... understanding oftheC4 pathway, the identification ofthe evolutionary changes within the genome during the evolution oftheC4pathway With these discoveries, scientists now have some ofthe key ... expansion of knowledge ofC4 photosynthesis following the first publication oftheC4pathway in 1967 stands out as one ofthe most exciting eras in the plant sciences As theC4 photosynthesis was ... together by linking C4 biochemistry, C4 anatomy, and the biogeography ofC4 plants It is the efforts of these and the many other researchers who made the telling oftheC4 story possible Their history...
... or JPY), Tennessee (TN), or the Netherlands (NL) and 16 AMPV F sequences The first two digits ofthe HMPV sequence names indicate the year ofthe isolate The names ofthe AMPV sequences indicate ... site A ofthe related RSV F protein [36] (Figure 1) Some ofthe variations in this region, such as E294G, were present in viruses of both the A1 and A2 subgroups Viruses ofthe A2 lineage had the ... strains of HMPV and assigned to one ofthe four proposed lineages (A1, A2, B1, or B2) based on phylogenetic analysis, discussed further below [32] Ofthe 68 strains sequenced, 34 (50%) were of the...
... synthesis Phosphatase Conserved hypothetical Hypothetical Figure of PBS rod gene regions ofthe different pigment types of marine Synechococcus Comparison Comparison of PBS rod gene regions ofthe ... adapters Altogether, these data suggest that the different components ofthe PBS have evolved almost independently from each other in the marine Synechococcus group Indeed, the core ofthe PBS has ... photosensors of unknown function [40] In the following sections, we have analyzed more specifically the phyletic profile (that is, the different patterns of occurrence of orthologs in the set of Synechococcus...
... Therefore, in this report we analysed MDR taxonomy on thebasisofthe entire set of currently known MDR members, and completed the work initiated by Nordling et al with identification of further ... superfamily, and their relationships to several protein classification efforts Furthermore, recruitment of selected members of this superfamily may offer clues about the evolution of some metabolic pathways, ... mark the boundaries of protein macrofamilies COGs are also indicated in boxes The complete names ofthe protein subfamilies are indicated in Tables 3–8, according to the protein family to which they...
... decreases along the Ngen generations The probability of occurrence of a crossover, Pc, and the method of selection, on the other hand, determine the selection pressure ofthe genetic algorithm The selection ... parameters The size ofthe population (i.e., number of individuals), Nind, and the probability of occurrence of a mutation, Pm, are two such parameters associated with the diversity ofthe population The ... value ofthe objective function, OF0 The point obtained at the end ofthe procedure, Xf = (x1,f, x2,f,…, xn,f), contains the final values ofthe decision variables, and is associated with the final...
... comparing the integrals ofthe empirical CDFs ofthe control and treatment group earnings distributions for various values of o Table displays the re- sults of tests ofthe null hypothesis of equality ... of self selection These narrow the range of dependence across outcome states (4) The range ofthe estimated proportion of people benefitting from the program in the sense of gross outcomes (the ... evaluation ofthe experience ofthe program (its process) or an evaluation ofthe benefits ofthe program? The evidence presented here suggests that respondents report a net benefit inclusive of their...
... functionality and phylogeny However, the nature ofthe connections between these factors needs to be understood at the level ofthe protein domain The global properties ofthe HTFN topology are partially ... [47] and other related factors such as rox [48], mxi [47], miz-1 [49] TRRAP, GNC5, bin-1 [50] Group F contains 90% ofthe members ofthe nuclear receptor hormone superfamily ofthe HTFN (they also ... contains the 90% ofthe members of nuclear receptor superfamily (they are Zn fingers also) ofthe HTFN G 19 31% MAD domains SMAD family proteins and b-catenin and APC related factors from the acquisition...
... classes ofthe CDRs for the Fab4E11 fragment ofthe wild type and analyzed the potential effects of some mutations on the corresponding structures According to the predictions, the structures of L-CDR2 ... provide the major part ofthe free energy of interaction with the antigen [20,21] Paratope of an mAb neutralizing the dengue virus We have undertaken a detailed analysis ofthe relations between the ... particular, the specificity of recognition towards this virus to the exclusion of other flaviviruses, the cross-reactivities towards the four viral serotypes, and the mechanisms of neutralization at a molecular...
... ratio ˜ Uw ofthe actual number of users of word w (Uw ) over ˜ the expected number of users of w (Uw ), and DT = Tw ˜ is calculated analogously fo the actual/expected Tw ˜ ˜ number of threads ... annotate a large portion ofthe MZEE corpus, the training data consisted ofthe disjoint subsets ofthe English and German CELEX wordlists (Baayen et al., 1995), as well as the words used in Covo ... frequency for the 851 most common anglicisms in MZEE Finally, from the comparison of timespans in Table 3, we see that the predictive ability (R2 ) ofthe three measures increases as the timespan...
... number ofmolecular studies using other markers [40,51–54] However, conflicting molecular evidence on the exact position ofthe Myriapoda exists, either supporting a common branch with the Pancrustacea ... [41,44], although the support values in the present are significantly higher This observation supports the notion ofthe usefulness of hemocyanin sequences for the resolution ofthe arthropod phylogenetic ... PAGE (Figs and 2; Table 1) The N-terminal amino acid sequences (see above) allow the assignment ofthe HcA clone to the major sequence ofthe upper hemocyanin band in the SDS/PAGE gel (Fig 1) Two...
