functional characterisation of phosphodiesterase 4d7 in prostate cancer

... hepatic cancer, colon cancer and lung cancer. Immunostaining of prostate cancer tissue with antibodies against AMACR and PSAFigure 2 Immunostaining of prostate cancer tissue with antibodies against ... mRNA in prostate cancer line LNCaP, but only very weak expression of AMACR mRNA was observed in normal adult liver and pancreas (Figure 1A) . In contrast, t...

Ngày tải lên: 18/06/2014, 15:20

... al.: Inhibition of xenotropic murine leukemia virusrelatedvirus by APOBEC3 proteins in PBMCS. J Virol 2011, 85:4888–4897. 18. Rodriguez JJ, Goff SP: Xenotropic murine leukemia virus -related virus ... soon. Downregulation of APOBEC3G by Xenotropic Murine Leukemia -Virus Related Virus (XMRV) in Prostate Cancer Cells Virology Journal 2011, 8:5...

Ngày tải lên: 18/06/2014, 18:20

... is linked to the invasivenes s of prostate cancer ce lls [12] and participates in the regulation of the interactions between prostate cancer cells and endothelial cells, the later involving the Rock ... migration of cancer cells. The most int riguing finding of the present study was that the function of MDA-7 in prostate cancer cells appears to be dependent...

Ngày tải lên: 18/06/2014, 19:20

... is linked to the invasivenes s of prostate cancer ce lls [12] and participates in the regulation of the interactions between prostate cancer cells and endothelial cells, the later involving the Rock ... context of a limited number of cytokines that inhibit the adhesiveness, growth and migration of cancer cells. The most int riguing finding of the present stud...

Ngày tải lên: 20/06/2014, 03:20

... arthritis (JIA) and to investigate the functional and anatomical heterogeneity of these cell subsets in relation to the expression of the inflammatory chemokine receptors CXCR3 and CCR5. Memory ... provided the original work is properly cited. Abstract The aim of the study was to characterise CCR7 + and CCR7 - memory T cells infiltrating the infla...

Ngày tải lên: 09/08/2014, 06:22

... Radiother Oncol 2008, 88(1):4 6-5 2. doi:10.1186/174 8-7 17X- 5-2 3 Cite this article as: Niyazi et al.: Choline PET based dose- painting in prostate cancer - Modelling of dose effects. Radiation Oncology ... con- cerning the primary detection and the staging of pros- tate cancer [27]. In principle, signal-genera tion is based on an incre ased choline meta...

Ngày tải lên: 09/08/2014, 08:22

... 5:108 http://www.ro-journal.com/content/5/1/108 Page 9 of 12 RESEA R C H Open Access The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation Justine Rudner 1 , ... this article as: Rudner et al.: The Akt-inhibitor Erufosine induces apoptotic cell death i...

Ngày tải lên: 09/08/2014, 09:20

... human prostate carcinoma xenografts receiving combinations of androgen-deprivation therapy and/ or radiotherapy. Pre-radiation and on days 1 and 9 following radiation three repeated DWMRI and ... 6:65 http://www.ro-journal.com/content/6/1/65 Page 6 of 9 RESEARC H Open Access Early prediction of response to radiotherapy and androgen-deprivation therapy in...

Ngày tải lên: 09/08/2014, 09:20

... Access The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques Jana Vranova 1,4 , Stepan Vinakurau 2 , ... article as: Vranova et al.: The evolution of rectal and urinary toxicity and immune response in prostate cancer patient...

Ngày tải lên: 09/08/2014, 09:20

... FCS-containing media during genistein incubation and the incubation with higher genistein doses. Mechanisms of interaction To search for mechanisms of interaction we investigated protein expression of ... purposes) Radiation Oncology Open Access Research In vitro studies on the modification of low-dose hyper-radiosensitivity in prostate cancer cell...

Ngày tải lên: 09/08/2014, 09:22

... 1 of 9 (page number not for citation purposes) Radiation Oncology Open Access Research Potentials of on- line repositioning based on implanted fiducial markers and electronic portal imaging in ... Jaf- fray DA, Catton CN: On- line aSi portal imaging of implanted fiducial markers for the reduction of interfraction error dur- ing conformal radioth...

Ngày tải lên: 09/08/2014, 09:22

... 29:162 http://www.jeccr.com/content/29/1/162 Page 8 of 8 RESEA R C H Open Access XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells Zhaoquan Xing 1† , Zunlin Zhou 2† , Rong Yu 3,4 , ... occur during the development of prostate cancer. It is interesting to evaluate the potential regulatory effects of somatostatin on...

Ngày tải lên: 10/08/2014, 10:20

... efficacy findings of the trial (Table 1) prompt ed the Independent Data Monitoring Committee to recom- mend unblinding the trial at the time of the interim analy- sis and the crossover of patients ... growth to prostate cancer cells. Interestingly, however, in mo del systems they may be inhibited by antiandrogens targeted to the ligand-binding domain, such as MDV3100 (...

Ngày tải lên: 10/08/2014, 21:23

... Prostate Cancer 94 1.9.5 Prostate Cancer Diagnosis and Treatment 97 1.10 cAMP Signalling in the Prostate and Prostate Cancer 105 1.10.1 cAMP PDEs in Prostate Cancer 105 1.10.2 Protein Kinase ... Phosphodiesterase 4D7 is downregulated as prostate cancer becomes androgen-insensitive 144 3.2.2 Validation of PDE4D7 protein expression in AS and AI PC cell li...

Ngày tải lên: 22/12/2014, 21:15