organic contaminants) ratios were recorded as an indicator of purity of RNA An acceptable level of purity for RNA extracts ... were also made to establish asthma exacerbation models via rhinovirus infection, the major cause of human asthma exacerbation However, more than 90% of rhinovirus sero...
A mouse model of rhinovirus induced asthma exacerbation
... of asthma 1.1.3 Pathophysiology of asthma 1.2 Asthma exacerbation 1.2.1 Epidemiology of asthma exacerbation 1.2.2 Factors inducing asthma exacerbation ... and aggravate triggers and effectors (Lommatzsch, 2012) 1.2 Asthma exacerbation 1.2.1 Epidemiology of asthma exacerbation The natural history of asthma consists of relatively stable peri...
Báo cáo y học: " Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma" potx
... et al.: Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma Respiratory Research 2010 11:138 Submit your next manuscript ... function and airway inflammation caused by a potent oxidant like Cl2 is relatively under-investigated Recently a combination of anti-oxidants (ascorbic acid,...
Effects of anti malaria drug artesunate in the treatment of rhinovirus induced asthma exacerbation
... targeting the NF-κB cascade may be promising in the treatment of asthma 1.1.5 Therapeutic strategies in the treatment of asthma exacerbation There are currently some drugs for the treatment of rhinovirus- induced ... with the residues in other site of the surface These conserved sites have been shown to be the binding sites of the receptors and t...
Báo cáo y học: " Modulation of lung inflammation by vessel dilator in a mouse model of allergic asthma" doc
... peptides including LANP, VD and KP in modulating lung inflammation In this report we show that overexpression of VD attenuates airway inflammation in a mouse model of allergic asthma The effects of ... determine airway resistance values and peak values obtained after each MeCh challenge were plotted [16] Modulation of lung inflammation by VD To test the eff...
Báo cáo y học: " GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma" ppt
... (s.e.m.) After log transformation, airway responsiveness to methacholine was statistically analyzed by a general linear model of repeated measurements (ANOVA) followed by a post hoc comparison ... characterized by AHR, induction of specific IgE and airway eosinophilia We show for the first time that AHR is dramatically increased by GITR triggering at the time of alle...
Báo cáo y học: "An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study" pps
... Wedzicha JA: Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease [see comments.] American Journal of Respiratory & Critical ... review and nasal lavage on the days post-inoculation and on day 11 Clinic spirometry was performed on study days 4, and 11 At a final visit weeks after inoculation convalescent na...
Báo cáo sinh học: "Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer" pdf
... Shomura H, Homma S, Maeda Y, Tokunaga N, Ikeda Y, Ishihara Y, Yamada A, Tanaka N, Itoh K, Harada M, Todo S: Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil ... cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer Journal of Translational Medicine 2011 9:140 Submit your next manuscri...
báo cáo hóa học: " Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy" ppt
... et al.: Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy Journal of Neuroinflammation ... deeper microglial cells reside within the outer plexiform layer Of note, in all these layers microglial cells are often found in close associa...
Báo cáo y học: "Gait analysis in a murine model of collagen-induced arthritis" ppsx
... design, analysis and interpretation of data, and manuscript preparation JV contributed to study design, acquisition of data, analysis and interpretation of data, manuscript preparation, and statistical ... arthritis Arthritis Rheum 2007, 56:1164-1174 Sakuma M, Hatsushika K, Koyama K, Katoh R, Ando T, Watanabe Y, Wako M, Kanzaki M, Takano S, Sugiyama H, Hamada Y, et al.: TGF-beta t...
Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance docx
... of adenomatous polyposis coli (APC), somatostatin, carbonic anhydrase and tenascin C in the cerebellum (Figure 1a) and those of lysyl oxidase, carbonic anhydrase 4, enolase 3β and creatine kinase ... sensitive to thyroid hormone and the primary mode of T3 action is a direct influence on cardiac gene expression [20] Increased heart rate (tachycardia) and myocardial contractility...
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