Intra cellular endoplasmic reticulum dynamics, distribution and function in response to cell engineered surface adhesion

... α-actinin with integrin; green lines indicate the binding of talin, α-actinin and vinculin with actin filaments; and blue lines indicate the binding of vinculin with talin and α-actinin The indirect ... of integrins to actin cytoskeleton via the recruitment of interacting cytoskeletal proteins including talin, vinculin and α-actinin (Ziegler et al., 2008) Integrin β subunit binds t...

Ngày tải lên: 11/09/2015, 09:02

... Discussion The main finding of this study is the identification of a metabolic gene switch from fatty acids to glucose in the murine female heart at baseline linked to enhanced mitochondrial respiratory ... al Metabolic gene switching in murine female heart function [8] Likewise, high fatty acid oxidation rates in the diabetic heart results in...

Ngày tải lên: 18/02/2014, 16:20

... http://www.biomedcentral.com/1471-2229/6/23 Figure Expression of apple PR genes in response to inoculation with plant pathogenic bacteria Expression of apple PR genes in response to inoculation with plant pathogenic bacteria ... PR- 8 following inoculation of apple shoots with Erwinia amylovora by three different methods Figure Expression of P...

Ngày tải lên: 12/08/2014, 05:20

... brings the total known number of kinectin isoforms in mouse to 16 (Fig 1.2) The identification of total of 16 kinectin isoforms reveals the long-suspected existence of a family of kinectin isoforms ... kDa kinectin of Int4 at the leading edge of migrating cells 60 Chapter Roles of kinectin Int4 in ER dynamics during cell migration and division 63...

Ngày tải lên: 08/11/2015, 16:45

... C-terminal His6-tag impaired retention of pFGE, indicating that the C-terminus of pFGE might be involved in the ER retention mechanism pFGE carries canonical or noncanonical ER retention signals in ... 1121 ER retention by noncanonical retention signals S L Gande et al form of pFGE was secreted during the pulse, and most of these forms were retained i...

Ngày tải lên: 23/03/2014, 07:20

... protein response genes in Arabidopsis vesicle trafficking ⁄ transport, vacuolar protein sorting, cell wall biogenesis, and lipid ⁄ inositol metabolism In comparison with those of yeast, the UPR genes ... analysis In addition to the genes related to protein folding and degradation, genes related to protein translation and apoptosis are also included in the list Results Fluid m...

Ngày tải lên: 07/03/2014, 21:20

... reproductive strategies within coleoid cephalopods and for developing a general scale for maturity staging for males and females Materials and Methods Details of the structure of the reproductive system ... in Cephalopods TABLE A general scale of maturity stages for male and female cephalopods (AG gland, SP = spermatophore, SOC = spermatophoric...

Ngày tải lên: 14/03/2014, 16:20

... Cite this article as: Bonanno et al.: Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies Journal of Translational Medicine 2010 8:114 Submit ... implication of our findings pertains to HLA-matched stem cell transplantation, a clinical context where pegfilgrastim administration may modulate the number o...

Ngày tải lên: 18/06/2014, 16:20

... species in 68-years old pure jack pine stands, stands mixed with aspen and stands mixed with white birch The spatial distribution of trees in jack pine stands mixed with aspen shows that jack pine ... repulsion is present only on one stand Table II Effect of stand type on skewness of basal area distribution of the three main tree species in p...

Ngày tải lên: 08/08/2014, 01:21

... processed with Lysis II software (BD Biosciences) To determine leukocyte and lymphocyte numbers, 130 μl of whole blood was aspirated and analyzed using a hematology analyzer CELL- DYN 3500SL (Abbott ... LCPUFA levels in erythrocyte membranes and LT production by lymphocytes The discrepancy in the pattern of regression – that is, linear in the case of LT or U-shaped in th...

Ngày tải lên: 09/08/2014, 10:23

... function in a legal system – a general study This book addresses three major questions about law and legal systems: (1) What are the defining and organizing forms of legal institutions, legal rules, interpretive ... overall forms of functional legal units, and on the overall form of a legal system as a whole, as major avenues for advancing understanding...

Ngày tải lên: 09/08/2014, 11:20

... functional legal units, and (6) in integrating and coordinating such units within a duly systematized operational system Form and the formal in functional legal units, and in a legal system as a whole, ... in 22 23 24 OED, supra n 2, vol 6, at form I.13; id., vol 6, at “formal” A. 3 .a P Atiyah and R Summers, Form and Substance in Anglo-American...

Ngày tải lên: 09/08/2014, 11:20

... units and the performances of participants in the system? What roles forms play in the systematization of a legal system as such? How can an understanding of forms cast light on the general nature ... interpretation A form- oriented approach is oriented to the dynamic, integrative, and systematized nature of law-making and law-implementing activities that always involve...

Ngày tải lên: 09/08/2014, 11:20

... arbitrary They call for identifying and articulating reasons for and against alternative choices of form and content, and for the weighing and balancing of such reasons The overall form of a statutory ... of pre-emptoriness, see P Atiyah and R Summers, Form and Substance in Anglo-American Law: A Comparative Study of Legal Reasoning, Legal Theory, and Legal...

Ngày tải lên: 09/08/2014, 11:20

... scrutinizing, debating, amending, and adopting a statute Such drafting also facilitates learnability of the law and the pre-emptoriness of those legal reasons for determinate action that arise for addressees ... reinforcive and regulative The Purpose of Creating and Maintaining Discrete Functional Legal Units and a Legal System as a Whole Without resort to the overall...

Ngày tải lên: 09/08/2014, 11:20