Understanding the adaptive immune responses against newly emerged viruses, SARS coronavirus and avian h5n1 influenza a virus 2
Understanding the adaptive immune responses against newly emerged viruses, SARS coronavirus and avian h5n1 influenza a virus 2
... Epitope mapping of mAb 59 2. 22 Furin cleavage assay 59 2. 23 Virus binding assay 60 2. 24 Post-attachment assay 60 2. 25 Protease susceptibility assay 61 2. 26 Passive immunization and virus challenge ... coronavirus (SARS- CoV) and the H5N1 influenza A virus Together with innate immunity, the host adaptive immune responses are crucial for the clearance of the virus during an infection In the first ... VI vaccines against SARS as well as understanding memory T cell responses against novel acute infections In the second part of the study, a neutralizing monoclonal antibody (mAb) 9F4 against the...
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Understanding the adaptive immune responses against newly emerged viruses, SARS coronavirus and avian h5n1 influenza a virus 1
... Sunil K Lal, and Yee Joo Tan (2008) Comparing the antibody responses against recombinant hemagglutinin proteins of avian influenza A (H5N1) virus expressed in insect cells and bacteria Journal of ... Disease Control and Mikael Berg and Siamak Zohari, Swedish National Veterinary Institute, Sweden for providing the H5N1 influenza A viruses isolated in Sweden I also thank Prof Chan Soh Ha, NUS, ... NUS, Singapore for providing H3N2 virus- derived DNA constructs I also thank Dr Alexander N Zakhartchouk, University of Saskatchewan, Canada for providing the human adenovirus vector and Mia Brytting,...
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Understanding the adaptive immune responses against newly emerged viruses, SARS coronavirus and avian h5n1 influenza a virus 3
... two newly emerged viruses, SARS- CoV and the H5N1 influenza A virus For SARS- CoV, the focus was mainly to investigate the T cell response against the unique accessory 3a protein The study was also ... degradation of viral mRNA The IFN is also important as it enhances the efficiency of the adaptive immunity and activates the NK cells and macrophages In the case of influenza virus infection, the ... the cytoplasm, a transmembrane domain, the stalk, the head with the catalytic active site (Varghese et al., 19 83) The role of NA in the influenza virus life cycle is still unclear NA can catalyze...
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Báo cáo y học: "The role of leptin in innate and adaptive immune responses" doc
... an inflammatory challenge by altering production of proinflammatory and anti-inflammatory cytokines and may also affect cytokine signaling by a variety of mechanisms, including induction of SOCS-3 ... adipocytokines have been observed in a variety of inflammatory conditions (reviewed in [27]) and, in particular, the role of leptin in immune responses and inflammation has lately become increasingly ... signalling-3 inflammatory and anti-inflammatory factors, including adipocytokines, such as leptin, adiponectin and resistin, as well as cytokines and chemokines Altered levels of different adipocytokines...
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Báo cáo y học: "Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV" pps
... this article as: Whitney et al.: Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of ... demonstrated that oral inoculation of live attenuated Lmdd and i.v D-ala administration was safe and well tolerated in rhesus macaques Liver toxicity secondary to bacterial invasion can be a serious ... monkeys, indicating limited bacterial invasion into the liver, or complete clearance, by days after boost vaccination Our pilot results warrant the testing of attenuated Lm vectors as part of an...
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Báo cáo khoa học: " Host Immune Responses Against Hog Cholera Virus in Pigs Treated with an Ionized Alkali Mineral Complex" pot
... Responses Against Hog Cholera Virus in Pigs Treated with an Ionized Alkali Mineral Complex 317 Ta ble Proportional comparison of porcine leukocyte subpopulations in pigs treated with ionized alkali mineral ... against a virulent strain of hog cholera virus among the groups (data not shown) Host Immune Responses Against Hog Cholera Virus in Pigs Treated with an Ionized Alkali Mineral Complex 319 Acknowledgement ... persistence in the leukocytes after hog cholera virus infection might be altered, resulting in the most important features in the pathogenesis of hog cholera in pigs Pathogenic mimic of hog cholera virus...
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Báo cáo y học: "CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan–polysaccharide complexes of Gram-positive bacterial cell walls" docx
... components of Gram-positive bacterial cell walls [31] The peptidoglycan moiety is responsible for the pathogenicity of PG-PS, because enzymatic digestion of the peptidoglycan moiety eliminates the proinflammatory ... previously described in this model [22] (i.e the infiltration of inflammatory cells into the synovium, synovial hyperplasia, and fibrinous deposits; Fig 5a) Infiltration of inflammatory cells was ... necrosis factor (TNF)-α [8,10] It is less clear which primary events and cellular receptors mediate the innate immune responses to and the arthritopathogenic properties of PG-PS The intracellular...
