a model for cochlear stem cell biology in humans

... treatment of the brain), and somatic stem cells capable of generating cell types specific for the target rather than the donor organ (e.g., bone marrow mesenchymal stem cells for cardiac repair) ... spermatogonia in the adult human testis, providing another strategy for obtaining genetically identical stem cells Umbilical cord blood stem/ progenitor cells are associated with less graftversus-host ... isolate from other tissues, such as heart and brain Substantial efforts have therefore been devoted to obtaining more pluripotent stem cell populations, such as bone marrow mesenchymal stem cells...

Ngày tải lên: 07/07/2014, 01:20

... not yet clear, and various experimental studies have employed intramyocardial, transendocardial, intravenous, and intracoronary injections In experimental myocardial infarction, functional improvements ... improvements have been achieved after transplantation of a variety of different cell types, including ES cells, bone marrow stem cells, endothelial stem cells, and adipose stem cells Bone marrow stem cells ... (Chap 65) Figure 67-1 Strategies for transplantation of stem cells Undifferentiated or partially differentiated stem cells may be injected directly in the target organ or intravenously Stem cells...

Ngày tải lên: 07/07/2014, 01:20

... abortuses are an alternative, and a clinical trial of fetal neural stem cells in Batten disease is commencing Transdifferentiation of bone marrow and adipose stem cells into neural stem cells, and ... Multipotential stem cells also reside within gastric glands and intestinal crypts Thus, hepatic, pancreatic, and/or gastrointestinal precursor cells may be candidates for cell- based therapy of diabetes ... cells in stroke are also planned Neurologic disorders that have already been targeted for stem cell therapies include spinal cord injury, amyotrophic lateral sclerosis, stroke, traumatic brain...

Ngày tải lên: 07/07/2014, 01:20

... organ Imaging techniques are needed to visualize stem cells in vivo after transplantation into humans Fortunately, stem cells can be engineered before transplantation to contain contrast agents ... extraordinary, and disorders such as myocardial infarction, diabetes, Parkinson's disease and many others are attractive targets However, such stem cell based therapies are at a very early stage ... Lanza R et al (eds): Essentials of Stem Cell Biology San Diego, Elsevier Academic Press, 2006 Mimeault M et al: Stem cells: A revolution in therapeutics-recent advances in stem cell biology and...

Ngày tải lên: 07/07/2014, 01:20

... concentration Adapted from J M Mansour, chapter 2.1.3 Articular Cartilage Damage Damage to articular cartilage can occur from trauma, disease, aging or excessive mechanical loading Cartilage lesions ... characterization and bioreactor operation I also appreciate the hearty support from all my colleagues Wu Yingnan, Antony J DenslinVinitha, Deepak Raghothaman, Afizah Hassan and Ren Xiafei Thanks ... and cell matrix interactions and is associated with increased cell adhesion, formation of gap junctions and changes in the cytoskeletal architecture (Stains & Civitelli, 2005) activate intracellular...

Ngày tải lên: 09/09/2015, 08:12

... lavage Diagn Microbiol Infect Dis 2005, 52:275-280 Fujimaki K, Mori T, Kida A, Tanaka M, Kawai N, Matsushima T, Kishi K, Fujisawa S, Sakura T, Yokota A, Kanda Y, Taguchi J, Akiyama H, Kanamori ... transplantation Bone Marrow Transplant 2007, 39:705-709 Savolainen H, Lautenschlager I, Piiparinen H, Saarinen-Pihkala U, Hovi L, Vettenranta K: Human herpesvirus-6 and -7 in pediatric stem cell transplantation ... Marty FM, Schwartz RB: MR imaging of human herpesvirus-6-associated encephalitis in patients with anterograde amnesia after allogeneic hematopoietic stem- cell transplantation AJNR Am J Neuroradiol...

