pyrazolo 1 5 a 1 3 5 triazines from pyrazole scaffold

... of pyrazolo[ 1, 5- a] [1, 3 ,5] triazines 34 1. 3 .1 Synthesis of pyrazolo[ 1, 5- a] [1, 3 ,5] triazines from pyrazole scaffold 35 1. 3. 2 Synthesis of pyrazolo[ 1, 5- a] [1, 3 ,5] triazines from 1, 3 ,5- triazine ... 7-oxo-4-thioxopyrazolo [1, 5- a] [1, 3 ,5] triazines 43 13 Pyrazolo[ 1, 5- a] [1, 3 ,5] triazine scaffold generated by transformation of the 1, 3 ,5- thiadiazine ring 44 14 Pyrazolo[ 1, 5- a] [1, 3 ,5] triazine scaffold generated by transformation ... synthesis of pyrazolo[ 1, 5- a] [1, 3 ,5] triazines can be categorized into: annulation of the 1, 3 ,5- triazine ring onto a pyrazole scaffold; annulation of the pyrazole ring onto a 1, 3 ,5- triazine scaffold; ...

Ngày tải lên: 10/09/2015, 09:12

... exo -1, 3- b-glucanase Substrate (Gn) Km (mM ) 10 3: Vmax (mmol:min 21: mg 21) 10 3: (Vmax/Km) (min 21 : mg 21) ln (Vmax/Km) G3G G3G3G G3G3G3G G3G3G3G3G G3G3G3G3G3G 16 .5 5.0 1. 9 2.0 2 .1 0 .36 5. 5 14 16 18 ... chromatography 10 00 50 50 25 250 12 5 70 15 630 57 0 440 3 15 2 83 252 2 .5 4.6 6 .3 21 47 63 1. 8 2 .5 8.4 18 .8 25. 2 10 0 90 70 50 45 40 612 6 A A Kulminskaya et al (Eur J Biochem 268) q FEBS 20 01 General properties ... the EXG1 gene from the yeast Yarrowia lipolitica Yeast 15 , 16 31 16 44 Nakajima, T., Maitra, S.K & Ballou, C.E (19 76) An endoa1 !6-D -mannanase from a soil bacterium Purification, properties, and mode...

Ngày tải lên: 24/03/2014, 04:21

... Ineas for unknown reasons, was only discovered in 19 11 11 The Inca Empire fell very qui ckly after the death of their great ruler Huayna Capac in 15 25 Two of his sons, Atahualpa and Huascar, quarreled ... next Sapa Inca They fought against each other in a war and finally, in 15 32 , Atahualpa won During the war, news came that strange people had arrived on the coast These visitors, the Spaniards, ... 18 71, the samurai class was abolished a brought to an end c given special advantages b given high honors d created agai n 10 Japan became a modern, industrialized country a having a lot of farms...

Ngày tải lên: 15/10/2013, 17:42

... Ineas for unknown reasons, was only discovered in 19 11 11 The Inca Empire fell very qui ckly after the death of their great ruler Huayna Capac in 15 25 Two of his sons, Atahualpa and Huascar, quarreled ... next Sapa Inca They fought against each other in a war and finally, in 15 32 , Atahualpa won During the war, news came that strange people had arrived on the coast These visitors, the Spaniards, ... 18 71, the samurai class was abolished a brought to an end c given special advantages b given high honors d created agai n 10 Japan became a modern, industrialized country a having a lot of farms...

Ngày tải lên: 15/09/2015, 16:45

... thầy Bài 1: Tính 49 27 ì2 ì4 57 ì6 Hoạt động trò 18 5 64 3 - GV nhận xét, ch a * Củng cố cách tính Bài 2: (GV lu ý HS không làm cột c) a) 38 x b) 53 x 27 x 45 x - GV nhận xét, ch a * Củng cố ... 12 kẹo ta làm nh nào? - HSTL: Lấy 12 kẹo chia thành phần nhau: 12 : = (cái kẹo) Mỗi phần (3 b.Thực hành: Bài 1: kẹo) số kẹo) - GV hớng dẫn HS làm miệng ý a - HS nêu yêu cầu - HS làm miệng ý a ... nói: chia đợc 1, viết lên bảng: : =1 - GV vào phép nhân phép chia bảng gọi HS đọc + Cho HS lấy hai b a (mỗi b a có chấm tròn) ? lấy lần mấy? - GV viết lên bảng: x = 12 - GVchỉ vào b a, có chấm...

