The role of b cells in the pathogenesis of atherosclerosis 1

... demonstrate the presence of such opposite changes in the responsiveness of the airway and tissue compartments in the presence of oxygen toxicity Indeed, expression of the hyperoxia-induced changes in the ... in larger mammals [9,45] and in mice [46] Conclusion In summary, the results of the present study yield evidence of the involvement of ET-1 in the lung function changes induced by hyperoxia The ... stimuli In fact, the apparent hyperreactivity of the lung is attributed to the presence of the enhanced responsiveness of the lung parenchyma and not to the elevated reactivity of the airways As...

... 11 6 11 9 4 .1 The role of Annexin- 1 in the regulation of inflammatory stress 11 9 response 4.2 Conclusion 14 4 4.3 Limitations of the study 14 5 4.4 Future work 14 6 Bibliography 14 8 Summary Annexin- 1 ... for investigation of the basis of the inflammatory stress response The aims of this study are thus, 1) To determine the role of ANXA1 in the regulation of the inflammatory response upon induction ... (ANXA1) 27 1. 6 .1 Functions of ANXA1 29 1. 6 .1. 1 ANXA1 in inflammation 29 1. 6 .1. 2 ANXA1 in cellular proliferation, differentiation and apoptosis 31 1.6 .1. 3 ANXA1 in cancer 33 1. 6 .1. 4 ANXA1 in leukocyte...

... function upstream of the effector caspases in apoptosis and are known as initiator caspases A phylogenetically distinct group of 13 caspases (caspase- 1, caspase- 4, caspase- 5, caspase- 11 and caspase- 12 ) ... caspase- 1 to an influenza A/ Puerto Rico/8/34 (H1N1) virus infection of RAW264.7 murine macrophages, in vitro To investigate the role of caspase- 1 in pulmonary inflammation and cell death and its contribution ... known as PYCARD, which consists of an N-terminal PYD domain and a C-terminal caspase activation and recruitment domain (CARD) that is necessary for the binding of caspase- 1 to the inflammasome (Martinon...

... because of the risk of EPS by antipsychotic drugs More detailed double-blind studies should be performed to clarify the role of sigma-1 receptors in the efficacy of fluvoxamine for psychotic ... involved in the active mechanisms of fluvoxamine [5] Based on all these findings, a hypothesis has been proposed that the sigma-1 receptors may be implicated in the efficacy of fluvoxamine for psychotic ... receptors in the pathophysiology of neuropsychiatric diseases J Receptor Ligand Channel Res 2010, 3:25-36 [http://www.dovepress.com /the- role- ofsigma-1-receptors-in -the- pathophysiology -of- neuropsychiatr-peerreviewed-article-JRLCR]...

... Figure Memory4< /b> B cells in peripheral blood Memory < /b> B cells in peripheral blood A) Percentages of < /b> memory < /b> B cells and class switched memory < /b> B cells (D) in peripheral blood of < /b> current smokers (closed symbols) ... Flow cytometry plots of < /b> B cells and memory < /b> B cells in peripheral blood Flow cytometry plots of < /b> B cells and memory < /b> B cells in peripheral blood A representative example of < /b> the difference in percentage ... peripheral blood B cells in peripheral blood A) Percentages of < /b> total B cells in peripheral blood of < /b> COPD patients (closed symbols) and healthy individuals (open symbols) The result of < /b> the multiple linear...