Dynamic mechanical stimulation for mesenchymal stem cell chondrogenesis in an elastomeric scaffold

... Wu Yingnan, Antony J DenslinVinitha, Deepak Raghothaman, Afizah Hassan and Ren Xiafei Thanks to Eriza Amaranto in NUS Tissue Engineering Program, for his good administration I am thankful for ... Mechanotransduction in Cartilage Repair There has been a growing interest in understanding the mechanotransduction mechanism of how physical stimulation is transduced into biological sign...

Ngày tải lên: 09/09/2015, 08:12

... Nardi NB: In search of the in vivo identity of mesenchymal stem cells Stem Cells 2008, 26:2287-2299 Caplan AI, Bruder SP: Mesenchymal stem cells: building blocks for molecular medicine in the 21st ... batched) by cytospins and direct cell counts [33] BAL level of cytokines (R&D Systems, Minneapolis, MN) were assessed by ELISAs and Luminex multiplex assays as previously descr...

Ngày tải lên: 11/08/2014, 03:20

... bone marrowderived mesenchymal stem cells and osteoblast differentiation on titanium with surface-grafted chitosan and immobilized bone morphogenetic protein-2, 2nd International Congress on Stem ... immobilized bone morphogenetic protein-2 Introduction 66 Materials and methods 67 Results 72 Discussion 86 Conclusion 89 Chapter Human 91 bone marrow-derived mesenchymal stem cell...

Ngày tải lên: 14/09/2015, 08:37

... u/con Lô ung thư hóa 10 80 19 2,37 ± 0,32 Lô ung thư hóa & Tế bào gốc 33,3 2,00 ± 0,58 Thí nghiệm Kết phân tích thống kê cho thấy, nhóm chuột có sử dụng tế bào gốc trung mô liều 107 tế bào/ ml có ... bào gốc có số lượng khối u ác tính so với nhóm không sử dụng tế bào gốc Có chuột có u ác tính tổng số 10 chuột thí nghiệm lô chuột gây ung...

Ngày tải lên: 20/03/2014, 09:21

... as: Chen et al.: Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction Journal of Translational ... adipose-derived mesenchymal stem cells (ADMSCs) After culturing for 14 days, majority of isolated adipose-derived stem cells expressing CD29 and CD90 character...

Ngày tải lên: 18/06/2014, 19:20

... article as: Tsai et al.: Overexpression of hTERT increases stemlike properties and decreases spontaneous differentiation in human mesenchymal stem cell lines Journal of Biomedical Science 2010 ... such as Oct4 and Nanog is associated with differentiation of neural stem cells, hematopoietic stem cells and MSCs However, an increase in Oct4 expressio...

Ngày tải lên: 10/08/2014, 05:21

... cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells Journal of Biomedical Science 2011 18:54 Submit your next manuscript ... transplantation of hMSCs via tail vein could ameliorate the deterioration of motor function in SCA2 transgenic mice Rescue of Purkinje Cells by Transp...

Ngày tải lên: 10/08/2014, 10:20

... to the extracellular matrix, the degradation of the extracellular matrix by the proteinase secreted by the tumor cells, and the transfer and proliferation of tumor cells[36] So, the loose of ... article as: Xishan et al.: The research on the immunomodulatory defect of Mesenchymal Stem Cell from Chronic Myeloid Leukemia patients Journal of Experi...

Ngày tải lên: 10/08/2014, 10:21

... mesenchymal stem cells; HD: hematopoietic differentiated cells; AIDS: acquired immune deficiency syndrome; HAART: highly active anti-retroviral therapy; HPCs: hematopoietic progenitor cells; ... established as to how these mesenchyme derived cells become susceptible to HIV-1 and whether their HIV-1 production rates are comparable to that observed in HIV-1 infected l...

Ngày tải lên: 13/08/2014, 01:20

... protection pathways in APAP- and H2O2 -induced liver injury in TAMH cells 156 Figure 44 Combination therapy of exosomes and -T3 in APAP- and H2O 2induced liver injury in TAMH cells ... virally -induced disease predominated in early 90s but has substantially declined in the past few years, with most acute injury cases now arising from drug induced- liver...

Ngày tải lên: 09/09/2015, 11:21

... of stem cells is a promising method for cartilage repair, in this chapter I confirmed that engraftment of the MSCs in injured cartilage is an active migration and homing process and injured cartilage ... microfracture (265, 266), or introducing new cell sources like debrided waste chondrocytes, Bone Marrow derived Mesenchymal Stem Cells (BM MSCs), or any combinati...

Ngày tải lên: 10/09/2015, 09:01

...   1. 5 Types of stem cells 14   1. 5 .1 Embryonic stem cells (ESCs) 15   1. 5.2 Induced pluripotent stem (iPS) cells 15   1. 5.3 Adult stem cells 16   1. 5.4 Heterologous stem cells 17   1. 6 MSCs in ... 1. 10.3 Iron Oxide Particles 24   1. 11 Cellular MRI 24   1. 11. 1 Cellular Imaging with Iron Oxide Particles 25   1. 11. 2 Mechanisms of Cellular Uptake 28   1....

Ngày tải lên: 10/09/2015, 09:10

... determined using 0.3% oil red O stain for 15 minutes at room temperature to stain intracellular lipids, and counterstained with hematoxylin Osteogenic differentiation was evaluated using Alizarin ... staining of the harvested tissues (197) 55   Table 3-1 Histological grading scale for cartilage repair (Adapted from (51)) Category Points Cell morphology Hyaline cartilage Mostly hyaline...

Ngày tải lên: 10/09/2015, 09:10