Ngày tải lên: 19/09/2013, 14:10

... 68.9( 8a) 29 .5( 4a) , 29 .5( 3) 16 .8(6, 7) 15 .5( 5, 7), 45. 2(7) 11 .2(8), 56 .8(6, 8) 65. 8(7) 19 .6(4b), 63. 3(4b, 9) 60.2( 4a, 1) 56 .4( 8a) 1. 5 6.2d 1. 5 1. 4 7.2 6.0 1. 9 1. 6 1. 2 1. 1 1. 2 1. 2 1. 3 1. 0 1. 2 1. 1 1. 1 ... Chemical shifts (p.p.m.) d13C d1H JHH 6 .17 (d) 2.2(4) 6. 41( d) 2.2(2) 7 .16 (d) 8.9(7) 6 .56 (d) 8.8(6) 4a 4b 16 4. 35 99. 35 16 8. 05 15 9 .36 14 5 .16 95. 49 13 8 .33 12 4.68 8a 8b 11 0.48 15 4 .37 10 8. 71 102. 81 1 85. 80 ... 67.0(4b), 55 .5( 9) 63 .5( 4a ,1) 55 .7( 8a) [1- C]Glucose [carboxy - 13 C]Shikimate % 13 Cb % 13 C13Cc % 13 Cb % 13 Cb 4.6 4.2 4 .3 4 .5 4.7 4.0 4 .3 4.6 28.9(2), 29.9(8b) 31 . 1 (1) , 28.8 (3) 55 .8(4, 2) 28 .3( 4), 31 . 2(8b)...

Ngày tải lên: 08/03/2014, 02:21

... ( A1 .3 .5. 7 ) A3 .) Practice with a partner: A3 .Practice with a partner: (a) What is this ? It’s a bank A3 .Practice with a partner: (a) What is this ? It’s a post office A3 .Practice with a partner: ... partner: (a) post office A3 .Practice with a partner: (a) supermarket A3 .Practice with a partner: (a) What is this ? Khách Sạn hotel A3 .Practice with a partner: (a) restaurant A3 .Practice with a partner: ... partner: (b) restaurant A3 .Practice with a partner: (b) hospital A3 .Practice with a partner: (b) trees A3 .Practice with a partner: (b) a lake A3 .Practice with a partner: (b) a mountain UNIT 7:...

Ngày tải lên: 18/07/2014, 02:00

... tra cũ: SIMON SAYS Thursday,Noverber 3rd, 2 011 Unit 5: My school A: 1, 2, Thursday,Noverber 3rd, 2 011 Unit 5: My school A: 1, 2, 1. Look, listen and repeat Thursday,Noverber 3rd, 2 011 Unit 5: ... 1. Look, listen and repeat 2.Look and say 3. Let’s talk This is _ Thursday,Noverber 3rd, 2 011 Unit 5: My school A: 1, 2, 1. Look, listen and repeat 2.Look and say 3. Let’s talk * Sumarize This is ... library: th­ viÖn tr­êng Thursday,Noverber 3rd, 2 011 Unit 5: My school A: 1, 2, 1. Look, listen and repeat This is my school This is my classroom And this is my school library Thursday,Noverber 3rd,...

Ngày tải lên: 29/10/2014, 10:00

... Friday,April 1st 2 011 UNIT 11 : PLACES OF INTEREST CHECK NEWWORDS: SECTION A 1, 2 ,3 *WHAT AND WHERE * It sounds nice amusement park national park swimming pool 4 Friday,April 1st 2 011 UNIT 11 : PLACES ... A 1, 2 ,3 *WHAT AND WHERE * It sounds nice amusement park national park swimming pool 3 4 Friday,April 1st 2 011 UNIT 11 : PLACES OF INTEREST SECTION A 1, 2 ,3 Look, listen and repeat Nam : Where are ... WARM UP : KIM’S GAME Friday,April st 2 011 UNIT 11 : A1 PLACES OF INTEREST SECTION A 1, 2 ,3 LOOK,LISTEN AND REPEAT Let’ s talk Let’s talk Listen and repeat LOOK AND SAY talk Let’s A2 LET’S TALK...