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Báo cáo y học: "Antigen-presenting particle technology using inactivated surface-engineered viruses: induction of immune responses against infectious agents" pptx
... engineered particles did not induce antibody responses to any of the tested antigens Functional assays illustrating surface-engineered Influenza-based particle induction of cross-strain antibody formation ... HSV-2 particles (Fig 4B) The third immune assay monitored the ability of surfaceengineered non -infectious viral particles to induce specific viral antibody responses With the exception of HIV surface-engineered ... ability of influenza-based particles to induce influenza-specific antibody responses Using assays similar to those described for detecting HSV-2 specific antibody induction, PBLs exposed to surface-engineered...
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Báo cáo sinh học: "Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 ± IL-15" pdf
... by SV (gp120) -immune populations from gp120- expressing P815 cells] minus [c.p.m 51Cr released by SV(HBS )immune lymphocytes from gp120- expressing P815 cells]}, divided by [c.p.m 51Cr released by ... responses in an effort to generate immune responses against the HIV-1 envelope glycoprotein, gp120 We also tested whether co-immunization regimens involving rSV40 delivery of both IL-15 and gp120 ... Tag-deleted rSV40 vectors (unlike wild type SV40) , capsid proteins are not expressed, immune responses can only be generated by transgene products [11,12] Whether for this or for other reasons, rSV40 vectors...
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Báo cáo sinh học: " Roles of adjuvant and route of vaccination in antibody response and protection engendered by a synthetic matrix protein 2-based influenza A virus vaccine in the mouse" pdf
... 22:477-481 Asanuma H, Aizawa C, Kurata T, Tamura S: IgA antibody- forming cell responses in the nasal-associated lymphoid tissue of mice vaccinated by intranasal, intravenous and/ or subcutaneous administration ... peptide vaccine that contains ectodomains of matrix protein Vaccine 2003, 21:2616-2626 Slepushkin VA, Katz JM, Black RA, Gamble WC, Rota PA, Cox NJ: Protection of mice against influenza A virus challenge ... long lasting resistance against IAV infection, independent of the glycoprotein makeup of circulating IAV strains The ectodomain of matrix protein (M2e) is a promising candidate for a broadly protective...
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Báo cáo hóa học: " A broad spectrum, one-step reverse-transcription PCR amplification of the neuraminidase gene from multiple subtypes of influenza A virus" pdf
... samples from allantoic from all NA One-step RT -PCR amplification of NA gene from all NA subtypes using animal samples from allantoic fluids A fragment of approximately 253 bp was amplified using ... representation of 3,337 available sequences in the NCBI database at the time the study was conducted All NA subtypes were aligned against the NA10R primer and analyzed for discrepancies at the 3'end The ... [32-34] The percentage of samples with identical matches at all five 3' terminal bases was calculated for each NA subtype Figure NPA samples One-step RT -PCR amplification of NA gene from clinical One-step...
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Báo cáo y học: " Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins" ppt
... to analyse any differences between the PDZ- binding activities of the human and avian NS1 proteins A PDZ array assay had previously been reported, using a large number of isolated PDZ domains, and ... Human (H) NS1, together with the non -PDZ- binding mutant of Avian NS1 (Aa), plus the avian human-like (Ah) and the human avian-like (Ha) mutants Lower panel GST pulldown assay using these NS1 ... mutant of Avian NS1 (Aa) B GST-pulldown assay, using the NS1 proteins shown in panel A C Histogram showing the collated results of at least such assays Mapping the the PDZ domain of Dlg targeted...
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Báo cáo khoa học: " From where did the 2009 ''''swine-origin'''' influenza A virus (H1N1) emerge?" docx
... Ireland, and one each in Argentina, Indonesia and Japan In the outbreaks in Argentina, Australia and Canada, at least, the pigs had not been vaccinated (Jorge H Dillon, J Keenliside and Alain Laperle, ... reassortant parent are in blue, those from the Eurasian 'avian-like' swine virus lineage in red The black triangles indicate the mean and standard deviation of the values for the triple reassortant and ... one from Europe and the third from Asia 4) the parental genes were last sampled more than a decade ago Two were sampled around 11 years ago, the third 17 years ago, whereas their sister and cousin...
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Từ khóa: the adaptive immune systemhow innate and adaptive immune responses maintain healthkappa b rel proteins and the humoral immune responses of drosophila melanogasterstress and the adaptive immune response to hsvreceptors cytokines innate immunity and establishment of the adaptive immune responsedendritic cells and their role in linking innate and adaptive immune responsescoli based rtb p24 induced strong immune responses against p24 hiv2 understanding the two step analysis of relating stresses to external forces and momentsinfluenza a virus multiplication and the cellular sumoylation systemobjective by the end of the lesson students will be able to write simple sentences and combine them into a short text about a picnic to the countrysidethe aims and objective by the end of the lesson students will be able to write simple sentences and combine them into a short text about a picnic to the countrysideunderstanding the backlash against affirmative actionunderstanding the immune systemcruzi from the immune responsesh1 pd 1 interaction in the suppression of immune responsesBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