Regulation of subcellular localization and functions of RGK proteins by 14 3 3 and calmodulin

... relocalization of RGK proteins by 14- 3- 3 3- 3A Regulation of localization of Kir/Gem by 14- 3- 3 3- 3B Regulation of localization of Rad by 14- 3- 3 3- 3C Regulation of localization of Rem1 by 14- 3- 3 ... Regulation of localization of Rem1 L271G and mutants by 14- 3- 3 3- 5E Regulation of localization of Rem2 L317G an...

Ngày tải lên: 14/09/2015, 18:28

... Niinuma A, Ohashi M, Fukushi M, Oie M, Akiyama T, Tanaka Y, Gejyo F, Fujii M: PDZ domain-binding motif of human T-cell leukemia virus type Tax oncoprotein augments the transforming activity in a rat ... Yoshida S, Oie M, Tanaka Y, Takahashi S, Xie L, Green PL, Fujii M: Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human...

Ngày tải lên: 12/08/2014, 04:21

... natural transformation of T thermophilus HB27 Furthermore, we present the first information on the subcellular localization of the PilMNOWQ and PilA4 competence proteins and on the effect of mutations ... in pilQ led to the absence of PilW and PilA4 in the inner membrane In addition, pilW mutation resulted in the absence of PilQ and PilA...

Ngày tải lên: 07/03/2014, 12:20

... IRF -3 responsive, including the gene encoding arginase II (ArgII) ArgII is the extrahepatic isoform of the arginase type enzymes, and ArgI is the hepatic-specific counterpart [16] The two isoforms ... ArgII expression was inhibited by MG- 132 [20], suggesting indirectly an involvement of NF-jB in ArgII regulation Our study is thus the first direct demonstration...

Ngày tải lên: 07/03/2014, 21:20

... shared by Sec14p and Sfh proteins assumes functional significance because some of the Sec14 homologues (namely Sfh2 and Sfh4), when overexpressed, complemented the sec14-related growth and secretory ... could substitute for Sec14p in its role as a regulator of phospholipid biosynthesis Under conditions where Sec14p is nonfunctional and the CDP-choline pathway for Pt...

Ngày tải lên: 30/03/2014, 15:20

... suggest that proteolytic processing is a general mechanism for the negative regulation of STAT protein function (Fig 4) Truncated forms of Stat3 , Stat5 a, Stat5 b and Stat6 , generated by the proteolytic ... cells Proteolytic regulation of Stat5 and Stat3 in mature human neutrophils Stat3 and Stat5 isoforms have been identified in differentiated human perip...

Ngày tải lên: 30/03/2014, 15:20

... recruitment to the FeLV-945 LTR might interfere with CBP availability and thereby alter the regulation of CBP- responsive genes Such alteration might then contribute to altered hematopoiesis and consequent ... regulated by CBP in a manner dependent on the presence of the 21-bp triplication (Figure 7) These results indicated that the interaction between c-My...

Ngày tải lên: 18/06/2014, 22:20

... recruitment to the FeLV-945 LTR might interfere with CBP availability and thereby alter the regulation of CBP- responsive genes Such alteration might then contribute to altered hematopoiesis and consequent ... regulated by CBP in a manner dependent on the presence of the 21-bp triplication (Figure 7) These results indicated that the interaction between c-My...

Ngày tải lên: 20/06/2014, 04:20

... is likely that the caMEKK1-induced increases in NF-κB and RAR activity are mediated by hyperactivation of p300 Effect of caMEKK1 and ectopic p300 on Sox9 activity (a) Chondroactivity cytes were ... effect of TNF-α on Sox9 activity Finally, the sensitivity of Sox9 to atRA was reduced by caMEKK1 expression Thus, the activity state of p300, the common co-factor a...

Ngày tải lên: 09/08/2014, 10:22

... multi-domain protein, consisting of N-terminal SAM domain, C-terminal START domain and the catalytic RhoGAP domain This allows for its interaction with diverse cellular proteins, including FAK, Tensins ... light chain phosphatase (MLCP) to inactivate it and hence ensuring phosphorylation of myosin by myosin light chain kinase (MLCK) This leads to actin-myosin cross-linking, trig...

Ngày tải lên: 10/09/2015, 09:29

... treatment of ischemic stroke, a pathophysiological condition in which NMDA receptors are implicated 1.7 Tissue- type Plasminogen Activator (tPA) 1.7.1 tPA and stroke Tissue- type plasminogen activator (tPA) ... Thrombin 1.6.3.4 Tissue- type plasminogen activator (tPA) 22 23 23 24 25 26 27 27 27 29 30 30 30 32 1.7 Tissue- type Plasminogen Activator (tP...

Ngày tải lên: 11/09/2015, 10:18

... Phase and G2/M Checkpoints: In the budding yeast, DNA damage surveillance mechanisms operate in G1, S and G2 phases These are the G1 DNA damage checkpoint, the S phase replication and DNA damage checkpoints, ... REGULATION OF SPINDLE BEHAVIOR BY DNA REPLICATION AND DAMAGE CHECKPOINTS IN BUDDING YEAST SAURABH RAJENDRA NIRANTAR (B.Tech.(Hons)...

Ngày tải lên: 14/09/2015, 14:03

... integrated iron moiety and that NO+ from SNP is responsible for its effect on ferritin synthesis Moreover, acute regulation of ferritin synthesis by NO+ is accomplished by a rapid mobilization of polysome-free ... Mechanism of ferritin iron uptake: activity of the H-chain and deletion mapping of the ferro-oxidase site A study of iron uptake and ferro-oxidase...

Ngày tải lên: 07/03/2014, 12:20

... of 20 International Finance Regulation of Interest Rate by the State Bank of Vietnam (SBV) FOREWORD We would like to present to you our study on the Regulation of Interest Rate by the State Bank ... many bankers at the conference have given voice to the regulation on Page of 20 International Finance Regulation of Interest Rate by...

Ngày tải lên: 15/03/2014, 01:20

... role of each telomerase subunit in enzyme activity, we used downregulation of telomerase by inducing differentiation of HL-60 cells, and up -regulation of telomerase by stimulating proliferation of ... inhibition of TEP1 function by high concentrations of antisense oligonucleotides, telomerase activity was dramatically diminished Alternatively, hTR and hTERT ma...

Ngày tải lên: 17/03/2014, 23:20