... cleavage ofthe p220 component ofthe cap-binding protein complex [32], resulting in the shut off of host protein synthesis On the other hand, the function of L ofthe cardioviruses is not well ... protease of foot -and- mouth disease virus J Virol 1 986 , 58: 893 -89 9 Piccone ME, Zellner M, Kumosinski TF, Mason PW, Grubman MJ: Identification ofthe active-site residues ofthe L proteinase of foot -and- mouth ... inhibit the iron/ferritinmediated activation of NFκB [34] The functions of L of Page of (page number not for citation purposes) Journal of Neuroinflammation 2006, 3:19 TMEV andthe other cardioviruses...
... evaluated the cleavage pattern ofthe 5'-32P-RNA strand ofthe duplex by wild-type enzymes andtheir chimeric derivatives As shown in panel A of Figure 5, the initial cleavage ofthe 30-mer RNA strand ... 221 100 (4500) 91 71 1 08 65 100 (3740) 69 95 183 68 100 (2721) 46 58 81 48 100 (2451) 58 68 72 52 The polymerase activities of wild-type reverse transcriptase enzymes andtheir chimeric derivatives ... influenced the stringency of substrate dNTP selection We analyzed the pattern of synthesis and extension ofthe various mispairs by the chimeric enzymes and compared them with those ofthe wild-type...
... reading 13 2.4.2 The role ofthe teacher andthe students in teaching and learning Reading 13 2.4.2.1 The role ofthe teacher 13 2.4.2.2 The role ofthe students 14 ... Rationales ofthe study 1.2 The aims ofthe study 1.3 Research questions 1.4 Scope ofthe study 1.5 Methods ofthe study 1.6 Significance of ... 4.3.2.1 The role of reading skill to the students‟ learning English and future career 35 4.3.2.2 The role of reading materials to the motivation for learning reading skill 36 4.3.2.3 The students‟comments...
... lesson, the students play the role ofthe readers They need to understand how texts work and what they when they read It is the fact that the student is the heart ofthe reading lesson andthe element ... another way to helps the students understand the content ofthe text while 18% of them say that by reading only the first andthe last sentence ofthe teachers paragraph, the students can know the ... duties On the other hand, the students are the providers of feedback to the teacher through their expression and understanding ofthe reading texts Without the students‟ feedback, the teacher...
... significance ofthe study and methods ofthe study Chapter deals with an overview ofthe theoretical background ofthe research It is concerned with the issues relevant to the topic ofthe research ... college Chapter 5, the last chapter ofthe study, is the conclusion where all the main contents ofthe study are summarized and limitations ofthe study and suggestions for further studies are ... learning One ofthe major concerns of educators and parents is motivating students so that they work at the best oftheir abilities ( Guthrie, Solomon 1997) The key is to motivate them in such...
... cause of offence In these habits we resemble the Aborigines of our country They load their huge pipes with the dried leaves of this plant, and when lighted, they breathe the dark cloud of smoke ... men void of understanding; capable of soothing the sorrows ofthe afflicted, of healing the wounds ofthe spirit, and assuaging the anguish of a broken heart But how it fulfils these desirable indications, ... meeting ofthe Medical Society ofthe County of Oneida, on the 5th of March, 183 0, a communication was received, signed by a numberof highly respectable gentlemen from this and other counties of...
... One of these shielded nuclei is a gamma proton of P 68 with a chemical shift of )0.32 ppm Tellingly, the gamma protons ofthe structurally related P 98 in a-sarcin also have low d values ()0 .83 and ... ofthe active-site residues ofthe 20 conformers ofthe solution structure of HtA Catalytic groups E66 and H113 are shown in red, and side chains of other residues in their vicinity are shown in ... should affect their pKa values, increasing the pKa of carboxylates and decreasing the pKa of histidines [24] Structurally, the architecture ofthe active site in HtA is unique among the ribotoxin...
... O 28 and R14 was much lower compared to that of P mirabilis G1 and S1959 andthe structures oftheir O-polysaccharides are significantly different [21,27] Therefore, in spite ofthe occurrence of ... migrating bands of all LPS tested and slow migrating bands of P mirabilis S1959, G1, and O 28 LPS, the banding patterns being clearly different (Fig 5B) These findings together showed that the epitope ... fi L-Lys 4.55 4.51 4.02 3 .89 3 .85 3 .80 4.12 4.03 3.70 3 .85 3. 78, 3. 78 3 .89 , 4.16 102.4 102 .8 52.3 53.2 81 .3 71.1 69.0 75.9 76.1 73.4 62.4 66.7 4.53 5.20 3.36 3 .86 4. 38 3.56 4.05 1.79, 1.91 3.73...
... 36% ofthe interaction ofthe full peptide with the binding cavity of SM3 The sizes ofthe surfaces were determined using distances between ligand ˚ atoms and protein atoms of less than A These ... a distance of A or less to the ligand The C-terminal part ofthe peptide (RPAP) has close contacts to the next protein in the crystal cell and is therefore stabilized on the surface of SM3 It ... obtain a 3D picture with the binding residues ofthe ligand identified in their relative orientation in space and thus efficiently optimize on the structure ofthe ligand for further immunization studies...
