tumour necrosis factor aand lipopolysaccharide

... protein FXR1 controls post- transcriptional suppression of lipopolysaccharide- induced tumour necrosis factor- a production by transforming growth factor- b1 Tarnjit K. Khera 1 , Andrew D. Dick 1,2 and ... key mechanism of disease. Cytokine Growth Factor Rev 18, 335–343. 5 Waage A, Halstensen A & Espevik T (1987) Associa- tion between tumour necrosis factor in serum and fatal outcome in patients ... tumor necro- sis factors. Annu Rev Immunol 10, 411–452. 2 Beutler B, Greenwald D, Hulmes JD, Chang M, Pan YC, Mathison J, Ulevitch R & Cerami A (1985) Identity of tumour necrosis factor and the...

Ngày tải lên: 22/03/2014, 21:21

... opening is the key step in cell death that occurs during hypoxia and other conditions [9]. Tumour necrosis factor receptor-associated protein 1 (TRAP1) localizes to the mitochondria and its targeting sequence, ... (2010) 1929–1938 ª 2010 The Authors Journal compilation ª 2010 FEBS Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating ... also Keywords cardiomyocytes; cell damage; hypoxia; mitochondrial permeability transition pore; tumour necrosis factor receptor-associated protein 1 Correspondence Y S. Huang, Institute of Burn Research, State...

Ngày tải lên: 16/02/2014, 14:20

... Dulbecco’s medium; LPS, lipopolysaccharide; MSCs, mesenchymal stem cells; NF-jBp65, nuclear factor kappa Bp65; p38, p38 mitogen-activated protein kinase; TNF-a, tumour necrosis factor- a. 3688 FEBS ... potential paracrine roles of interleukin-1b (IL-1b), tumour necrosis factor- a (TNF-a) and interleukin-10 (IL-10), the expres- sion and secretion of these factors by rat bone marrow-derived mesenchy- mal ... Authors Journal compilation ª 2010 FEBS 3691 Expression and secretion of interleukin-1b, tumour necrosis factor- a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem...

Ngày tải lên: 18/02/2014, 04:20

... PARP, poly(ADP-ribose) polymerase; PKR, RNA-dependent protein kinase; TNFa, tumour necrosis factor- a; TRAIL, tumour necrosis factor- a-related apoptosis-inducing ligand; zIETD.FMK, zIle-Glu-Thr-Asp-fluoromethyl ... accepted 12 June 2006) doi:10.1111/j.1742-4658.2006.05374.x Tumour cells are often sensitized by interferons to the effects of tumour necrosis factor- a-related apoptosis-inducing ligand (TRAIL). We ... the tumour necrosis factor- a (TNFa) fam- ily are well known as inhibitors of cell growth and inducers of apoptosis in a wide variety of systems [1]. We have previously shown that both TNFa and tumour...

Ngày tải lên: 19/02/2014, 06:20

... K, Hauner H & Eckel J (1998) Tumor necrosis factor- alpha acutely inhibits insulin signaling in human adipocytes: implication of the p80 tumor necrosis factor receptor. Diabetes 47, 515–522. 7 ... glucose-6-phosphatase; Hnf-3, hepatocyte nuclear factor 3; PEPCK, phosphoenolpyruvate carboxykinase; TBP, TATA box-binding protein; TNFa, tumour necrosis factor- a. FEBS Journal 276 (2009) 3757–3769 ... functions [3–6] with well-described physio- logical effects [7]. One such adipocytokine is tumour necrosis factor- a (TNFa), which has been identified as a significant contributor to insulin resistance,...

Ngày tải lên: 16/03/2014, 02:20

... genotoxic stress and tumornecrosisfactoralpha.Cancer Res. 58, 1593–1598. 40. Liu, W., Bodle, E., Chen, J.Y., Gao, M., Rosen, G.D. & Broaddus, V.C. (2001) Tumor necrosis factor- related apoptosis- inducing ... Technology of China, Hefei, Anhui, China Tumour necrosis factor- related apoptosis-inducing ligand (TRAIL) has attracted much attention because of its ability to kill tumour cells. In this study, we demonstrated ... drug-resistant tumour cells, new meth- ods, which could bypass the resistance to chemotherapeutic drugs through activation of the death receptor-mediated pathway, need to be developed. Tumour necrosis factor- related...