... inhibitors and others [56] The targeting features ofthe propeptide of barley lectin have been analyzed by amino acid substitutions [57] The unique extension of AtP14 might indicate the presence of a short ... (penultimate lane) Expression of mRNA encoding ef-1a was used as a control ofthe quality ofthe RNA preparation, ofthe reverse transcription reaction and for expression reference There is no simple correlation ... example of a nonglycosylated triplet at position Asn70 [48] The majority ofthe peroxidases carry one or two putative glycans Seven appear to be nonglycosylated Therefore, the high number of glycans...
... each other The biochemical details of binding and recognition set the rules of engagement that shape the pacing, scale, and pattern of diversity and the nature of evolutionary change Ofthe many ... surfaces of host cells Parasite escape from T cell recognition can occur at any ofthe processing steps, including the digestion of proteins, the transport of peptides, the binding of peptides by the ... CD66e found on the squamous epithelium ofthe uterine portio Other Opa variants bind more effectively to CD66a found on the epithelium ofthe cervix, uterus, and colon tissues Thus, the CD66-specific...
... genes On the other hand, the lack of growth ofthe wildtype strain on D-allitol and L-iditol may either be due to a lack of uptake of these hexitols, or due to a lack of lad1 expression by these ... Enzymatic conversion of hexitols and ketohexoses by Lad1 The identification of L-xylo-3-hexulose as the product ofthe oxidation of galactitol by Lad1 raised the question of whether other hexitols would ... among the members ofthe Lad1 terminal clade but which are functionally different from those present in other SDHs, are located at the facing rims ofthe two domains ofthe protein that form the...
... are the main positives and negatives of diversity? Katherine Phillips: The main benefit of diversity is often assumed to be the impact ofthe different perspectives brought to the table by the ... corporates in the late 1990s, the Sarbanes-Oxley Act of 2002 in the USA and the Higgs Review of Corporate Governance in 2003 in the UK called for significant changes to the composition of corporate ... the board to offset the relative lack of independent advice and to reduce the homogeneity ofthe directors There is unusually strong consensus within academic research that a greater number of...
... organism is thus faced with the more complex choice of finding the value ofthe trait that maximizes fitness in the face of trade-offs with other traits of importance In the above example, evolution ... of scientists While the detail can exist without the synthesis, the synthesis gives the detail added value While some ofthe detail may change, be lost, or added to, the synthesis I hope will ... with the interaction of organisms with their environment The organisms can be considered at various levels of a hierarchy, comprising the individual, the population (groups of individuals of the...
... that are inevitable, given the degree of complexity of these improvements and the scale ofthe network where they are deployed After all, aspects that include the size ofthe network, finite link ... these and other questions have motivated the development of a theory ofthe Internet that is firmly based on some ofthe general principles reported in this paper and derived from a study ofthe ... contrast to these first two categories, which only alter the actions ofthe end hosts (by making the proposed changes to the TCP protocol) but not that ofthe routers, the third type of TCP improvements...
... with the emergence ofthe Chordata On the other hand, p67phox seems to be absent in the ascidian Ci intestinalis ofthe Urochordata, a sister group ofthe Vertebrata, suggesting loss ofthe p67phox ... oxygens ofthe 3-phosphate; NH1 and NH2 of Arg105 form hydrogen bonds with the 4-OH and 5-OH ofthe inositol moiety; and the aromatic ring of Tyr59 stacks against one face ofthe inositol ring (the ... including the Opisthokonta, the Amoebozoa, the Plantae, the Excavata, the Rhizaria, and the Chromalveolata (the Heterokonta plus the Alveolata): animals and fungi belong to the Opisthokonta; the social...
... representation ofthe domain structure ofthe various PFK-2 ⁄ FBPase-2 isoenzymes of T brucei The domain structure ofthe enzymes was inferred from the amino acid sequences predicted from the ORFs ... PFK27 in the cluster Furthermore, the phylogenetic analysis also showed that the formation ofthe four isoenzymes in the trypanosomatids has occurred already in the common ancestor ofthe genera ... enzyme [24], is within the PFK-2 domain, but the residue is not part ofthe active site The other four positions lie in the N-terminal extension The Tb4 amino acid sequences of stocks TREU927 ⁄...
... court ofthe emperor The child watches the bird The bird weeps for the child The child begs the bird to listen .The bird dresses up the child The child grows up The child watches the bird The bird ... emperor The emperor feels that the brothers tempt a beauty into the game The kingdom saves the life from crumbling the earth into the bird The kingdom forces the whip into wiping the tears on the ... Random The emperor rules the kingdom The kingdom holds on to the emperor The emperor rides out ofthe kingdom The kingdom speaks out against the emperor The emperor lies The emperor rules the kingdom...
... amongst other things, the continuous creation of matter to keep the density ofthe expanding Universe constant The steady-state universe was abandoned in the 1960s because ofthe properties ofthe ... provide an estimate of H0 , together with a strong confirmation ofthe validity ofthe Hubble law and, therefore, ofthe Cosmological Principle Another test of this principle is the so-called Hubble ... be the case in the early years ofthe 20th century when the first steps were taken, by Einstein and others, towards a scientific theory ofthe Universe Little was then known empirically about the...