... than 70 at the time of the interview, 74,942 women remained for the SWHS. The major reasons for non-participation were refusal (3.0%), absence during the enrolment period (2.6%), and other miscellaneous ... Incident type 2 DM was identified through the follow-up surveys. A total of 1972 new cases of type 2 DM were reported. For the current study we considered a case of type 2 DM to be confirmed if the ... positively associated with the risk of type 2 DM. There was an indication that the effect of unprocessed meat intake on type 2 DM may be modified by BMI. Key words: type 2 diabetes, meat intake,...
Ngày tải lên: 31/10/2012, 16:49
... English Theme is the first element of a clause and providing what we call the departure for the starting point for the clause. By changing Theme we do not change the ideational meaning but the ... which they are involved? + The MODE OF DISCOURSE concerns what part the language is playing, what it is that the participants are expecting the language to do for them in that situation, the symbolic ... (1997: 7-8) 5. 3 The nominal group The metafunctional organization of the grammar that we illustrated above for the clause applies to the other ranks as well. For example, the nominal group...
Ngày tải lên: 07/11/2012, 14:44
Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-fin eelpout, Zoarces elongatus Kner ppt
... then adsorb to the ‘open space’ between the prebound AFPs of the ice crystal surface; (c) most of the nfeAFP isoforms adsorb to the growth-terminated ice crystal in the final state. This hypothesis ... recently reported that the increase in activity of the type III AFP multimer results from an increase in the size of the ice-binding surface. These results suggest that, although the monomer of nfeAFP13 ... respectively. The information on the com- plete sequence analyzed for peak 2 allowed us to iden- tify that the isoform belongs to the type III AFP the N-terminus of which is unblocked, probably the SP group...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo Y học: The Fc receptor c-chain is necessary and sufficient to initiate signalling through glycoprotein VI in transfected cells by the snake C-type lectin, convulxin ppt
... illustrates the dual mechanism of the complex, with one subunit, namely GPVI, responsible for binding to the ligand, and the other subunit, the FcR c-chain, responsible for transmission of the signal ... the importance of the arginine residue in the transmembrane domain of the immunoglo- bulin receptor. However, the cytoplasmic domain of these FcRs is not essential for binding to the FcR c-chain. ... both the transmem- brane arginine and at least part of the cytoplasmic tail for its association with the FcR c-chain, although it is not clear how the cytoplasmic tail supports the association. The molecular...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo " On equations of motion, boundary conditions and conserved energy-momentum of the rigid string " doc
... integrations. The Z-terms in formula (9) for δS can be regarded as a contribution from the corner points of the rectangle R. For the closed string they cancel each other. However, for the open string they ... rigid string we encounter a coincidence of the following two mathematical obstacles: the presence of the high derivatives in the Lagrangian , and the fact that the field x µ (τ, σ) is defined on the ... (17) In the case of the closed string δ µ (τ, σ) obey the conditions δ µµ (τ, σ = 0) = δ µ (τ, σ = σπ). Then, the variation principle implies only the equations motion (13). Now, let us pass to the...
Ngày tải lên: 05/03/2014, 14:20
Báo cáo khoa học: Enzymatic investigation of the Staphylococcus aureus type I signal peptidase SpsB – implications for the search for novel antibiotics ppt
... lower than the pK a of lysine in solution. The reason for the decreased pK a of the active-site lysine in the SPases is not known. It is also unclear whether the hydrophobic environment of the membrane ... and therefore the FRET assay was used to study the effect of pH on the enzyme. The stability of the synthetic SceD peptide substrate was determined by incubating it in different buffers in the ... the Western Star TM kit (Tropix, Bedford, MA, USA) in accordance with the manufacturer’s instructions. Specificity of the cleavage of the SceD peptide by SpsB The synthesis and validation of the...
