Cyclic stretch enhances the expression of Toll-like Receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-B pathway doc
Cyclic stretch enhances the expression of Toll-like Receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-B pathway doc
... fre- quency of 1 Hz (60 cycles per min) for various periods of time. To determin e the roles of c-Jun N-terminal kinase (JNK), p38 MAP kinase or p42/p 44 MAP kinase in the expression of stretch- induced ... Access Cyclic stretch enhances the expression of Toll-like Receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase an...
Ngày tải lên: 10/08/2014, 05:21
Tài liệu Báo cáo khoa học: ¨ Induction of Kruppel-like factor 4 by high-density lipoproteins promotes the expression of scavenger receptor class B type I pptx
... adhesion to the endothelial surface and prolongation of clotting time following the induc- tion of KLF4 under in ammatory states, and implicat- ing KLF4 as a regulator of endothelial activation in response ... the promoter of SR-BI contained multiple putative KLF4 binding sites. However, the direct effect of KLF4 on the expression of SR-BI remains unknown. Here,...
Ngày tải lên: 18/02/2014, 04:20
báo cáo hóa học: " The effect of consequent exposure of stress and dermal application of low doses of chlorpyrifos on the expression of glial fibrillary acidic protein in the hippocampus of adult mice" pptx
... and in combination, showed increased GFAP expression in offspring in the CA1 sub-field of the hippo- campus, and white matter and granular cell layer of the cerebellum [17,18]. In the present ... exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebell...
Ngày tải lên: 20/06/2014, 00:20
báo cáo hóa học:" Constitutive expression of Atlantic salmon Mx1 protein in CHSE-214 cells confers resistance to Infectious Salmon Anaemia virus" docx
... amplicon- specific melting peaks were observed in these samples. The absence of the 220 bp band on agarose gel in these samples (Fig. 3O, R, U) further confirmed the validity of melting curve analyses of these ... protein accumu- lates in the nucleus and interferes with primary transcrip- tion of influenza virus in the nucleus, whereas the human MxA protein which...
Ngày tải lên: 20/06/2014, 04:20
báo cáo khoa học: " Multiple evidence for the role of an Ovate-like gene in determining fruit shape in pepper" pptx
... between the sequences are localized in position 41 9, which is inside the first exon of the gene while the other two, in positions 6 54 and 746 , are located inside the one and only intron of the gene. ... CaGA20ox1 expression in the two fruits: there is an increase in the expression of the gene in the 5 DAA fruit of the infiltrated plant...
Ngày tải lên: 11/08/2014, 11:21
Tài liệu Báo cáo khoa học: Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics docx
... activators of the p38 and PtdIns 3 -kinase pathways including thr ombin, dexamethasone, angiotensin II and prostaglandins stimulate the expression of CTGF/CCN2 efficiently [8 ,43 45 ]. The role of the cytoskeleton ... anisomycin- and serum-induced CTGF/ CCN2 gene expression indicating that inducible CTGF/ CCN2 gene expression is independent of the Ras signa...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: Thyroid hormone induces the expression of 4-1BB and activation of caspases in a thyroid hormone receptor-dependent manner pptx
... luciferase, even in the presence of the 4- 1BB-Ligand, it increased the caspase activities. An increase in the caspase activities was also observed in the HeLaTR cells transfected with 4- 1BB cDNA, and the 4- 1BB-Ligand ... 4- 1BB-Ligand further increased the caspase activities of the HeLaTR cells overexpressing the 4- 1BB. Furthermore, up-regulation of 4...
Ngày tải lên: 23/03/2014, 18:20
Báo cáo khoa học: PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AM pptx
... allele be insufficient in maintaining its own expression in the intestinal nonendocrine cells, and in preventing the formation of intestinal polyps for the nonendocrine intestinal epithelia? We ... Cis-Acting elements and tran- scription factors involved in the intestinal specific expression of the rat calbindin-D9K gene: binding of the intestine-specific trans...
Ngày tải lên: 30/03/2014, 16:20
Báo cáo sinh học: "Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer" doc
... c regulation of the IL-13Ra2 gene in pancreatic cancer cell lines and investigated whether the IL-13Ra2 gene can be modulated by epigenetic mechanisms. We have also examined the effect of HDAC inhibitors ... novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Histone modification enhances the effectiveness of IL-13 receptor targeted immunotoxin in murine models of human pancreatic cancer" pot
... c regulation of the IL-13Ra2 gene in pancreatic cancer cell lines and investigated whether the IL-13Ra2 gene can be modulated by epigenetic mechanisms. We have also examined the effect of HDAC inhibitors ... novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and...
Ngày tải lên: 20/06/2014, 03:20