Global gene expression changes caused by neurotoxins
Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx
... a series of events beginning with the TNFa-mediated prevention of the effect of insulin on Foxa2 localization and leading to the abrogation of insulin inhibition of gluconeogenesis and glucose ... status in the presence and absence of insulin and ⁄ or TNFa Figure 2A, B shows the effects of TNFa pretreatment on insulin action on the lo...
Báo cáo Y học: Prediction of temporal gene expression Metabolic optimization by re-distribution of enzyme activities ppt
... protein to the enzyme catalysing the following reaction The last switch allocates a nite fraction of protein to all enzymes whereby the rst enzyme of the chain (which has already done most of its ễworkế ... accompanied by concerted changes in the mRNA levels for most enzymes of the central metabolism of yeast resulting in down-regulation of glycolysis and up-regulation of...
Báo cáo Y học: Induction of chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI ) gene expression is mediated by ETS factor binding sites doc
... promoter activity (Fig 1B) Within the distal region, a putative Ets- 1 response element (site C, Fig 2A) was identi®ed by computer search for transcription factor binding sites [25] Surrounding this element, ... is stimulated by Ets- 1 to a similar extent as the )4 90 /)2 59 fragment (Fig 2A) in a dose-dependent manner (Fig 2B) Interestingly, the best putative Ets- 1 bind...
Báo cáo y học: " Large scale comparison of global gene expression patterns in human and mous" pot
... of expression profiles of tissue-specific genes and housekeeping genes is the foundation for the similar landscapes of sample clustering between human and mouse in large- scale transcriptome comparison ... Cell lines All 15 10 Windows of genes sorted by expression variance Figure Percentage of shared mouse and human orthologs in windows of 600 genes sorted b...
báo cáo khoa học: " Global gene expression analysis of apple fruit development from the floral bud to ripe fruit" pot
... one tomato sequence had homology to an apple gene and in the case of the tubulin genes to three apple genes For the tubulin genes the patterns of expression mostly differed between apple and tomato ... 60 50 Figure Comparison of apple and tomato expression Comparison of apple and tomato expression Expression of tomato and apple genes identified as cha...
Báo cáo y học: " Global gene expression patterns in the post-pneumonectomy lung of adult mice" ppt
... that indicates the likelihood of the genes in a network being found together due to chance A score of indicates a in 100 chance that the focus genes of interest were linked in the network by chance ... Illustrations of the top gene networks at the day time point of the time-dependent microarray analysis Figure Illustrations of the top gene networks at th...
Báo cáo y học: "Early gene expression changes with rush immunotherapy" ppt
... Carlsson L: DNA microarrays to study gene expression in allergic airways Clin Exp Allergy 2002, 32:301-8 29 Zhang RX, Yu SQ, Jiang JZ, Liu GJ: Complementary DNA microarray analysis of chemokines and ... identified through the use of gene profiling, but little is known about gene expression changes that occur with IT [11] Liu et al conducted a study to evaluate gene expression...
Báo cáo y học: "Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer" ppt
... myosin regulatory light chain interacting protein (MYLIP), myosin, light polypeptide kinase (MYL), myosin regulatory light chain 2, smooth muscle isoform (MYL9), calponin (CNN2) and fibronectin ... pathways underlying these effects Gene expression signatures paralleling a response to heterotypic interaction in this ex vivo model were shared by clinically distinct subgroups of...
Báo cáo y học: "Common gene expression strategies revealed by genome-wide analysis in yeast" ppt
... verify the consistency of the groupings obtained with these analyses, we tried different clustering methods For clustering analysis we assayed several normalization procedures, including ranking ... gene expression is a useful strategy to investigate the regulatory strategies used by a cell We conclude from our study that the synthesis rates for both mRNA and protein are the main de...
Báo cáo y học: "Spore germination in Saccharomyces cerevisiae: global gene expression patterns and cell cycle landmarks" potx
... rRNA processingGluconeogenesis stress rRNA Gluconeogenesis processing Stress TCA sub -cycle cell- cycle (G1) cell cycle G2/M cell cycle; M/G1 TCA Cell cycle Cell cycle Cell cycle sub -cycle (G1) (G2/M) ... germination and the following (first) mitotic cell cycle Septins were proposed to maintain cell polarity during the mitotic cell cycle By specifying a...
Gene expression changes in the brainstem and prefrontal cortex in a mouse model of orofacial pain
... microarray-based approaches to examine gene expression and miRNA changes in the brainstem and prefrontal cortex in a mouse facial carrageenan injection model of orofacial pain At the brainstem level, increased ... Inflammatory pain Tissue injury initiates an inflammatory response that induces pain This type of pain is known as inflammatory pain...
Global gene expression analysis of cranial neural tubes in embryos of diabetic mice
... the expression of genes that respond to hypoxia in cranial neural tubes of mouse embryos ……………………………………… 96 3.2.1 Expression of hypoxia-inducible factor 1α (Hif-1α) in cranial neural tubes of embryos ... altered in cranial neural tubes of embryos from diabetic mice …….………… 110 Expression of genes that are involved in glucose metabolism and t...
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