symmetric vs asymmetric cell division

... Introduction Asymmetric cell division Asymmetric cell division is an important cellular process whereby a single cell divides via mitosis to two different daughter cells While symmetric divisions ... transit amplifying cell can further divide asymmetrically to regenerate itself as well as to produce a GMC 9|Page Introduction Asymmetric cell division in neuroblast Asymmetric cell division in the ... in stem cells where asymmetric cell division of the stem cell would produce two distinct daughter cells: one committed cell or differentiated cell and another which remained as a stem cell This...

Ngày tải lên: 10/09/2015, 08:33

... ASYMMETRIC CELL DIVISION IN VERTEBRATES Most of the current knowledge about asymmetric cell division in vertebrates is derived from embryonic progenitor cells in the developing brain Asymmetric cell division ... INTRODUCTION ASYMMETRIC CELL DIVISION 1.1 ASYMMETRIC CELL DIVISION IN CAENORHABDITIS ELEGANS 1.1.1 Establishment and Maintenance of the Anterior-Posterior (A-P) axis 1.1.2 Asymmetric spindle ... may also have role in cell cycle regulation and development x Chapter Introduction Chapter Introduction Chapter 1 Introduction ASYMMETRIC CELL DIVISION Asymmetric cell division (ACD) is a highly...

Ngày tải lên: 11/09/2015, 14:32

... regulation of asymmetric cell division to self-renew and to differentiate Figure Regulation of stem cell division A Symmetric versus Asymmetric cell division Symmetric division is adopted by many cell ... defective asymmetric cell division, one needs to first understand the mechanisms regulating asymmetric cell division 1.7 Drosophila Stem Cell self-renewal and Tumor suppression Recent studies of asymmetric ... divide asymmetrically as well, albeit in a slightly 1.4 Asymmetric cell division in Drosophila neural stem cell Many key components of the genetic machinery that facilitate asymmetric division...

Ngày tải lên: 11/09/2015, 14:32

... types of cell division: symmetric and asymmetric The symmetric cell division produces two identical daughter cells that acquire the same developmental fate The main purpose of symmetric divisions ... of cell populations The asymmetric cell division gives rise to two daughter cells with different developmental fates and generates cell diversity from bacteria to mammals The asymmetric cell division ... oogenesis The cell polarity and asymmetric cell division in vertebrate 30 33 37 3.1 Asymmetric cell divisions during neurogenesis in developing vertebrate central nervous system 3.2 Establishing cell...

Ngày tải lên: 15/09/2015, 17:11

... invertebrate homologues In particular, studies of cell division cycle protein 48 (Cdc48p) in Saccharomyces cerevisiae have uncovered roles in many cellular processes, including membrane fusion [18], ... of these processes for cell survival More specifically, S cerevisiae Cdc48p interacts with Ufd2p, the homologue of Ube4b [11], so S cerevisiae is used as a model for invstigating the role of VCP ... whether VBM-dependent complexes form in living cells Transiently transfected FLAG-tagged wild-type Atx-3 was able to coimmunoprecipitate VCP from HeLa cells, whereas R282A Atx-3, which lacks a functional...

Ngày tải lên: 18/02/2014, 13:20

... in the genome suggests a regulatory role in mycobacterial cell division Alteration in cell shape is the initial event in bacterial cell division which involves ordered assembly of proteins [34,35] ... regulating morphological changes associated with cell division Finally, our study in a heterologous setting has shown the involvement of PknA in cell shape regulation; it is the first report describing ... C.P Jr (1998) Control of cell shape and elongation by the rodA gene in Bacillus subtilis Mol Microbiol 28, 235–247 33 Begg, K.J & Donachie, W.D (1985) Cell shape and division in Escherichia coli:...

Ngày tải lên: 22/02/2014, 04:20

... C-terminally duplicated C2 -symmetric and asymmetric inhibitors in complex with the HIV-1 protease These compounds, including the C2 -symmetric ones, were found to bind in an asymmetric fashion Ki values ... substrate, the inhibitors, including the symmetric ones, tend to bind in an asymmetric fashion [40,42] Compounds 3, and were made in order to exploit the asymmetric binding Electron density maps ... the catalytic residues (Asp25/Asp125) However, a symmetrical arrangement of the central hydroxyls was not found for either the symmetric or the asymmetric compounds Instead, one of the hydroxy...

