Fatty Liver Disease : Nash and Related Disorders - part 6 docx

... should be aimed at arresting disease progression, and is therefore restricted to thosepatients with NASH and more advanced ﬁbrosis. Fatty Liver Disease: NASH and Related Disorders Edited by Geoffrey ... 2000; 3 3: 7 16 24.32 Schaffner F, Thaler H. Non-alcoholic fatty liver dis-ease. In: Popper H, Shaffner F, eds. Progress in Liver Diseases, Vol. 8. New York: Grune & Stratton, 198 6: 283–98.33 ... iron, and ﬁbrosis: ethnic-speciﬁc association of NASH with C282Y but not with ﬁbrotic severity. Hepato-logy 2002; 3 6: 142–9.8 Clarke JM, Brancati FL, Diehl AM. Non-alcoholic fatty liver disease. ...

Fatty Liver Disease : Nash and Related Disorders - part 1 ppt

... Gastroenterology 1999; 11 6: 1413–9. 16 Angulo P. Non-alcoholic fatty liver disease. N Engl J Med2002; 1 6: 1221–31.17 Younossi ZM, Diehl AM, Ong JP. Non-alcoholic fatty liver disease: an agenda for clinical ... Non-alcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999; 11 6: 1413–9.14 Mulhall BP, Ong JP, Younossi Z. Non-alcoholic fatty liver disease: ... 199 9: 9 4: 2 462 –74.5 Brunt EM. Non-alcoholic steatohepatitis: deﬁnition and pathology. Semin Liver Dis 2001; 2 1: 3 – 16. 6 Burt AD, Mutton A, Day CP. Diagnosis and interpreta-tion of steatosis and...

Fatty Liver Disease : Nash and Related Disorders - part 3 potx

... 1989; 24 8: 169 –74. 63 Barnes PJ, Karin M. Nuclear factor-κB: a pivotal tran-scription factor in chronic inﬂammatory diseases. N EnglJ Med 1997; 33 6: 1 066 –71. 64 Crespo J, Cayon A, Fernandez-Gil ... Tumornecrosis factor-α promoter polymorphisms and insulinresistance in non-alcoholic fatty liver disease. Gastro-enterology 2002; 12 2: 274 –80. 66 Walston J, Seibert M, Yen C, Cheskin LJ, Andersen RE.Tumor ... non-diabeticprecirrhotic individuals with fatty liver as well as NASH [13].Role of oxidative stress and the ‘two-hit’ hypothesisBecause both fatty liver and NASH are associated withIR and...

Fatty Liver Disease : Nash and Related Disorders - part 4 pot

... in structure and function of the genes of fatty acidmetabolism and transport to the pathogenesis and the evolution of fatty liver diseases. Fatty Liver Disease: NASH and Related Disorders Edited ... cirrhosis. Liver Transpl2001; 7: 363 –73.89 Ockner RK, Kaikaus RM and Bass NM. Fatty acidmetabolism and the pathogenesis of hepatocellular car-cinoma: an hypothesis. Hepatology 1993; 1 8: 66 9– 76. 90 ... Peroxisomal and mitochondrial fatty acid β-oxidation in mice nullizygousfor both peroxisome proliferator-activated receptor α and peroxisomal fatty acyl-CoA oxidase: genotype corre-lation with fatty liver...

Fatty Liver Disease : Nash and Related Disorders - part 5 pdf

... with fatty livers:implications for non-alcoholic fatty liver disease patho-physiology. Hepatology 2001; 3 4: 69 4–7 06. 68 Torbenson M, Yang SQ, Liu HZ et al. STAT-3 over-expression and p21 up-regulation ... Inthese mice, hepatic TNF and IL -6 mRNA expressionwas altered after partial hepatectomy [67 ], and produc-tion of TNF and IL -6 was defective after acute CCl4toxicity [69 ]. Leptin repletion in ... impairedregeneration of fatty livers. Am J Pathol 2002; 16 1: 155 61 . 69 Leclercq IA, Field J, Farrell GC. Leptin-speciﬁc mechan-isms for impaired liver regeneration in ob/ob mice aftertoxic liver injury: roles...

