I. Benh di truyen phan tir
2. Hoi chiirng lien quan den dot bien NST
Hogt dpng cda GV
- GV nhan xet, danh gid
va yeu cdu HS khai qudt kidn thflc
Hogt dpng cda HS + Dac diem tre mde hdi
chflng Dao.
- Dai dien HS trinh bay ->• ldp nhan xet.
Npi dung
- Hdi chflng benh NST:
Cac dot bidn cdu true hay sd lugng NST thudng lien quan den rdt nhieu gen, gay ra hang loat tdn thuang d cac he CO quan d ngudi ggi la hdi chflng benh.
* Tim hidu hdi chflng Dao.
- Nguyen nhan: Do thfla mdt NST cua cap sd 21 trong td bao (cap NST thfl 21 cd 3 chide), la loai dot bidn lech bdi. - Dac diem cua ngudi mde hdi chflng Dao. + Ngudi tha'p be, ma phe, cd rut, khe mdt xdch.
+ Dj tat tim va d'ng tieu hod.
+ Benh nhan cdn sd'ng dugc vi ft nghiem trgng. + Ti le sinh con mde hdi chflng Dao lien quan ddn tudi cua me.
Hogt dpng cda GV - GV neu cau hdi:
+ Tai sao tre bj Dao vdn sdng dugc thdi gian dai? + Vi sao ngudi me cao tudi sinh con thi ti le mde Dao cao, nhdt la sinh con ddu long?
- GV sfl dung thdng tin bd sung de md rdng kidn thflc ve tudi cua me vdi tan so sinh con mde hdi chflng Dao.
- GV neu yeu cdu: Em hay trinh bay hieu bidt cua minh ve benh ung thu.
Hogt dpng cda HS - HS thao luan nhdm.
- HS cd the tra ldi. + Cap NST 21 chfla ft gen, nhd nen su mat can bdng gen la ft nghiem trgng.
+ Tudi ngudi me cao qua trinh phan bao bj anh hudng, NST phan li khdng binh thudng.
Npi dung
- HS van dung kidn
thflc tfl thuc td va tu lieu sach bdo.
- Trao ddi trong nhdm. - Cd thd neu dugc. + Benh ung thu do cd khdi u ac tfnh gay nen. + Ti le tfl vong cao. + Khd phat hien hay da phat hien thudng da sd da d giai doan cud'i. + Mdt sd loai ung thu di truyen.
+ Hai lang ung thu d Phu Thg do d gdn cdc nha may san xuat boa chdt va chdt thai ddc hai.