Molecular docking and 3d QSAR study on PfENR inhibition by triclosan derivatives

... City, Vietnam Introduction 3D QSAR models of triclosan derivatives on PfENR inhibition Docking study on PfENR Conclusions Dr Khac-Minh Thai Malaria University of Medicine and Pharmacy at Ho Chi Minh ... heterocylic containing nitrogen -NH-C(O)-R -NH-CH2-R –NH-SO2-R with R = Ar The positive effects on PfENR inhibition of triclosan derivatives from QSAR and docking results Dr Khac-Minh Thai Conclusions ... labeling and protein homology modeling pave the way for structure-based design and molecular basis of function Lead Optimisation For lead optimisation, we use conventional 2Dand 3D- QSAR methods...

A study on ambiguity caused by ellipsis and substitution in english = nghiên cứu về sự mập mờ về nghĩa gây ra do phép tỉnh lược và phép thay thế trong tiếng anh luận văn tốt nghiệp đại học

... what circumstances ellipsis and substitution usually cause ambiguity?  What are the main types of ambiguity caused by ellipsis and substitution?  How to avoid ambiguity caused by ellipsis and ... research has been done on analyzing ambiguity caused by ellipsis and substitution That is why the author wants to pay her attention and contribution to solve this problem Ellipsis and substitution ... different meanings for the sentence as a whole Such ambiguity is called 'grammatical ambiguity. ' Compare tables (1) and (2) for an example of grammatical ambiguity: (1) An example of grammatical ambiguity...

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Báo cáo khoa học: Well-deﬁned secondary structures Information-storing molecular duplexes and helical foldamers based on unnatural peptide backbones pot

... observed association constants In addition, one must consider that in heterocycle -based modules, secondary electrostatic interactions, due to the proximity of adjacent H-bond donors and acceptors, ... into a helical conformation of slightly more than one spiral turn The existence of a helical conformation was supported by endto-end NOEs and by NOEs between each amide proton and the protons on ... orientation of the amide oxygens yielded an interior cavity that is electronegative and hydrophilic Once the conformation of the amide backbone was conﬁrmed, the extension of the backbone beyond the...

Architectural inculturation and transformation case study on the three catholic churches in java

... by the author On the other hand, author decodes the meanings of the three churches based on personal experience during exploring the data and engaging in the activities in churches during the ... defines inculturation as follows: Inculturation is the intimate transformation of authentic cultural values through their integrations in Christianity, and the insertion of Christianity in the ... discussion 1.4 Limitation of the Study Based on the experience during survey for this study, there are many cases on architectural inculturation which could be found in the Catholic churches in Java...

In vivo and in vitro study on potential combination therapy of COL 3 and tamoxifen in breast cancer a pilot study

... that acute doxorubicin administration decreased COL- 3 oral bioavailability and prolonged COL- 3 elimination in rats[1 23] In the present study, a potential combination therapy of COL- 3 and tamoxifen ... combination of tamoxifen and COL- 3 is rational, based on the marked antitumor activity of both agents against a variety of solid tumors, such as breast cancer, prostate cancer, lung cancer, colon cancer, ... effects of COL- 3 and tamoxifen, in single agent or in combination against human breast cancer cell lines, MDA-MB- 231 and MCF-7 Finally, attempt would be made to account for an irregular absorption...

Standing between entertainment and politics a study on chinese anti spy fiction, 1951~1965

... hesitation and vacillation from both writers and readers on that time iv [Keywords] Anti- Spy Fiction, Popular Literature, Popular Fiction, Popular Culture, Communist China, Soviet Anti- Spy Fiction, ... production and consumption of Anti- spy fiction is a remarkable literature phenomenon that has yet to garner sufficient attention in academia Putting this phenomenon against the historical setting ... fiction in 1950s, which anti- spy fiction can be one representative of them; the popular fiction in Communist China, like anti- spy fiction, stands on the middle of entertainment and politics ambiguously...

Architectural inculturation and transformation case study on the three catholic churches in java

... think of a mosque The pointed point and the opening “tusschen” of the two upper roofs are indeed to each mosque own Indeed, the roof is also point to the ordinary pendopo-form, and the light -and ... of construction of a Catholic Church In the long term, once at beginning, they will have made with Javanese church construction, and it is to be expected, that most Javanese more taste in their ... can easily take into account the financial capacity of the parishioners, and with cash contributions, for the decoration of the connecting beams the main pillars of Javanese carving to decorate,...

A STUDY ON LANGUAGE USED BY FLIGHT ATTENDANTS

... background of language, aviation and flight attendants Giving an analysis of language used by flight attendants Pointing out some difficulties, common mistakes possibly made by Vietnamese learners and ... to see that seat belts are fastened during takeoff and landing, and assure that other Federal Aviation Administration (FAA) safety standards are followed Flight Attendants are also concerned ... HAIPHONG PRIVATE UNIVERSITY FOREIGN LANGUAGE DEPARTMENT - Graduation paper A STUDY ON LANGUAGE USED BY FLIGHT ATTENDANTS By: TRAN THI THU HUONG Class: NA1002 Supervisor: TRAN...

