1. Chpn dap an D 2. Chpn dap an B
3. Viet cong thiic cau tao va gpi ten cac amino axit co cong thiic phan tir la C4H9NO2 CH3-CH2-CH-COOH NH2 CH3- CH-CH2- COOH NH2 CH2-CH2-CH2-COOH NH2 (fH3 C H 3 - C - C O O H axit 2-aminobutanoic axit 3-aminobutanoic axit 4-aminobutanoic axit 2-amino-2-metylbutanoic axit 3-amino-2-metylpropanoic NH2 NH2- CH2- C H - COOH CH3
Phuong trinh boa hpc
CH3CH(NH2)COOH + NaOH ^ CH3CH(NH2)COONa + H2O (1) CH3CH(COOH)NH2 + H2SO4 -^ [CH3CH(COOH)NH3]2S04 (2) CH3CH(NH2)COOH + CH3OH "^' ) CH3CH(NH2)COOCH3 + H2O (3)
CH3CH(NH2)COOH + HNO2 -^ CH3CH(0H)C00H + N2 + H2O (4)
Phuong trinh boa hpc
a) n H2N[CH2]6COOH - ^ ( HN-[CH2]6-CD )„ + nH20 "^^ ( HN-CH(CH3)-CD )n + nH20 b) n H2NCH(CH3)COOH -
6. Viet cac cong thiic cau tao ciia cac amino axit a) Axit 2-amino-3-phenylpropanoic (phenylanilin)
C6H5-CH2-CH-COOH NH2
b) Axit 2-amino-3-metylbutanoic (valin) (CH3)2CH-CH-COOH
c) Axit 2-amino-4-metylpentanoic (leuxin) (CH3)2CH-CH2-CH-COOH
NH2
b) Axit 2-amino-3-menylpentanoic (isoleuxin) CH3CH2-CH-CH-COOH
CH3 NH2 Phuong trinh h6a hpc
CH3CH(NH2)COOH + HNO2 -^ CH3CH(0H)C00H + N2 + H2O
X
CH3CH(0H)C00H "^^°^-'° > CH2=CH-C00H + H2O Y
CH2=CH-C00H + CH3OH ( ' '' > CH2=CH-COOCH3 + H2O 0,1 mol A tac dung voi 0,1 mol HCl cho 18,75 gam muoi
Mamino axil = 151 g/mol -^ c6 mot nhom NH2.
0,1 mol A tac dung voi NaOH cho 17,3 gam muoi
Mmu6i= 173g/mol ma Mamino axit = 151g/mol-> c6 mot nhom COOH.
Dat cong thiic ciia amino axit la NH2-CxHy-C00H -^ NH2-C7H6-COOH
Vi A la a-amino axit: A khong lam mat mau dung dich thuoc tim -> cong thiic ciu tao cua A la: C6H5-CH(NH2)-COOH.
Bai 13. PEPTIT VA PROTEIN
A. MUC TIEU B A I H O C 1. Kiln thu'c 1. Kiln thu'c
HS biit:
• Peptit, protein, enzim, axit nucleic la gi va vai tro ciia chiing trong co the
sinh vat.
• So luge ve cau tnic va tinh chat cua protein.
2. KT nang
• Nhan dang mach peptit. • Ggi ten peptit. (adsbygoogle = window.adsbygoogle || []).push({});
• Viet cac phuong trinh boa hpc cua protit va protein. • Phan biet cau tnic bac I va bac II ciia protein. • Giai cac bai tap phan peptit, protein.
3. Tinh cam, thai do
Qua noi dung bai, HS thay khoa hpc co the kham pha dugc nhimg hgp chat cau tao nen co the song va the gioi xung quanh, ciing co cho HS niem tin vao khoa hgc.
B. C H U A N Bj CUA GV VA HS
• GV: - May tinh, may chieu, cac philu hpc tap. - Hinh ve, tranh anh lien quan din bai hpc.
• HS: On tap kien thiic li thuyet, phuong phap giai bai tap vl (amino axit) va xem truoc bai (peptit va protein).