receptors cytokines innate immunity and establishment of the adaptive immune response
Báo cáo y học: " The role of the humoral immune response in the molecular evolution of the envelope C2, V3 and C3 regions in chronically HIV-2 infected patients" pdf
... isolated the viruses and quantified the antibody responses HB and CR participated in virus isolation and in the sequencing analysis of some patients MD, FA and FM recruited the patients and were ... responsible for collecting the blood samples and the clinical data PG quantified the plasma viremia CN and PG helped with the interpretation of data and revision of the manuscript PB and NT preformed statistical ... at 405 and 492 nm against a reference wavelength of 620 nm The clinical cut-off value of the assay, calculated as the mean OD value of HIV-seronegative samples plus three times the standard deviation...
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Understanding the adaptive immune responses against newly emerged viruses, SARS coronavirus and avian h5n1 influenza a virus 1
... facilities in the Department of Microbiology, Tumor and Cell Biology, Karolinska Institute For the collaboration work on SARS memory T cell response, I would like to thank Prof Antonio Bertoletti and his ... Bertoletti and his lab members from the Singapore Institute of Clinical Sciences for all the help and guidance and Dr Leong Hoe Nam and Dr Ling Khoon Lin from the Singapore General Hospital for ... performing the HLA typing of the SARS individuals To all fellow laboratory members, past and present, in the Collaborative Anti-Viral Research group from the Institute of Molecular and Cell Biology,...
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Understanding the adaptive immune responses against newly emerged viruses, SARS coronavirus and avian h5n1 influenza a virus 2
... (SARS-CoV) and the H5N1 influenza A virus Together with innate immunity, the host adaptive immune responses are crucial for the clearance of the virus during an infection In the first part of this ... humoral and T cell responses in the mouse model This was followed by the production of mAb 9F4 using the rHA MAb 9F4 binds both the denatured and native forms of HA and recognizes the HA proteins of ... CD8+ T cell responses 77 Representative data of the cytokine profile of CD4+ T cell response stained with Th1/Th2 cytokines 80 Representative data of the cytokine profile of CD4+ T cell response...
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Understanding the adaptive immune responses against newly emerged viruses, SARS coronavirus and avian h5n1 influenza a virus 3
... vector Once inside the body, the next line of defense will be the host immune system which can be divided into two arms, the innate and the adaptive immunity The innate immune response is non-specific ... M and N, and the set of accessory proteins (namely ORF 3a, 3b, 6, 7a, 7b, 8a, 8b and 9b) The surface S protein is involved in the attachment and entry of the host cell The N together with M and ... It is often a race between the virus and the host’s immune system at the early stage of a viral infection There are several important players that constitute the innate immunity, the IFN response, ...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt
... perform immune functions This mechanism leads to activation of phenoloxidase, which oxidizes catechols, leading to the formation of toxic quinones and melanin [1,2], and to the activation of cytokines ... markers are indicated on the left of Spatzle-C108 (Fig 8A) Analysis of tryptic peptides ¨ from these bands by MS ⁄ MS and mascot software identified them as attacin-1, lysozyme, and cecropinA ⁄ B (Table ... with higher rates of adaptive evolution than most other genes in the genome For example, persephone, spirit, Toll and necrotic in the Toll pathway, and Imd, Dredd and Relish in the Imd pathway,...
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Báo cáo sinh học: " Open Access Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells" docx
... features of the RNA pol I promoters and rRNA genes from other mammalian species In the genomes of human, mouse and rat, the distance from the beginning of the 18S rRNA sequences to Page of 12 (page ... released into the cytoplasm and subsequently enter the nucleus where replication of the vRNA results in the production of both mRNA and complementary RNA (cRNA), the template for synthesis of more ... because the former restriction site occurs in the MDCK pol I containing fragment isolates of the H6N1, H7N3 and H9N2 subtypes (Table 2) The wt virus which was the source of the HA and NA for the...
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Báo cáo hóa học: " Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells" pdf
... features of the RNA pol I promoters and rRNA genes from other mammalian species In the genomes of human, mouse and rat, the distance from the beginning of the 18S rRNA sequences to Page of 12 (page ... released into the cytoplasm and subsequently enter the nucleus where replication of the vRNA results in the production of both mRNA and complementary RNA (cRNA), the template for synthesis of more ... because the former restriction site occurs in the MDCK pol I containing fragment isolates of the H6N1, H7N3 and H9N2 subtypes (Table 2) The wt virus which was the source of the HA and NA for the...
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Báo cáo nghiên cứu khoa học " ESTABLISHMENT OF THE GLOBALGAP SYSTEM FOR DRAGON FRUIT FAMERS AND EXPORTER IN THE SOUTHERN PROVINCES " pptx
... them to approach and comply with the standards before the auditing of certify body The selected Implementation of GAP on farm by project experts with farmers 3.4 Certification and expanding the ... model, meeting to the quality manual and needed standards; Specification of position in the process and assumption the responsibility as the position description stated in the in the quality manual; ... programme and therefore the improvement of rural life standards is indispensable The enhancement of national capacity both in public and private sectors through practical implementing of GAP is...
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Báo cáo y học: "The role of leptin in innate and adaptive immune responses" doc
... is a part of the cytokine cascade, which orchestrates the innate immune response and host defense mechanisms [28,29] Like other members of the IL-6 family, leptin was shown to activate the Janus ... versus innate immune responses: adaptive immune- mediated responses are attenuated, whereas in models involving the innate immune response, leptin deficiency causes inadequate control of inflammation ... responses: adaptive immune- mediated responses are attenuated whereas, in experimental models involving the innate immune response, leptin deficiency causes inadequate control of the inflammatory response...