Ngày tải lên: 12/08/2014, 04:21

... lavage Diagn Microbiol Infect Dis 2005, 52:275-280 Fujimaki K, Mori T, Kida A, Tanaka M, Kawai N, Matsushima T, Kishi K, Fujisawa S, Sakura T, Yokota A, Kanda Y, Taguchi J, Akiyama H, Kanamori ... transplantation Bone Marrow Transplant 2007, 39:705-709 Savolainen H, Lautenschlager I, Piiparinen H, Saarinen-Pihkala U, Hovi L, Vettenranta K: Human herpesvirus-6 and -7 in pediatric stem cell transplantation ... Marty FM, Schwartz RB: MR imaging of human herpesvirus-6-associated encephalitis in patients with anterograde amnesia after allogeneic hematopoietic stem- cell transplantation AJNR Am J Neuroradiol...

Ngày tải lên: 12/08/2014, 04:22

... 909–913 89 Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K & Yamanaka S (2009) Suppression of induced pluripotent stem cell generation by the p53–p21 pathway Nature 460, 1132–1135 ... Zhu H, Perez-Atayde New advances in human hematopoiesis from human ESCs A, Frazier AL et al (2009) A role for Lin28 in primordial germ -cell development and germ -cell malignancy Nature 460, 909–913 ... achieving this by serial reprogramming or by treating iPSCs with chromatinmodifying chemicals has been described [85] An alternative method for avoiding problems associated with partially retained...

Ngày tải lên: 22/03/2014, 17:20

... of machine translation Pavel Pecina, Antonio Toral, Andy Way, Vassilis Papavassiliou, Prokopis Prokopidis, and Maria Giagkou 2011 Towards using web-crawled data for domain adaptation in statistical ... Online large-margin training for statistical machine translation In Proceedings of the 2007 Joint Conference on Empirical Methods in Natural Language Processing and Computational Natural Language ... Statistical Machine Translation, pages 182–189 Association for Computational Linguistics Caroline Brun, Vassilina Nikoulina, and Nikolaos Lagos 2012 Linguistically-adapted structural query annotation...

Ngày tải lên: 24/03/2014, 03:20

... War Bonds in the Second World War: A Model for a New Iraq/Afghanistan War Bond? Summary The high costs of fighting the wars in Iraq and Afghanistan have rekindled congressional interest in ... financial institutions Today, savings bonds are almost always a substitute mechanism for other forms of personal savings Author Contact Information James M Bickley Specialist in Public Finance ... Congressional Research Service War Bonds in the Second World War: A Model for a New Iraq/Afghanistan War Bond? Introduction The high costs of fighting the wars in Iraq and Afghanistan have rekindled...

Ngày tải lên: 29/03/2014, 03:20

... local savings associations, 34 regional savings banks, National Bank of the savings banks) Tripartite (519 local savings banks, 12 regional state banks, DekaBankDeutsche Girozentrale) Coordinating ... local savings companies at its disposal since 1999 These are not involved in the financial business but are closely associated with the savings banks in a legal and practical sense The local savings ... in France Although not independent institutions, they are invariably attached to the savings bank in the region in which they operate In this way, several savings companies are attached to each...

Ngày tải lên: 29/03/2014, 08:20

... dacarbazine with interferon alpha-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon alpha-2b and tamoxifen in patients with metastatic malignant melanoma: an Eastern Cooperative ... Eggermont AM: Interferon alfa- 2a and interleukin-2 with or without cisplatin in metastatic melanoma: a randomized trial of the European Organization for Research and Treatment of Cancer Melanoma Cooperative ... trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b J Clin...

Ngày tải lên: 18/06/2014, 16:20

... Integration, application and practice objectives are one area where practica and capstones (theses or projects) can serve a critical catch-all role, in much the same way as qualifying exams for ... strategic planning approach Assess and align mission The newly created Department of Health Behavior and Administration was charged with administering two existing graduate degree programmes (Master ... program graduates – Program • Define the program’s academic goals and primary objectives Specify educational strategies/approaches • Define key educational strategies and approaches needed to achieve...