Ngày tải lên: 23/03/2014, 17:22

... NF-jB, nuclear factor jB; PBMNC, mononuclear cells; PMA, phorbol 12-myristate 13-acetate; RPA, RNAse protection assay; TNF, tumor necrosis factor; TRAF, TNF receptor-associated factor. (Received ... Christian-Albrechts-University of Kiel, Germany To gain insight in the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF4) we analyzed GFP chimeras of full-length TRAF4 and various deletion ... TRAF4 in T-cells. Keywords:IKKc;NF-jB; T-cells; localization; TRAF4. The tumor necrosis factor (TNF) receptor-associated factor (TRAF) family comprises a group of adaptor proteins that are involved...

Ngày tải lên: 21/02/2014, 15:20

... of ETNF-6 mAb; HSA, human serum albumin; hTNF-a, human tumor necrosis factor- a; TNF-a, tumor necrosis factor- a; TNF-b, tumor necrosis factor- b; VIP, vasoactive intestinal peptide. FEBS Journal ... capable of digesting a targeting crucial protein that controls specific life functions. Tumor necrosis factor- a (TNF-a) is a cytokine and an important molecule concerned with autoimmune diseases ... ª 2010 The Authors Journal compilation ª 2010 FEBS 3827 Catalytic digestion of human tumor necrosis factor- a by antibody heavy chain Emi Hifumi 1,2 , Kyohei Higashi 3 and Taizo Uda 2,3 1 Research...

Ngày tải lên: 06/03/2014, 22:21

... tumor necrosis factor- a converting enzyme. Biochem. J. 357, 787–794. 33. Schlo ¨ ndorff, J., Becherer, J.D. & Blobel, C.P. (2000) Intracellular maturation and localization of the tumour necrosis ... Rolf Postina Institute of Biochemistry, Johannes Gutenberg-University, Mainz, Germany Tumor necrosis factor- a converting enzyme (TACE or ADAM17) is a member of the ADAM (a disintegrin and metalloproteinase) ... extracellular domains of different membrane-anchored signal proteins such as cytokines, growth factors, growth factor receptors and adhesion proteins [10]. The cellular mechanisms and signaling pathways...

Ngày tải lên: 08/03/2014, 02:20

... interferon; IRF-1, interferon regulatory factor- 1; NF-jB, nuclear factor- jB; shRNA, short hairpin RNA; TNF-a, tumor necrosis factor- a; TNF-R1, tumor necrosis factor receptor-1. 4396 FEBS Journal ... 4403 Tumor necrosis factor- a-induced caspase-1 gene expression Role of p73 Nishant Jain, Ch Sudhakar and Ghanshyam Swarup Centre for Cellular and Molecular Biology, Hyderabad, India Tumor necrosis factor- a ... events signal the recruitment of tumor necrosis factor- a receptor associated death domain to the intracellular death domain of TNF-R1. TNF-R1-bound tumor necrosis factor- a receptor associated death...

Ngày tải lên: 16/03/2014, 05:20

... compilation ª 2007 FEBS Luger TA et al. (1993) The 55-kD tumor necrosis factor receptor on human keratinocytes is regulated by tumor necrosis factor- alpha and by ultraviolet B radiation. J Clin Invest ... were interested to know whether factors involved in maintaining epidermal homeostasis affect DNp63a expression. We were par- ticularly interested in tumor necrosis factor- a (TNF-a), as this pleiotropic ... M, Chu CQ, Eedy DJ, Feldmann M, Bren- nan FM & Breathnach SM (1993) Localization of tumour necrosis factor alpha (TNF-alpha) and its recep- tors in normal and psoriatic skin: epidermal cells express...

Ngày tải lên: 16/03/2014, 06:20

... tensin homolog deleted on chromosome ten; NFjB, nuclear factor kappa B; TRAF, TNF receptor associated factor; TNF, tumor necrosis fac- tor; TNFR2, tumor necrosis factor receptor-2. P. J. W. Naude ´ et al. ... N-terminal kinase; NF-jB, nuclear factor kappa B; NIK, NF-jB-inducing kinase; RIP, receptor interacting protein; TNF, tumor necrosis factor; TNFR1 ⁄ 2, tumor necrosis factor receptor 1 ⁄ 2; TRADD, ... Pober JS (2001) Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 20, 6482. 78 Kalb A, Bluethmann H, Moore MW & Lesslauer W (1996) Tumor necrosis factor receptors (Tnfr)...

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