Ngày tải lên: 26/05/2015, 16:00

... (NAD+) activity 1ta8, 3bac, 3ba9, 3bab 3 .11 4 0. 31 3 .11 2 0 .34 3 3. 06 0 .36 4 13 14 17 Involved in nucleic acid binding 18 17 2 Ribonuclease 1goy, 1rpf, 1w4q, 3dgy, 1s9g, 1rca, 1i0v,1rga, 2rok, 1rds, ... thymidylate synthase (1f28 )16 9 S CH3 HN - 0 .56 67 H2N 0 .58 33 0 .5 714 0 .57 75 0 .56 0. 610 2 0 .59 32 0 . 53 85 0 .5 31 3 N Nolatrexed (thymitaq) O H N N 0.6 034 0 .54 68 0 .56 45 0.6 0 .58 57 0.6027 0 .57 53 N N H2C 0 .59 32 ... trans port and metabolism 1tls, 1ju6, 1qzf, 3k2h, 3jsu, 3cl9, 2aaz, 2blc, 3. 4 05 0. 63 16 17 15 8 3cd0, 3cd5, 3ccw, 3cdb 1j3j, 1tvv, 1hvy, 3nrr, 1tlc, 1f28, 1sej, 1tsd, 1o26, 2cfa, 3fnn, 3gwc 23 24 Dihydroorotate...

Ngày tải lên: 10/09/2015, 15:49

... 7.0±0.9 15 2e 4-BrC6H4 2.0±0 .5 14 .7 1. 3 15 2f 4-CF3C6H4 2.0 1. 9 15 .0 1. 7 15 2g 4-CNC6H4 13 .0±4.0 2.0±0.7 15 2h 2-Furyl 16 .0 1. 5 11 .1 0.9 15 2i 2-Thienyl 9.0 1. 5 10 .1 0.9 15 2j 2-Pyridyl 6.0±0 .5 11 .7±0.4 ... (%) at 10 0µM Compounds R A5 49 MDA-MB2 31 151 a C6H5 3. 6±0 .5 Not active 15 1b 4-MeC6H4 18 .8±0.2 Not active 15 1c 4-MeOC6H4 11 .9±0.7 Not active 15 1d 4-ClC6H4 2.7±0.4 Not active 15 1e 4-CF3C6H4 2 .5 0.2 ... N1(B) N3 (A) N9(C) 28.28 0.00 2.88 3. 45 27. 21 2 .30 0.00 3. 65 24 .11 0.00 3. 28 2. 83 24. 25 1. 80 0.00 3 .58 23. 37 0.00 5. 02 4 . 15 30 .09 3. 47 4.24 0.00 4.24 31 1 G** B3LYP/6 - 31 1 G** MP2/6 31 1 G** # A basis...

Ngày tải lên: 10/09/2015, 15:49

... trởng a dạng hoá doanh nghiệp: 3 .1 a dạng hoá đồng tâm ( a dạng hoá liên quan - Related diversification) 43 Là việc thêm vào sản phẩm dịch vụ nhng có liên hệ với hoạt động kinh doanh doanh nghiệp ... Có Không Có Không Thực s a đổi Thực s a đổi Thực s a đổi Thực s a đổi Thực s a đổi 11 Không Không Không Có Có Không Có Không Có Thực s a đổi Thực s a đổi Tiếp tục CL 3. 3 Điều chỉnh chiến lợc Việc ... điểm giáo s Michael Porter thuộc trờng kinh doanh Havard Mỹ - Ngời đợc mệnh danh cha đẻ chiến lợc cạnh tranh Trong Chiến lợc cạnh tranh xuất năm 19 85 ông khái niệm chiến lợc nh sau: Chiến lợc nghệ...

Ngày tải lên: 16/09/2013, 12:30

Ngày tải lên: 30/10/2013, 21:11

... câu 1- > câu 10 di õy: Cõu 1: (0 ,5 im): Nớc văn Lang đời vào thời gian: ý đúng: Khoanh vào (a) Khoảng 700 năm trớc Công nguyên(TCN) Cõu 2: (0 ,5 im) Thi nh Lý nc ta c i tờn l gỡ ? ý đúng: Khoanh ... (b) Nc u l c ; Cõu 3: (0 ,5 im) Cuc ngha hai Bà Trng din nm no ? ý đúng: Khoanh vào (b) Nm 40 Cõu 4: (0 ,5 im) Nh Lý ri ụ Thng Long vo nm ? ý đúng: Khoanh vào (b) Năm 10 10 Cõu 5: (1, 0 im) Nhà Lí dời ... t ln ca nc ta? Hết trờng tiểu học ngọc minh hớng dẫn chấm đề kiểm tra cuối học kỳ i - lớp Mụn : Lch s & a lý Nm hc: 2 010 - 2 011 A Phn trc nghim ( im) Khoanh trũn...

