Báo cáo y học: "Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats" potx

... the interleukin 5 gene; λ Ig: the λ -chain of immunoglobulin gene; γIg: the γ-chain of immunoglobulin gene; IFN-ind: the interferon-inducible gene 6-16; IL4R: the interleukin 4 receptor gene; ... dehydrogenase subunit 4 gene, IL5 – the interleukin 5 gene, λ Ig – the λ -chain of immunoglobulin gene, γIg – the γ-chain of immunoglobulin gene, IFN-ind – the interferone-inducible...

Ngày tải lên: 02/11/2012, 11:08

... analyzed individually. Flow cytometry analysis The cell type composition and level of protein expression for some genes in the inguinal lymph nodes were analyzed by flow cytometry. Single cell ... cells in lymph nodes in DA and E3 naïve rats and rats 8 days after pristane injection Total cell number (millions) Difference between Difference between Cell type DA day 0* E3 day 0...

Ngày tải lên: 09/08/2014, 01:23

... previously reported data showing an age-related increase in OCN gene expression in OA and a decrease in controls [16]. This finding is supportive of an increase or main- tenance of bone volume in OA individuals ... subsequently accumulated in the mineralised matrix. Increased OPN may augment OB synthetic activity by increasing OB longevity and surface extent of bone formation. H...

Ngày tải lên: 09/08/2014, 08:23

... microarray analysis. Several of the differentially expressed genes encoded key enzymes of intermediary meta- bolism, including those involved in glycolysis and gluconeogenesis, fatty acid degradation, ... enzymes of serine ⁄ glycine metabolism: Glycine decarb- oxylase, a component of the glycine dehydrogenase complex that converts glycine to serine, is predomin- antly expressed in peripor...

Ngày tải lên: 23/03/2014, 10:20

... Wild-type plant. (E) Structures of three major anthocyanins accumulated in Arabid- opsis [1]. Glu, glucose; Xyl, xylose; p-Cou, p-coumaroyl; Sin, sinapoyl; Mal, malonyl. Anthocyanin biosynthetic genes ... reported previously [7], indicating the involvement of PfGST1 in anthocyanin accumulation in perilla plants. A GST-like protein, presumably involved in anthocyanin accumulation in...

Ngày tải lên: 23/03/2014, 07:20

... bind- ing. Interestingly, five actin-binding genes appeared in the list; namely: anillin (ANLN, ID: R16712 ), destrin (DSTN, ID: AA424824 ), utrophin (UTRN, ID: AA676840), cyclin- dependent kinase ... greatly expand the understanding of SHIV-host interaction beyond the limited number of cell types or cytokines generally exam- ined. In animals free of clinical signs of SHIV, altered baseli...

Ngày tải lên: 20/06/2014, 01:20

... 15 aldo/keto-reductase. Additionally, five operons with unknown function were induced including ydaDEGPS, yfhFLMP, yfkDJM, yjgBCD, and yxiBCS At 83 µA/cm 2 several genes for ameliorating oxidative stresses ... shown. Gene Name Expression Ratio Gene Function/product hisB 2.1 imidazoleglycerol-phosphate dehydratase hisD 2.1 histidinol dehydrogenase hisH 2.1 imidazole glycerol pho...

Ngày tải lên: 20/06/2014, 23:20

... suffering from rheumatoid arthritis (RA) or osteoarthritis (OA) were analyzed using Affymetrix HuGeneFL microarrays. Data assessment was done using Affymetrix Microarray Suite 5.0. CXCL, Cys–X–Cys ... and CXC chemokines, with a single amino acid separating the first two cysteines. Cys–X–Cys ligand (CXCL)9 and CXCL10 are members of the small cytokine (intercrine/chemokine) CXC subfamily and...

Ngày tải lên: 09/08/2014, 01:23

... and microcytotoxicity assays. Preliminary association analysis was conducted by χ 2 test- ing on contingency tables comparing the three genotypic frequencies between cases and control individuals to yield a ... developing JRA. We examined the TPSN gene, which encodes tapasin, an endoplasmic reticulum chaperone that is involved in antigen processing, to elucidate its involvement, if any,...

Ngày tải lên: 09/08/2014, 06:22

... incu- bated with Tris-buffered saline containing isotype-matched antibodies instead of the primary antibody; they were invar- iably negative (data not shown). The intensity of antibody staining ... a type-1 cytokine profile [4,5]. The cellular infiltrate is defined largely by the composition of locally produced chemokines as well as by the diversity of circulating leuko- cytes expressing ......

Ngày tải lên: 09/08/2014, 06:22