Ngày tải lên: 08/03/2014, 02:20

... required for cell division of plant cells in vitro Several lines of evidence suggest that cytokinins also play key roles in the regulation of cell division in vivo Much of the cell division in ... or protuberance near the apical ends of specific cells (Figure 21.15) An asymmetric cell division follows, creating the initial cell The initial cell then divides mitotically to produce the bud, ... Differentiated Plant Cells Can Resume Division Under some circumstances, mature, differentiated plant cells may resume cell division in the intact plant In many species, mature cells of the cortex...

Ngày tải lên: 16/03/2014, 22:20

... Rothfield L (1992) The essential bacterial cell- division protein FtsZ is a GTPase Nature 359, 254–256 30 RayChaudhuri D & Park JT (1992) Escherichia coli celldivision gene ftsZ encodes a novel GTP-binding ... Glutamate-induced assembly of bacterial cell division protein FtsZ J Biol Chem 278, 3735–3741 Yu XC & Margolin W (1997) Ca2+-mediated GTPdependent dynamic assembly of bacterial cell division protein FtsZ into ... red induced bundling of bacterial cell division protein, FtsZ J Biol Chem 279, 25959–25965 Erickson HP, Taylor DW, Taylor KA & Bramhill D (1996) Bacterial cell division protein FtsZ assembles into...

Ngày tải lên: 30/03/2014, 16:20

... extended sense of "animal or plant cell" [because cells were originally thought to be hollow]) - Karyo- (pre.): (Greek) nhân - Kinesis (suf.): di chuyển, động - Cell division (n): phân bào, bao gồm ... pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage Cell 125, 85–98 (2006) Ghi chú: - Cytokinesis (n): bào phân, nói phân chia tế bào chất sau phân ... biết rõ Theo báo cáo tạp chí Cell, Barral cộng phát đường truyền tín hiệu – gọi NoCut- làm nhiệm vụ cản trở hoàn tất bào phân...

Ngày tải lên: 02/07/2014, 14:20

... of cells in the three phases of the cell cycle–G1, S, and G2/M–were evaluated by the Partec software When cell division indices (ratio of G2M% vs G1%) were compared, the portion of wild-type cells ... central to controlling cell differentiation as well as division Populations of dividing cells are smaller in the roots of dwf7-1 relative to wild-type cells To examine cell division in the roots ... cell division is delayed due to decreased BR activities in this mutant Genes of BR biosynthesis and cell division show differential expression patterns To understand the differences in cell division...

Ngày tải lên: 11/08/2014, 11:21

... organism 1.2 Asymmetric cell division versus symmetric cell division 1.3 Asymmetric cell division in Caenorhabditis elegans 1.4 Asymmetric cell division in Drosophila melanogaster CNS 1.4.1 Asymmetric ... 1.6 Cytoskeleton elements are involved in asymmetric cell division 52 1.7 Cell cycle regulation during asymmetric cell division 53 1.8 Asymmetric cell division in vertebrate neurogenesis 54 1.9 ... of asymmetric cell divisions (a) Symmetric cell division Two daughters inherit same cellular components including cell fate determinant (green) and adopt the same fate (b and c) Asymmetric cell...

Ngày tải lên: 12/09/2015, 09:55

... What is a Cell?  Cell – Basic unit of living things Organisms are either:  Unicellular – made of one cell such as bacteria and amoebas OR  Multicellular – made of many cells such as plants ... scientists believe to be true about cells:  Cells are the basic unit of life  All living things are made of cells  New cells are produced from existing cells Microscopes  Light Microscope – magnifies ... multicellular organisms Ex: animals, plants, fungi Prokaryotes NO nucleus NO membrane bound organelles (just ribosomes) ALL are unicellular Smaller than eukaryotic cells Forerunner to eukaryotic cells...