Ngày tải lên: 31/10/2013, 08:11

... chia ht cho l: í ỳng: Khoanh v o (a) 10 53 Cõu 5( 0 ,5 im): Trong cỏc s : 3 0 53 ; 12 55 ; 12 03; 10 46 - S chia ht cho nhng khụng chia ht cho l: a 3 0 53 b 12 55 ; c 12 03 d 10 46 í ỳng: Khoanh v o (c) 12 03 ... c 0 ,5 im) t tớnh ri tớnh : a) 10 2624 + 58 34 7 b) 628 450 - 35 8 13 ; c) 11 5 x 34 d) 3 51 3 6 :18 Kt qu: a) 16 09 71; c) 3 910 Cõu 2(2 ,5 im): b) 59 2 637 d) 19 52 Gii bi toỏn: (HS cú th lm mt hai cỏch sau): ... (B) 30 056 Cõu 2(0 ,5 im): Trong cỏc s : 2 15 4; 3 450 ; 42 03; 35 0 2 - S va chia ht cho va chia ht cho l: í ỳng: Khoanh vo (b) .3 450 ; Cõu 3( 0 ,5 im): Trong cỏc s : 10 53 ; 14 51 ; 12 03; 10 64 - S va chia ht...

Ngày tải lên: 31/10/2013, 08:11

... Seenprachawong, 2002: “An Economic Valuation of Coastal Ecosystems in Phang Nga Bay, Thailand” Kevin J.Boyle, 20 03: “Chapter 5: Contingent Valuation in Practice” in A Primer on Nonmarket Valuation” Tri ... Khánh Nam Tr n Võ Hùng Sơn, 20 05: “Household Demand for Improved Water Services in Ho Chi Minh City: A Comparison of Contingent Valuation and Choice Modelling Estimates” Udomsak Seenprachawong, ... http://www.congan.com.vn/?mod=detnews&catid=707&p=&id= 2 15 996 Đ Bá (2009, June 26) TPHCM: Th a “lô c t”, thi u nhà v sinh công c ng Đư c l y v t : http://giadinh.net.vn/200906260 83 057 588p0c1000/tp-hcm-thua-locot-thieu-nha-ve-sinh-cong-cong.htm...

Ngày tải lên: 26/12/2013, 15:29

... Interface #2 Interface #1 Interface #2 #5 800 (806) Ethernet (E0) Ethernet (E1) 16 00 Ethernet (E0) Ethernet (E1) Serial (S0) Serial (S1) 17 00 FastEthernet (FA0) FastEthernet (FA1) Serial (S0) Serial ... performed 4 -5 CCNA 2: Routers and Routing Basics v 3. 0 - Lab 5 .1. 3 Copyright  20 03, Cisco Systems, Inc Router Interface Summary Router Ethernet Ethernet Serial Serial Interface Model Interface #1 Interface ... Serial (S1) 250 0 Ethernet (E0) Ethernet (E1) Serial (S0) Serial (S1) 2600 FastEthernet 0/0 FastEthernet 0 /1 (FA0 /1) Serial 0/0 (S0/0) Serial 0 /1 (FA0/0) (S0 /1) In order to find out exactly how...

Ngày tải lên: 18/01/2014, 04:20

... Interface #2 Interface #1 Interface #2 #5 800 (806) Ethernet (E0) Ethernet (E1) 16 00 Ethernet (E0) Ethernet (E1) Serial (S0) Serial (S1) 17 00 FastEthernet (FA0) FastEthernet (FA1) Serial (S0) Serial ... performed 4 -5 CCNA 2: Routers and Routing Basics v 3. 0 - Lab 5 .1. 3 Copyright  20 03, Cisco Systems, Inc Router Interface Summary Router Ethernet Ethernet Serial Serial Interface Model Interface #1 Interface ... Serial (S1) 250 0 Ethernet (E0) Ethernet (E1) Serial (S0) Serial (S1) 2600 FastEthernet 0/0 FastEthernet 0 /1 (FA0 /1) Serial 0/0 (S0/0) Serial 0 /1 (FA0/0) (S0 /1) In order to find out exactly how...

Ngày tải lên: 18/01/2014, 04:20

... using a CAT straightthrough patch cable Locate a patch cable that is long enough to reach from the router to the hub Be sure to examine the cable ends carefully and select only straight through cables ... the workstation Ethernet cabling a The computer(s) will also connect to the hub using a straight-through patch cable Run CAT patch cables from each PC to where the switch or hub is located Connect ... the computer connections, insure that the link light on the NIC and the hub interface are both lit CCNA 1: Networking Basics v 3. 0 - Lab 5 .1. 3 Copyright  20 03, Cisco Systems, Inc ...

Ngày tải lên: 24/01/2014, 19:20