Fatty Liver Disease : Nash and Related Disorders - part 7 ppsx

... steatosis: innocent bystanderor guilty party. Hepatology 1998; 2 7: 1 463 6. 62 Free radicals, and other reactive species and disease. In: Halliwell B, Gutteridge JMC, eds. Free Radicals inBiology and ... phlebotomy on non-alcoholic steatohepatitis (NASH) [Abstract]. Gastroenterology 2000; 118 (Part 2,Suppl. 2 ): 66 79.218AbstractNon-alcoholic fatty liver disease (NAFLD), as con-ventionally recognized, ... Non-alcoholic fatty liver disease: an agenda for clinical research. Hepatology2002; 3 5: 7 46 52.4 Hasan I, Gani RA, Machmud R et al. Prevalence and risk factors for non-alcoholic fatty liver...

Fatty Liver Disease : Nash and Related Disorders - part 8 potx

... Younossi ZM. Non-alcoholic fatty liver disease: an overview. J Gastroenterol Hepatol2002; 1 7: 11 36 43.3 Matteoni CA, Younossi ZM, Gramlich T et al. Non-alcoholic fatty liver disease: a spectrum ... malnutrition and gut-derived endotoxins and other bacterialtoxins contribute to the genesis of post-bypass liver disease. Fatty Liver Disease: NASH and Related Disorders Edited by Geoffrey C. Farrell, ... Protein-calorie mal-nutrition and the liver. Prog Liver Dis 1972; 4: 527– 36. 42 Sims EA, Horton ES. Endocrine and metabolic adapta-tion to obesity and starvation. Am J Clin Nutr 1 968 ; 2 1: 1455–70.43...

Fatty Liver Disease : Nash and Related Disorders - part 10 pdf

... prevention 1 16 NASH management 202c-myb, hepatic stellate cell activation 145coeliac disease 250, 2 56 cohort studiesin diabetes 267 , 267 – 268 in NASH 264 , 265 , 266 in obesity 268 , 268 – 269 , 269 –270collagenﬁbrosis ... drugsinterleukin-1β (IL-1β), ﬁbrosis 1 46 interleukin-4 (IL-4), TNF-α effects 128interleukin -6 (IL -6 ) 291interleukin-10 (IL-10), mutations 73interleukin-15 (IL-15), ob/ob mouse model 128interleukin- 16 (IL- 16) , ... Transpl 2004; 10 (Suppl. 1 ): 69 –73.52 Dam-Larsen S, Frank Mann M, Andersen IB et al. Long-term prognosis of fatty liver: risk of chronic liver disease and death. Gut 2004; 5 3: 750–5.53 Harrison...

Fatty Liver Disease: NASH and Related Disorders ppt

... steatosis and steatohepatitis III:peroxisomal β-oxidation, PPARα, and steatohepatitis. AmJ Physiol Gastrointest Liver Physiol 2001; 28 1: G1333–9. Fatty Liver Disease: NASH and Related Disorders Edited ... insulin resistance, famil-ial tendency, and severity of disease. Am J Gastroenterol2001; 9 6: 2957 61 .1 06 Knobler H, Schattner A, Zhornick T et al. Fatty liver: an additional and treatable feature ... condition. Nutri-tion 2001; 1 7: 953– 966 .119 Day CP, James OF. Hepatic steatosis: innocent bystanderor guilty party? Hepatology 1998; 2 7: 1 463 6. 120 Day CP, James OFW. Steatohepatitis: a tale of...

PARKINSON’S DISEASE AND RELATED DISORDERS - PART 6 ppt

... striato-nigral degeneration showing sym-metrical atrophy and discolorationof the putamen Figure 3211C-raclopride binding in a normal subject (left) compared with that in Parkinson's disease (middle) ... atrophy©2004 CRC Press LLCFigure 42 T2-weighted MRI (upper) shows hyperintensity of the middle cere-bellar peduncles and the cerebellum. The axial proton-density MRI (lower) showshyperintensity ... E)©2004 CRC Press LLCFigure 36 Axial (upper) and coronal(lower) T2-weighted MRIs showingputaminal hypointensity (arrowed)in a patient with striatonigral degen-eration©2004 CRC Press LLCFigure...

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