Ngày tải lên: 13/03/2014, 18:04

... mobility and phagocytosis Tumour-infiltrating dendritic cells and tumour associated macrophages counter BCG- effects [16,17] Natural killer cells and macrophages are viewed as important targets ... tumour cells The antitumoural properties of IFNγ-activated macrophages have been demonstrated in vitro in experimental murine models of human tumours [23] Monocytederived activated killer (MAK) cells ... intrapleural infusion of MAK cells have been assessed in mesothelioma [24] and residual peritoneal ovary carcinomas [25] A prior phase I trial of autologous MAK cells (BEXIDEM®) in patients with...

Ngày tải lên: 18/06/2014, 16:20

... in cell proliferation, cell adhesion, cell migration, and cell differentiation [37] and is up-regulated in many tumors [38] Although not much is known about its role in cis-platin induced cell ... and 5% CO The cell lines were sub-cultured on routinely basis every 3-4 days Cell viability assays A2780 and A2780/CP70 cell lines were cultured to test the responsiveness of each cell line to ... are displayed as mean ± SD Figure Cell proliferation assay of A2780 and A2780/CP70 cells Viability of cells were assessed after 72 h in A2780 and A2780/ CP70 cell lines post cis-platin treatment...

Ngày tải lên: 20/06/2014, 08:20

... fraction of large, PI negative cells (lower right quadrants) which represents viable, intact cells For each measurement, a total of 10.000 cells was analyzed Immunoblots Cells were collected and lysed ... analyzed microscopically, both untreated cell lines uniformly displayed an intact cell morphology with round cells and almost no irregular shapes or cell debris (Fig 1B, left panels) As expected, ... of the cells were taken to document their morphology Prior to stimulation, the cells were preincubated for 60 with 50 μM zVAD-fmk As representative examples, one healthy cell and one cell undergoing...

Ngày tải lên: 09/08/2014, 10:20

... far, establishing RVs as the most diverse group of Picornaviridae [9,10] Based on receptor binding properties, RVs are divided into two classes: the major group binding to intracellular adhesion ... important cytokine responsible for cell mediated immunity [25] It is primarily produced by T-helper lymphocytes but is also derived from cytotoxic T cells and NK cells IFN-gamma production belongs ... cytokine production by cell lines from human mast cells and basophils J Immunol 2002, 169(3):1482-1491 Jakiela B, Brockman-Schneider R, Amineva S, Lee WM, Gern JE: Basal cells of differentiated...

Ngày tải lên: 12/08/2014, 14:20

... significant difference in cell numbers were detected in the “collapsing” vs “expanding” PLN [29] We also failed to detect any significant difference in the B-in population in terms of cell numbers, gene ... collapsed PLN [29] Additionally, B cell depletion therapy with anti-CD20 antibodies sustained high LNCE of PLN, and anti-CD20 antibody treated TNF-Tg mice did not display asymmetric arthritis similar ... mice Here we examined the association of asymmetric TNF-induced knee arthritis with: i) ipsilateral PLN and ILN collapse, ii) translocation of CD23+/CD21hi B cells (B-in), and iii) decreased afferent...

Ngày tải lên: 12/08/2014, 17:22

... mammalian cell size BMC Cell Biol 2004, 5(1):35 Prescott DM: Relations between cell growth and cell division I Reduced weight, cell volume, protein content, and nuclear volume of Amoeba proteus from division ... pattern of cell growth What is the expected pattern of cell growth during the division cycle? The overwhelming majority of a cell' s mass is the cytoplasm; i.e., all that is not cell surface or cell ... biosynthesis of the cell Thus, a cell that grows adding 0.1 unit of mass at each time interval would this continuously for one cell cycle At the instant of division the two daughter cells together...

Ngày tải lên: 13/08/2014, 23:20

... Asymmetries in cell division Cell division is the process that one cell becomes two cells If the two daughter cells from a division are identical, this cell division is called symmetric division In ... two identical daughter cells; the other is asymmetric division, where the two daughter cells are different in size, protein contents and developmental fate Asymmetric cell division not only provides ... in cell division 1.3 Neuroblasts in Drosophila neurogenesis 1.4 Asymmetric cell division in Drosophila neuroblasts 1.4.1 Cell polarity setting up 1.4.2 Mitotic spindle orientation 12 1.4.3 Asymmetric...

Ngày tải lên: 10/09/2015, 15:49