... of all of the enzymes of the pathway (Fig. 4), it is clear that only about half of the enzymes of the tricarboxylic acid cycle, the major pathway of carbon metabolism in mitochondria of oxygen-respiring eukaryotes, ... investigate the evolution of the enzymes of the pyru vate dehydrogenase (PDH) complex, the tricarboxylic acid cycle, and the glyoxylate cycle by examining t he individual phylogenies of the 21 s ... the t rees, and furthermore it will lead to the mutation of conserved motifs otherwise common to the sequence family to which the gene belonged at the time of endosymbiosis. The dissolution of...
Ngày tải lên: 22/02/2014, 04:20
... on the basis of our definition of RP as a fraction of the cell division cycle. The control coefficient of reaction step x on RP is the percentage change in the fraction of the cell cycle length ... E/Cdk2:p27. For each of the intermediates, the ratio of its gradient in the correla- tion plot and the gradient of cyclin E/Cdk2:p27 was close to the value of the co-control coefficient of the intermediate ... constructed their kinetic model on the RP of the mammalian cell cycle using a yeast-like core model of the cyclin–Cdk interactions (emphasizing the deep similarities of the Cdk-regulatory systems of yeast...
Ngày tải lên: 15/03/2014, 09:20
Báo cáo y học: "Study of the early steps of the Hepatitis B Virus life cycle"
... translocation of the internally sequence of PreS1 domain onto the viral surface [62, 63]. This supports the hypothesis that the low pH in the endosome may induce the conformation change of HBV surface ... a result of the variation of loading, because the expression of the thimet oligopeptidase gene in the same condition did not show any difference (Figure 2C). The over-expression of the SPIK ... particles, which is the majority of the two types [3, 4] The life cycle of HBV is believed to begin when the virus attaches to the host cell membrane via its envelope proteins. Then, the viral membrane...
Ngày tải lên: 03/11/2012, 10:09
The Steps of the Troubleshooting Cycle
... with the connected devices and the speakers are turned on. Gathering information is by far the most important step of the troubleshooting cycle. Step 3 Given the above scenario, what are the ... solution involves gathering correct information, knowledge of the computer components, and the ability to recognize symptoms. The problem has been isolated to a bad installation of the sound card. ... verifying the proper installation of the sound card in the PCI slot. If the problem still exists, check for system resource conflicts. Finally, update or reinstall the driver. Step 5 The first...
Ngày tải lên: 23/10/2013, 01:15
The thermodynamics of granular materials Sir Sam Edwards and Raphael Blumenfeld
... sparse then the original field of contact forces. Thus, a side effect of the parametrisation is that the field of loop forces is a coarse-grained version of the field of contact forces. In terms of the ... in two or that they are negligible for very soft 222 The thermodynamics of granular materials the grains, rather than the quadrons, were taken as the fundamental particles of the system. At present ... around individual voids. There are N of the former, one per grain, and M of the latter, giving altogether N + M dependent vectors. To determine the number 216 The thermodynamics of granular materials gg′ ρ g ρ gg′ r g g ′′ g ′ g ′′′ Fig....
Ngày tải lên: 01/11/2013, 08:20
Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc
... presenting the pulse of Src activity in the plane of the inactive and active fractions, s i and s 1 . If the duration of the stimulus exceeds the critical value, the trajectory in the (s i , ... steady states of the Src cycle. When there are three intersections, the steady state O 1 at the lower branch of the Z-shaped curve (i.e. low Src activity) and the state O 3 at the upper branch ... 2009 The Authors Journal compilation ª 2009 FEBS parameters and, for clarity of exposition, we present the analysis of the Src cycle in terms of Eqns (6–8). Intrinsic regulatory properties of the...
Ngày tải lên: 18/02/2014, 11:20
Báo cáo khoa học: Mathematical modelling of the urea cycle A numerical investigation into substrate channelling docx
... model of the urea cycle was previously written by one of us (P. W. Kuchel) [10], but aspects of channelling and the effects of subcompartmen- tation of the cycle were not explored. Hence, the aims ... amounts of unlabelled urea cycle intermediates were added to the cells, in order to assess the influence of these added substrates on the rate of urea synthesis. Model Written in Mathematica, the ... that 44% of the exogenous arginine had been hydrolysed by the end of the incubations (after 60 s). Fig. 3 plots the predicted time dependence of the concentration of added arginine for the first...
Ngày tải lên: 08/03/2014, 08:20
Increasing Aircraft Carrier Forward Presence - Changing the Length of the Maintenance Cycle pdf
... 24-month cycle, the fleet meets the goal only 76 percent of the time. e two-deployment cycles meet the goal more often: 88 percent of the time for the 36/42-month cycle and 99 percent of the time ... training and the sus- tainment of readiness, the FRP lengthened the carrier cycle from the notional 24 months of the IMP to 27 months. e FRP did not change the 6-month length of PIAs or the 10--month ... beginning with the end of the ship’s PSA. Fol- lowing the policy for the current 32-month cycle, the first DPIA for the 36/42- and the 42-month cycles are DPIA2s. e current 32-month cycle has one...