... group of cytosine (C8) overlaps with C7 and, O2 of C7 overlaps with C8 On the other hand, sustained stacking persists by way of partial overlap of T7 and C8 (Fig 2F) at the corresponding TC(7 8) ... steps ofthe PNA strand, flanking the A24 C7 mismatch in PDwt (Scheme 1), andthe corresponding AT(6–7) & TC(7 8) steps ofthe DNA strand (Fig 2E,F), and GA(23–24) & AT(24–25) (Fig 2G,H) steps ofthe ... PDmut On the other hand, stacking at the AC(6–7) step in the DNA strand of PDwt is retained during the entire simulation in spite ofthe large movement of C7 (Fig 2A) This occurs due to the coordinated...
... be girls) and they have been friends all their lives They grew up playing together on the street, riding their bicycles and pulling pranks on other kids As they start to get older they start ... do, then you can express this to them before it actually happens and they can decide whether they accept this as fair or not If they do, then there will be no problems as they will know their ... part ofthe excitement for women in new relationships is trying to get their man to be how they want them to be in certain ways They love the challenge of changing a guy and it excites them Now,...
... [23] The CL2 chloride site is absent in ACE2 as a result of substitution ofthe tACE residues Pro407 and Pro519 with Glu3 98 and Ser511, andthe resulting projection oftheir side-chains into the ... mutagenesis of CL1 and CL2 site residues of tACE and ACE2 The residues surrounding the chloride ion at the CL1 and CL2 sites of tACE and ACE2 are shown in Fig In tACE, the residues that coordinate the ... chloride ion at the CL1 site are Arg 186 , Trp 485 and Arg 489 , which are conserved as Arg169, Trp477 and Lys 481 in ACE2 [22,24] All of these residues can influence chloride binding and therefore the chloride...
... for the eye The dashed line corresponds to the band-gap for the undoped Si-nw Fig 11 shows how the FE for the B and P codoped Si-nw changes as function ofthe position ofthe dopants within the ... asymptotically the value ofthe band-gap ofthe undoped Si-nw This is another indication of how doping can modify the electronic and optical properties ofthe Si nanostructures Conclusions 3.2 3.4 3.6 3 .8 ... energies andthe excitonic effects through the solution ofthe Bethe-Salpeter equation (BSE) [34] The effect of local fields is also included, to take into account the inhomogeneity ofthe systems...
... position ofthe signals for C6 of GlcNAc (d 69.9), C3 of GalNAc (d 77.5), C4 of Qui3NAc (d 77.5) as well as C2 and C4 of GalA (d 77.2 and 81 .8, respectively), as compared with their position in the ... carbons in the region d 68. 8 81 .8, and three N-acetyl groups at d 23.4–23 .8 (CH3) and 175.1–176.0 (CO) Accordingly, the 1H NMR spectrum ofthe polysaccharide contained signals of equal intensity for ... of GalA GLC analyses ofthe acetylated (S)-2-(+)-butyl glycosides demonstrated the d configuration of Glc, GlcN, GalN, and GalA The d configuration of Qui3N was established by the analysis of the...
... found the radiolabeled oxygen at the Ca and Cb positions in a comparison ofthe mass spectrum with that ofthe products ofthe reaction with GG and unlabeled water The incorporation of 18O from ... atmosphere of 18O2 and analysed the reaction mixture by GC-MS Figure shows the mass spectrum of GG; no 18O were found in the reaction products Therefore, we examined the incorporation ofthe water ... characterized the b-etherase andthe nucleotide sequences ofthe ligE and ligF genes of S paucimobilis SYK-6 [13] b-Etherase is a member ofthe glutathione-S-transferase superfamily [14] It catalyzes the...
... ofthe poor, the aggressions ofthe rich, the multiplication and ferocious treatment of slaves, andthe social rivalries ofthe capital, the condition of Italy andthe general deterioration of ... their generals but mock them when at the head oftheir armies they exhort their men to fight for their sepulchres andthe gods oftheir hearths, for among such numbers perhaps there is not one Roman ... the shores ofthe Sea of Azof; or were they the Homeric Cimmerii who dwelt between the Dnieper andthe Don? Or did their name indicate their CHAPTER V 37 personal qualities, and not their previous...
... ofthe RM is chosen to be the same as the MNI ofthe SM In this case, when the values of all the parameters ofthe set P are strictly equal to their counterparts in the set p andthe values of ... cartesian coordinates ofthe position ofthe receiver on the ground and (0, 0) the position ofthe emitter, also on the ground, ofthe probe signal The present study is restricted to the case in which ... P are strictly equal to their counterparts in the set p andthe values of all the parameters ofthe set N are strictly equal to their counterparts in the set n, then the inversion will give rise...