Ngày tải lên: 07/03/2014, 01:20
Báo cáo khoa học: Effect of annealing time of an ice crystal on the activity of type III antifreeze protein pdf
... type III AFP, enabling complementary binding to the flat ice prism plane [14,21]. When the type III AFP solution contains a seed ice crystal, the AFP molecules come closer to the ice through the ... used to check the perfor- mance of the photosystem. We initially placed a 50 lL sam- ple into the cooling bath ()7 °C) of the osmometer. When the sample temperature reached )7 °C, the instrument automatically ... the crystal size at the fast cooling rate. These results imply that the cooling rate dominates the TH dependence on the seed crystal size. As actual tem- perature control of the freezing plate...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo Y học: The Saccharomyces cerevisiae type 2A protein phosphatase Pph22p is biochemically different from mammalian PP2A potx
... of inhibitors reflecting the high degree of conservation of the catalytic core between these two enzymes and ruling out the involvement of the N-terminal extension in binding to these inhibitors. As ... and the induction was carried out for 9 days. To determine the optimal time for protein expres- sion, aliquots of the cultures were removed at 24-h intervals and analyzed for the presence of the ... enzymatic activity. The stimulation of catalytic activity of Pph22p by protamine and polylysine reflects the stimulation of the mammalian PP2Ac-PR65/A dimeric form of the phosphatase. The N-terminus...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: The refolding of type II shikimate kinase from Erwinia chrysanthemi after denaturation in urea pot
... step is the fifth in the seven-step pathway leading to the synthesis of chorismate, the precursor of aromatic compounds. From the X-ray structure of SK [15], it is clear that the ordering of the strands ... Ônative -type shikimate binding site and the consequent quenching results in the overall decrease in fluorescence in this phase of the process. The simplest interpretation of these results is that the ... LDH. From the decrease in A 340 ,the concentration of ADP produced in the SK-catalysed reaction at the chosen times can be determined, and hence the rate of this reaction calculated. The errors...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: Enzymatic oxidation of NADP+ to its 4-oxo derivative is a side-reaction displayed only by the adrenodoxin reductase type of ferredoxin-NADP+ reductases potx
... distinct subgroups: the mitochondrial -type and the plastid -type (or plant -type) enzymes [1]. The prototype of the former enzymes is the mammalian adrenodoxin reduc- tase (AdR), whereas the latter subgroup ... Hypothetical mechanism of the reductive half-reaction of the catalytic cycle of FprA in the oxidation of NADP + to yield NADPO. The reaction scheme was based on the crystal structures of the ... O 2 . In any case, the produc- tion of H 2 O 2 and ⁄ or O 2 – strongly supports the FAD prosthetic group as the direct oxidant of the nicotina- mide ring, as these species are the usual products...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: SOX10, in combination with Sp1, regulates the endothelin receptor type B gene in human melanocyte lineage cells pptx
... abnormal pigmentation of the hair and skin. WS type 4 (WS4), a subtype of WS, is characterized by the presence of the aganglionic megacolon and is associ- ated with mutations in the gene encoding either endothelin ... representation of the EDNRB promoter. The number represents the posit- ion from the transcriptional initiation site (+ 1) of the EDNRB gene. The two CA-rich sequences and the GC box are marked. The CA1 ... the autoradiograph of the EMSA by using the GC1 ⁄ CA2 probe. The recomb- inant Sp1 was used. The competitors used are wild -type probe or the mutated probe (shown as Fig. 4A). The consensus Sp1 binding...
Ngày tải lên: 16/03/2014, 13:20
The Awassi sheep with special reference to the improved dairy type potx
... hot months of the year is their fleeces, the pigment of their heads and their habit of keeping their heads in the shade below the bellies of their flock mates. It is only from the cold storms ... in the tail was distributed over the body in the form of fat and muscle tissue. In other words, the body of the fat-tailed lambs was leaner by nearly the whole amount of their tail fat than the ... recorded the changes in the length and thickness of the teats of 24 Awassi ewes in the course of the milking process. The length of the teats was measured with a caliper from the base to the tip...
Ngày tải lên: 18/03/2014, 00:20
Báo cáo Y học: Importin a binds to an unusual bipartite nuclear localization signal in the heterogeneous ribonucleoprotein type I pptx
... GDP-bound forms of Ran between the cytoplasm and the nucleus, with the GTP-form predominant in the nucleus [12,13]. Based on the similarities of their primary structures, the importins a have been ... upstream of the larger cluster. The Table 1. Bipartite type nuclear localization signal. The single-letter amino acid code is used. The bold letters indicate the two arms of basic residues of the bipartite ... contain the NLS-binding site and importins b are responsible for the docking of the importin–substrate complex to the cytoplasmic side of the NPC and its subsequent translocation through the pore....
Ngày tải lên: 18/03/2014, 01:20
Difficult People A Practical Guide to Dealing With the 10 Main Types ppt
... to others. This will in turn make the person seem like an egotist in the negative sense, and it will not really bring them the respect and the feelings that they want to feel from others they ... Power The Art To Influencing Difficult People How To Handle These Difficult People The Intimidator The Stealth Bomber The Oscar Goes To Person The Bombastic Blowhard The Politician The Yes People The ... using the individuals name is the best approach. If you keep using their name they will discuss their concerns, and you can resolve the issues they have. Over time the person will calm down when they...
Ngày tải lên: 20/03/2014, 19:20
the geometrical setting of gauge theories of the yang-mills type
Ngày tải lên: 24/04/2014, 17:17
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