Ngày tải lên: 15/03/2014, 21:20
The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth Cycle potx
... strength of the relationship (i.e., how to proxy for the value of information obtained through the relationship). Most of the studies specified the duration of the relationship as the measure of its ... The results of some of the studies also suggested that in addition to duration, the strength of the relationship may also depend upon 1) whether the loan is drawn under a line of credit, 2) the ... breadth of the relationship (whether it extends to deposits and other services), 3) the size of the borrowing firm and its outside finance options, 4) the structure of the banking industry, and 5) the...
Ngày tải lên: 15/03/2014, 21:20
Being Born Under Adverse Economic Conditions Leads to a Higher Cardiovascular Mortality Rate Later in Life: Evidence Based on Individuals Born at Different Stages of the Business Cycle pdf
... Mathe- matical Biosciences 198, 1–13. 37 4.3 Sensitivity analyses and additional results 4.3.1 The effect of the timing of the birth in the year and the business cycle around the birth year The ... on the correlation ρ between the unobserved determinants, as the latter is the only source of correlation of the former. Secondly, the presence of a within- twin pair correlation between the ... it into the constant term of β x. As a result, the joint distribution of V 1 , V 2 has two parameters: the variance σ 2 of V i and the correlation ρ of V 1 and V 2 . The latter equals the fraction...
Ngày tải lên: 17/03/2014, 08:20
Báo cáo Y học: Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle potx
... fact, w e Ó FEBS 2002 The fate of hCDC6p during the HeLa cycle (Eur. J. Biochem. 269) 1041 Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle Esther Biermann, Martina ... chromatin-bound h Cdc6p. The presence of hCdc6p in these preparations was determined by immunoprecipitation. Rates of hCdc6p synthesis To investigate w hether the synthesis of hCdc6p was restricted ... for 2 h at the beginning (0–2 h after thymidine-block) and in the middle of S phase (4–6 h), as well as at the e nd of mitosis and during the early G1 phase (12–14 h) of the next cycle (Fig....
Ngày tải lên: 17/03/2014, 23:20
Pulp Fact Environmental Implications of the Paper Cycle docx
... wrapping. __________________________________________________________________________________________ • More than half the world's exports of paper come from Canada (over a fifth of the total), Finland, Sweden and the US. The US is also a major importer. The main Northern exporters of pulp are ... resource consumption. These criticisms gained official recognition in the UK, with criticism of high targets for recycled paper made by a Select Committee of the House of Lords 180 . 26 • Pulp ... Recovering the print-run of the Sunday edition of the New York Times would leave some 75,000 trees standing. Some 15 million tonnes of wood are thrown away every year worldwide in the form of disposal...
Ngày tải lên: 18/03/2014, 02:20
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES - Full cost accounting for the life cycle of coal potx
... accounting for the life cycle of coal Epstein et al. emissions from coal mines, on the order of 3% of the stack emissions. 110 There a re also additional GHG emissions from the other uses of coal, ... measure of the costs of climate change is the rising costs of extreme weather events, though these are also a function of and real estate and in- surance values. Overall, the costs of weather-related disasters ... estimates of the social cost of carbon the valuation of the damages due to emissions of one metric ton of car- bon, of $30/ton of CO 2 equivalent (CO 2 e), 20 with low and high estimates of $10/ton...
Ngày tải lên: 23/03/2014, 00:20
Environmental Impact of Products (EIPRO) Analysis of the life cycle environmental impacts related to the final consumption of the EU-25 pot
... some of the products investigated. Most of the data used is from the end of the 1990s, with 2000 as the reference year. New policy initiatives cannot therefore be initiated on the results of ... agencies. These tables, in the form of matrices, describe production activities in terms of the purchases of products 12 of each industrial sector from all other sectors. They cover the entire ... and how waste is then treated in the life cycle modeling of the other product groupings. 21 Environmental Impact of Products (EIPRO) • Chapter 4 forms the first main pillar of the study: it makes...
Ngày tải lên: 23/03/2014, 08:21
Báo cáo Y học: Thermodynamics and kinetics of the cleavage of DNA catalyzed by bleomycin A5 A microcalorimetric study pdf
... cleaving potential of the remaining molecules. The impact of self-inactivation of activated BLM on the thermodynamics of DNA binding is more complex. As the structural identities of the BLM degradation ... ð20Þ Thermodynamics and kinetics of the cleavage of DNA catalyzed by BLM-A 5 From the spectroscopic results, the ratio of the absorbance at 260 nm to that at 280 nm for purified DNA used in the present ... sets of experimental data (x and t) and using the MATHSOFT MATHCAD software (version 2001). The value of s, the lifetime of self-inactivation, was calculated using the rate constant k 1 . A thermodynamic...
Ngày tải lên: 24/03/2014, 04:21
BUSINESS CYCLES: A Theoretical, Historical and Statistical Analysis of the Capitalist Process potx
Ngày tải lên: 29/03/2014, 19:20
lieb, yngvason. physics and mathematics of the 2nd law of thermodynamics
Ngày tải lên: 24/04/2014, 17:14
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