215,6 nm va MA-4 (oxy-trans-resveratrol) CO hap thu cu,c dbi a btrac song 328,1 nm va 216,8 nm. Nhú vay c6 the chon 2 chat c6 ham luvng cao trong nguyen lieu lb moracin M (MA-1, 285 mg) va oxy-trans-resveratrol (MA-4, 1350 mg) lam chat
desi chieu de xay ding quy trinh djnh luvng d6ng thdri 2 host chat nay trong duvc lieu dau tem.
Ket Wen
Chiet met 9,5 kg canh duvc lieu dau tem thu duvc 356 g cao con. Phan lap duvc 3 chat ket tinh, tinh khiet tir cao ethyl acetat (35 g). Cac chat duvc xac djnh cau trim bang 1D-NMR va
2D, xac djnh là moracin M (285 mg), moracin
C (31,5 mg), oxy-trans-resveratrol (1350 mg). Trong d6 CO 2 chat CO ham luvng cao (moracin Trong d6 CO 2 chat CO ham luvng cao (moracin M va oxy-trans-resveratrol) se dúp'c chon sir
dung cho cac nghien tiep theọ
Tai lieu tham khao
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NXB Y hoc, tap 1, tr.710-712.
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Bioorganic & Medicinal Chemistry Letters, 22(9), pp. 3261-3264.
4. Deepa M. et al. (2012), "Purified mulberry leaf lectin (MLL) induces apoptosis and cell cycle arrest lectin (MLL) induces apoptosis and cell cycle arrest in human breast cancer and colon cancer cells",
Chemico-Biological Interactions, 200(1), pp. 38-44. 5. Hansawasdi C. and J. Kawabata (2006), "Alpha- glucosidase inhibitory effect of mulberry (Morus alba)
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7. Won-Gon Kim, Yu Kin Kim, Mi-Jin Sohn (2012), " Chalcomoracin and moracin C, new (2012), " Chalcomoracin and moracin C, new inhibitors of Staphylococcus aureus enoyl-acyl carrier protein reductase from Morus alba", Chemical & Pharmaceutical Bulletin, 35(5), pp. 791-795.
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(Ngdy nhOn bak 26/02/2015 - Ngay duyOt clang: 04/09/2015)