Ngày tải lên: 18/06/2014, 17:20

... other, integrating extracellular signals— not shown—, regulating metabolic pathways (arrow 3), re- Feedback signals Transcription DNA Translation RNA Proteins Metabolic pathways Microarray measurements ... PGN model from available dynamical data of cell- cycle progression, analogously to what we have done for the regulatory system of the malaria parasite [5, 6] We anticipate that, very likely, analysis ... noise in the system In this mapping, binary value was mapped to 2, and binary value was mapped to 0, of the three-level model Intermediate values (in the driving and transition functions) were mapped...

Ngày tải lên: 22/06/2014, 19:20

... used in this work were collected as part of a larger project that examined patterns of below- and above-ground biomass in Eucalyptus populnea woodland ecosystems along a rainfall gradient in northeast ... was adjusted Two approaches were tested Both approaches are based on the observation that lateral root spreads generally increase with an increase in plant size [19] In the first approach, the assumed ... Ammer and Wagner [2] for predicting FRB pools in compositionally diverse woodland vegetation from contrasting climatic regions in northeast Australia MATERIALS AND METHODS 2.1 Data source The data...

Ngày tải lên: 07/08/2014, 16:20

... inference: a practical information-theoretic approach, Springer-Verlag, New York, 1998 A height-diameter model for Pinus radiata [8] Caủadas N., Garc a C., Montero G., Relaciún altura-diỏmetro para Pinus ... basal area, quadratic mean diameter, maximum diameter, dominant diameter and height (using Assman's criterion for both), mean height, age (because the stands are evenaged, the age was calculated ... specie in Galicia [35] The mean, maximum and minimum values and standard deviations of the main dendrometric and stand variables are given in table I and table II, respectively Mean Maximum Minimum...

Ngày tải lên: 08/08/2014, 01:21

... reducing the parametric nonlinearity, but we did not investigate this point in forcing us to think about those aspects of the model for which the data provide good information and those aspects for ... the dual influence of the shape parameter in this case, which partially explains the high e-correlation For this model, a variable shape parameter between curves will also lead to interpretative ... Chapman-Richards (Richards, 1959) variableshape functions Both curves have parameters, which have the following meanings: A asymptote; r= related to relative growth rate; m shape parameter; and...

Ngày tải lên: 08/08/2014, 19:21

... examine for any associations between the demographic variables and the total score of the BPRS, BSI, and Client Observation Scale General linear model (mixed model analysis of variance (ANOVA)) was ... such as when raters were available and did not interfere with the subjects' other commitments All raters had undergone the same training and testing for inter-rater reliability The raters explained ... between and 24 h from the beginning of treatment (that is, from the subject's examination by a psychiatrist and formulation of a treatment plan by the clinical team) Research assistants ('raters'),...

Ngày tải lên: 08/08/2014, 23:21

... (Miami, FL, USA) Anti-dsDNA and anti-nucleosome antibodies were obtained from Orgentec Diagnostika (Mainz, Germany) ELISA was performed in accordance with the manufacturer's instructions All assays ... Houssiau FA, Ramirez G, Baguley E, McCutcheon J, Vianna J, Haga HJ, Swana GT, Khamashta MA, Taylor JC: Antibodies to endothelial cells in systemic lupus erythematosus: a potential marker for nephritis ... Mimori A, Takeda A, Minota S, Kano S: Quantification of antiribosomal P0 protein antibodies by ELISA with recombinant P0 fusion protein and their association with central nervous system disease in...

Ngày tải lên: 09/08/2014, 01:23

... particular individuals in a stand Sap flow data have been used for estimating hourly transpiration and canopy conductances in a range of forest stands [1, 10, 13, 19, 20] The sap flow measurements can ... on each site ’upscaled’ the sap flux values from tree to stand using optically determined leaf area index values (table I), assuming the needles had a semi-cylindrical shape, and calculating ... resisand capacitances are expressed on an all-sided needle area basis The water potential values used in the present paper are corrected for the gravitational gradient The basic equations for each...

Ngày tải lên: 09/08/2014, 04:20