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Báo cáo y học: "The proinflammatory cytokines IL-1β and TNF-α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway" ppt
... starved and then cultivated in the presence of 10 ng/ml of IL-1β or TNF-α without or with SN50 for 24 hours The expression of SYN in these cells was analyzed by Western blotting (top panel), and the ... arrest the cell cycle of these synovial fibroblasts from either normal DBA or CIA mice (Figure 6c) These findings suggest that the activation of Erk and ETS1 is involved in the overgrowth of mouse ... growth response- 1), and NF-κB, in synovial fibroblasts Activation of the NF-κB/Rel transcription family and AP1 complexes, composed of members of the Jun and Fos families, contributes to the hyperproliferation...
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Báo cáo y học: "Bench-to-bedside review: Biotrauma and modulation of the innate immune response" pps
... body of evidence in support of the theory that mechanical ventilation may sensitize the innate immune system and that, in turn, the innate immune system may sensitize the lungs to the effects of ... biologic and clinical implications VILI can modulate polymorphonuclear neutrophil function and innate immune response to lipopolysaccharide and sepsis The general strategy of innate immune detection ... leading to activation of the β2 receptors on cells of both myeloid and nonmyeloid origin, resulting in the downregulation of proinflammatory cytokines and upregulation of anti-inflammatory mediators...
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Báo cáo y học: " The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns" ppsx
... with the neoplastic nature of the cells [11], and suggests the presence of both fully differentiated hepatocytes and progenitor cells in the cHCC cell culture The hepatocytic nature of the cHCC ... liver tissue of healthy dogs, measured by quantitative Real-Time PCR Data represent mean ± SE of the groups The "n" for these figures stands for the fold change of the gene expressions of the cell ... definitive proof of the hepatocytic and neoplastic nature of the cHCC cells Positive staining for hepatocyte marker HepPar1 strongly indicates the hepatocytic origin of the cultured cells [10] The neoplastic...
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Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... case of MZ with mirror-imaging of AC in the literature In this case, we describe the second case of MZ with mirror-imaging of AC and discuss the possible clinical implications First, Helland and ... lack of systematic monitoring and follow-up Therefore, a large percentage of patients with AC are probably undiscovered Mirror images, on the other hand, are present in approximately 25% of MZ Therefore, ... consider that it is mandatory to monitor the counterpart of the symptomatic patient with AC as early as possible, irrespective of the absence of symptoms Conflict of Interest The authors have declared...
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Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"
... craniotomy because of the proximity of the sinus to the orbit and the anterior skull base [5] The frequency of bilateral absence of the frontal sinus has been reported in 3-4% to 10% of several populations ... reliability between observers and was 0.86 Fig Unilateral absence of the frontal sinus; on the right, the absence of the frontal sinus, and on the left, the limited aeration of the frontal sinus; axial ... sinuses, although there is only one frontal sinus ostium The size of the sinus and, therefore, its anatomic relationships also depend upon the extent of pneumatization [11] The extent of pneumatization...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... by the local Ethics Committee of Taizhou Municipal Hospital, and had the informed consent of the patients and volunteers The patients and serum samples were then divided into two groups: the ... between the groups of colorectal cancer and healthy controls, these data in the Excel format were imported into the Biomarker Pattern Software (BPS) to construct the classification tree of CRC The ... calculated as the ratio of the 42 number of correctly classified diseased samples to the total number of diseased samples Specificity was calculated as the ratio of the number of negative samples...
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Báo cáo y học: " Post-traumatic glioma: Report of one case and review of the literature"
... occurrence of the tumor corresponded exactly one to the other; and (4) there was a more than one year interval between trauma and the appearance of the tumor As regards the pathogenesis of post-traumatic ... time interval between trauma and the appearance of the tumor of at least year, a longer latent period increasing the likelihood of a causal relationship The presence of the tumor must be proved histologically ... at the time of the trauma demonstrating significant injury and the follow-up scans demonstrating tumor at the same site4 With the routine use of CT and magnetic resonance imaging (MRI), some of...
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. Scope and Limitations of the Study
... circumstances In the resolutions of the VIth and the VIIth congresses of the Communists Party and those of the important meeting of the National Assembly, the Government and the Central Party ... assessment the demand of skilled labor and how to solve the gap between demand and supply of skilled labor for sustainable economic growth in Vietnam Objectives of the Study The objectives of the study ... building up the whole system It is hoped that these schools (10-15% of the sector) will reach the standards of the best institutions in the region and gradually those of the world While these school...
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Scope and Limitations of the Study
... component of most management definitions of strategy Strategy is the determination of the basic long-term goals and objectives of an enterprises, and the adoption of courses of action and the allocation ... features 60 As a rule, then, the lower the price of substitutes, the higher the quality and the performance, and the lower the user’s switching costs, the more intense are the competitive pressures ... market conditions in the supplier industry and the significance of the item they supply The competitive fore of suppliers is greatly diminished whenever the item they provide is a standard commodity...
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Methodology and framework of the study
... including the rationale of the study, the identification of the problem, the objectives, the scope and limitations as well as the methodology and framework of the study Chapter shows the literature ... 2000 and 80% by 2005 • To improve the quality of plastic products to meet the demand of high quality consumer products of the country, then to increase the quantity and expand varieties of export ... simplified, the level of knowledge of the management organizations and officers in charge of investment are now improved The consolidation of the former SCCI and SPC into one Ministry, which is now the...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008