THE MOLECULAR BASIS OF PLANT GENETIC DIVERSITY pdf
Báo cáo khoa học: The molecular basis of heme oxygenase deficiency in the pcd1 mutant of pea pot
... characterized the contribution of these assay components by omitting them individually. In the absence of ferredoxin the reaction rate decreased to 46.5% of the complete reaction while the absence of ascorbate ... account for the failure of the PsHO1 probe to detect any HO2-like sequences in Southern blot experiments. Whatever the basis of the recovery of phy...
Ngày tải lên: 30/03/2014, 11:20
Molecular Basis of Pulmonary Disease Insights from Rare Lung Disorders pdf
... maintaining the same degree of efficacy with the f ewest number of subjects exposed to the more toxic therapy. There are a number of alternative study designs that can be considered in the context of rare ... measure the actual difference between treatment outcomes. There are many approaches to the design of a trial and many of them can achieve cer- tain economies in te...
Ngày tải lên: 05/03/2014, 23:20
Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx
... confirmed by the kinetic analysis of a purified GPI-anchorless soluble version of the mutant protein. The K cat ⁄ K m value of the mutant TNSALP was less than one-tenth of the K cat ⁄ K m value of the ... TNSALP (R433C). The rate of the intracellular transport of the mutant protein was similar to that of the wild-type protein, as assessed by the acquisition...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Transthyretin and familial amyloidotic polyneuropathy Recent progress in understanding the molecular mechanism of neurodegeneration pdf
... showing the location of amyloidogenic mutations and position of b-strands. (A) The struc- ture of the polypeptide backbone of the two chains (purple and blue) is shown along with the location of the ... within a tissue and that the distribu- tion of TTR deposition reflects the presence of these endogenous factors. In the case of the Ab protein of Alzheimer...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc
... USA) and sequenced to verify the presence of the mutation and the absence of any other substitution intro- duced during the PCR. Mutated genes were further cloned in the pET28 expression vector ... saturating concentration of the co-substrate. When determining the K m3-phosphoglycerate of the wild-type and mutant enzymes, the concentration of GTP present in the a...
Ngày tải lên: 16/03/2014, 01:20
Báo cáo khoa học: The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties ) comparative modeling to probe the molecular basis pdf
... lactate, the activity of LDHB was 86% of the value determined in the absence of lactate, and at 300 mm lactate, the activity of LDHB was only 24% of the same control value. Characterization of glucose ... Examination of the model of the R state of LDH shows a much higher density of posi- tive charge in the region of contact between the mono- mers than i...
Ngày tải lên: 16/03/2014, 05:20
Báo cáo Y học: A polymer with a backbone of 3-deoxy-D-glycero -D-galacto -non-2ulopyranosonic acid, a teichuronic acid, and a b-glucosylated ribitol teichoic acid in the cell wall of plant pathogenic Streptomyces sp. VKM Ac-2124 pdf
... proves the position of the acetamido groups at C-2 and C-3 of this sugar. The signal of the H-5 of this sugar appeared as a doublet, which suggests the absence of protons at H-6. In addition, the ... were observed in the region of resonances of the CH 3 CO– groups. The presence of 3-deoxynonulosonic acid with the b-configuration of the glycosidic bond fo...
Ngày tải lên: 17/03/2014, 10:20
EVOLUTION OF THE MOLECULAR BIOLOGY OF BRAIN TUMORS AND THE THERAPEUTIC IMPLICATIONS pdf
... mortality of the patient. Moreover, the presence of the blood-brain barrier (BBB) limits the passage of a wide variety of anticancer agents. The high incidence of recur‐ rence and poor prognosis of ... that genetic instability of high grade gliomas provides the way of angiogenesis independently of hypoxia (such as chronic HIF Evolution of the Molecular Bi...
Ngày tải lên: 23/03/2014, 10:20
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