Báo cáo khoa học: A steady-state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor-1 in the absence and presence of vitronectin ppt

... and PAI-1 on the rate of thrombin/ PAI-1 complex formation For various combinations of kon and koﬀ for the thrombin/ TM interaction, the concentration of all reactants and intermediates was calculated ... PAI-1 The rate of thrombin inhibition by 1.5 lM PAI-1 was measured in the presence of increasing concentrations (0–800 nM) of solulin Solulin lacks the transmembrane domain and does not contain ... constructed and analyzed as described [6] The effect of increasing concentrations of solulin on the inhibition of thrombin and thrombin- VR1tPA by PAI-1 was determined To that end, a solution of...

Báo cáo hóa học: " Memory properties and charge effect study in Si nanocrystals by scanning capacitance microscopy and spectroscopy" docx

... doi:10.1186/1556-276X-6-163 Cite this article as: Lin et al.: Memory properties and charge effect study in Si nanocrystals by scanning capacitance microscopy and spectroscopy Nanoscale Research Letters ... profiling in silicon using scanning Kelvin probe microscopy J Appl Phys 1995, 77:1888 11 Huang Y, Williams CC, Slinkman J: Quantitative two-dimensional dopant profile measurement and inverse modeling ... Blanc J: Scanning capacitance microscopy Journal of Applied Physics 1985, 57(5):1437-1444 Barrett RC, Quate CF: Charge Storage in a Nitride-Oxide-Silicon Medium by Scanning Capacitance Microscopy...

Báo cáo y học: " C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages" pot

... binding to late apoptotic neutrophils, there was no detectable effect on their clearance by macrophages Ren and colleagues demonstrated that the efficiency of phagocytosis of early- and late apoptotic ... as "debris" when analysed by flow cytometry Furthermore, these cells pellet poorly in cytocentrifuge preparations, and this combined with their "invisibility" with MayGiemsa stains means that their ... unlikely that an effect of CRP on uptake of late apoptotic cells has been masked by baseline uptake of early apoptotic neutrophils in the population of aged cells that we used Conclusion By using...

Báo cáo khoa học: Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 pot

... GCAGACCATCTTGAAT -3 ), H528A forward primer (5Â-TCCCGTGTGTCAAGACGCTCTTGAAT -3 ) or H528S forward primer (5Â-TCCCGTGTGTCAAGACTCTCTTG AAT -3 ) and reverse primer (5Â-AGTCCCGGGGTGTT CATGTATGCTC -3 ) Each PCR vial contained ... Healthcare) PCR Mutations in the helicase domain of the previously used gene construct for full-length HCV NS3 [9] were introduced by PCR using Q526A forward primer (5Â-TCCCGTGTGT GCAGACCATCTTGAAT -3 ), ... 0 .30 0 .37 0.04 0.84 0.58 value compared with the helicase variants at a 95% condence level Inhibition of NS3 protease variants The effect of changes in the helicase residues on the inhibition...

A PROSPECTIVE STUDY ON DETECTION, SUBTYPE ANALYSIS, CHARACTERIZATION, MOLECULAR EPIDEMIOLOGY AND TRANSMISSION OF INFLUENZA VIRUSES AMONG UNIVERSITY STUDENTS AND STAFF IN SINGAPORE

... Understand the molecular epidemiology and phylogeography of influenza in localized university community by integrating molecular data and epidemiological data to gain insights into the transmission ... Stalk region antagonize interferon (Munier et al 2010; Sorrell et al 2010) 1.4 Epidemiology of Influenza 1.4.1 Seasonal influenza Seasonal influenza viruses cause infections in humans every year ... Neighbor-Joining tree of Hemagglutinin (HA) of pH1N1/09 strains (in red are on- campus and in green are off-campus strains) detected in 2009 (July & August) on a Singapore university campus and community...

STUDY ON MECHANICAL AND THERMODYNAMIC PROPERTY OF MOLECULAR CRYOCRYSTALS CO2 AND n2o UNDER PRESSURE

... dependence of zone center libron frequencies and the pressure dependence of the three vibron modes of vibration in solid CO2 at pressures ≤ p ≤ 16 GPa and temperatures ≤ T ≤ 300 K[12] Properties of solid ... and pressure We only have the experimental data for the phase diagram and the molar volume of α -CO2 and α-N2 O under pressure The dependence of thermodynamic quantities on temperature for α -CO2 ... MECHANICAL AND THERMODYNAMIC PROPERTY FOR α -CO2 AND α-N2 O CRYOCRYSTALS AT PRESSURE p = It is known that the interaction potential between two atoms in α phase of molecular cryocrystals of N2 type...

A study on the opportunities for and constraints on developing students’ oral skills at an upper-secondary school

... that they are good at writing and reading since they like and usually practice these skills; in contrary, they are bad at listening and speaking as their vocabulary is not enough and their pronunciation ... follows: -A study on the strategies for improving students’ oral skill at an Upper-Secondary School in Nghean 41 -A study on the combination of teaching speaking skill and grammar for developing students’ ... ideas in vocabulary and syntactic structures of the target language According to Kathleen M Bailey and Lance Savage (1993: 18), depending on the formality and importance of the speech situations...

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