Studying multicellular dynamics with single cell micropattern clusters

... effects of cell shape and cell- matrix adhesion …… … 23 2.2.1.4 Cell- cell interactions ………………………………… ……… … 24 2.2.2 Effect of cell geometry and connectivity on single cell functions 2.2.2.1 Cell proliferation ... understanding how cell- cell interactions can affect cell behavior With an excellent physical control of the geometry, adhesion and arrangement of single cells, s...

Ngày tải lên: 09/09/2015, 11:30

... Soria JC, Le Chevalier T, Pignon JP: Benefits of adding a drug to a single- agent or a 2 -agent chemotherapy regimen in advanced non- small- cell lung cancer: a meta-analysis JAMA 2004, 292:470-84 Mattson ... complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lu...

Ngày tải lên: 09/08/2014, 03:21

... and (e) 435 after the inoculation To measure the localization -dynamics of expressed proteins and the motility of single cells simultaneously, we used the on-chip microcultivation system and assayed ... when bacterium was stimulated by aspartate Dashed lines show bacterial division points after 80 of stimulation by aspartate, localized Tar was diffused completely Then...

Ngày tải lên: 11/08/2014, 00:22

... time-dependent mRNA expression of single living cells, but it is limited to the analysis of the fine localization of mRNA in the cells ISH can examine mRNA expression of the whole cells with higher resolution, ... (In/ I0) I0 is the average of the background intensity In is the darkness intensity of each point of the cell In this equation, we con...

Ngày tải lên: 11/08/2014, 00:22

... collective, and the interactions of molecules and forces which can bring about the motion of cells 1.5.1 Part I: Investigating actin dynamics in circular dorsal ruffles In the first study, the phenomenon of ... behaviour in collective cell migration shows that single cell migration, although the driving force behind collective cell migration, is unable to f...

Ngày tải lên: 09/09/2015, 18:51

... Single cell protein concept  Single cell protein is a terms for a type of cell nutrient and it produced by microorganisms  Microbial species capable of single cell protein synthesis ... disadvantages Advantages of single cell protein: • Disadvantages of • Protein in high cell • Slow digestion by the cell structure • • Good quality protein • Safety toxins si...

Ngày tải lên: 03/01/2013, 12:52

... descriptive method to investigate the parental attitude towards children with sickle cell disease in selected health facilities in Irepodun Local Government Area of Kwara State, Nigeria Population ... causes of sickle cell disease and their attitudes toward children with sickle cell disease Table 2: Relationship of sex and attitude of the...

Ngày tải lên: 12/02/2014, 19:20

... HIV enters the cells following virus binding to CD4 and co-receptors and the fusion of the viral membrane with the plasma membrane of the cell During passage through the cytosol, the viral RNA ... Conclusions In the past few years, numerous studies of virus host interactions have revealed the role of the dynein motor and the integrity of microtu...

Ngày tải lên: 14/03/2014, 22:20

... bioavailability of PNA after conjugation with natural CPPs [3–8], an almost one order of magnitude higher intracellular PNA concentration was achieved after exposing cells to the MAP PNA conjugate ... Oehlke et al (Eur J Biochem 271) Table Sequences of the PNA derivatives studied Compound Sequence MAP I KLALKLALKALKAALKLA-NH2 Fluos-GGAGCAGGAAAG-Lys (antisense) Fluos-G...

Ngày tải lên: 23/03/2014, 13:20

... net rate of binding of Ca2+ to the j-th class of Ca2+ buffer (e.g protein); vd, degradation of IP3 (performed mainly by hydrolysis to inositol1,4-bisphosphate or phosphorylation to inositol-1,3,4,5-tetrakisphosphate); ... is the ryanodine receptor (RyR), whose physiological activator appears to be cyclic ADP ribose [44] Opening of the IP3R, in the presence of IP3, and of...

Ngày tải lên: 24/03/2014, 00:21

... Ribas et al.: Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma Journal of Translational Medicine 2010 8:89 Submit your ... Dacarbazine (DTIC) versus vaccination with autologous peptide -pulsed dendritic cells (DC) in firstline treatment of patients with metastati...

Ngày tải lên: 18/06/2014, 16:20

... determining discriminant validity of the PedsQL™ Family Impact Module in our population of children with sickle cell disease, we collected data on the disease status of the children with sickle cell ... and reliable measure for assessing the impact of SCD on parents and families We therefore analyzed the following properties of the PedsQL™...

Ngày tải lên: 18/06/2014, 18:20

... Hydroxyurea and sickle cell anemia: effect on quality of life Health & Quality of Life Outcomes 2006, 4:59 Maikler VE, Broome ME, Bailey P, Lea G: Children's and adolescents' use of diaries for sickle cell ... Psychosocial Adaptation of Children and Adolescents With Sickle Cell Disease In Comprehensive handbook of childhood cancer and sickle cell...

Ngày tải lên: 18/06/2014, 19:20

... least one gene should be altered in both forms This has been confirmed with the cloning of the VHL gene and the identification of germline and somatic mutations of this gene in VHL patients and sporadic ... analysis of VHL without mutation detected in this gene, suggesting that other genes may be implicated in RCC and in particular linked t...

Ngày tải lên: 20/06/2014, 00:20

... Cite this article as: Hijmans et al.: Double disadvantage: a case control study on health-related quality of life in children with sickle cell disease Health and Quality of Life Outcomes 2010 ... double disadvantage: a chronic disease, on top of an unfavourable background Declaration of competing interests The authors declare that they have no...

Ngày tải lên: 20/06/2014, 15:20