nonalcoholic fatty liver disease a pathological view
Báo cáo khoa học: Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice pot
... resistance and other metabolic abnormalities [12,13] Nonalcoholic fatty liver disease (NAFLD) is a spectrum of metabolic abnormalities ranging from simple accumulation of triglycerides in the liver ... containing a targeted replacement of the mouse apoE gene for the human apoE3 gene), we have shown that, in addition to its role in the maintenance of plasma lipid homeostasis, apoE plays a central ... photographs were taken at an original magnification of ·20 FEBS Journal 278 (2011) 3119–3129 ª 2011 The Authors Journal compilation ª 2011 FEBS E A Karavia et al Apolipoprotein E and diet-induced NAFLD...
- 11
- 544
- 0
Trends in Nonalcoholic Fatty Liver Disease–related Hospitalizations in US Children, Adolescents, and Young Adults pot
... fatty liver disease Hepatology 2005;42:473–80 Targher G, Arcaro G Non-alcoholic fatty liver disease and increased risk of cardiovascular disease Atherosclerosis 2007; 191:235–40 Pacifico L, Cantisani ... pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease Aliment Pharmacol Ther 2008;28:13–24 Schreuder TC, Verwer BJ, van Nieuwkerk CM, et al Nonalcoholic fatty liver disease: ... Angulo P Nonalcoholic fatty liver disease N Engl J Med 2002; 346:1221–31 Villanova N, Moscatiello S, Ramilli S, et al Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty...
- 7
- 421
- 0
Nonalcoholic fatty liver disease in children living in the obeseogenic society doc
... utility of radiological imaging in nonalcoholic fatty liver disease Gastroenterology 2002;123:745-750 Omagari K, Kadokawa Y, Masuda J, Egawa I, Sawa T, Hazama H, et al Fatty liver in non-alcoholic ... normal aminotransferases not exclude the presence of advanced disease. [16] Serum alkaline phosphatase and gamma-glutamyl transpeptidase may also be mildly abnormal Albumin, bilirubin, and platelet ... National Health and Nutrition Examination Survey JAMA 2002;287:356-359 26 Hamaguchi M, Kojima T, Takeda N, Nakagawa T, Taniguchi H, Fujii K, et al The metabolic syndrome as a predictor of nonalcoholic...
- 10
- 316
- 0
Báo cáo y học: " Hepatoprotective effects of Spirulina maxima in patients with non-alcoholic fatty liver disease: a case series" ppsx
... (A) Abdominal ultrasonography of a patient with nonalcoholic fatty liver disease (B) After a daily administration of Spirulina maxima, a normal liver parenchymal texture could be observed on an ... Spirulina maxima decreases serum aspartate aminotransferase, liver triacylglycerols (TAG) and total cholesterol (TC) This same pattern was observed in liver free fatty acids (with an important decrease ... non-alcoholic fatty liver disease detected by abdominal ultrasonography An increased hepatic parenchymal echotexture by fat infiltration could be appreciated ("brilliant liver" ) (B) The same patient after...
- 5
- 404
- 0
Milk thistle for treatment of nonalcoholic fatty liver disease
... 32 Hajaghamohammadi AA, Ziaee A, Rafiei R The Efficacy of Silymarin in Decreasing Transaminase Activities in Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Clinical Trial Hepat Mon ... References Ar ch ive of Angulo P Nonalcoholic fatty liver disease N Engl J Med 2002;346(16):1221-31 Vuppalanchi R, Chalasani N Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: ... Selected practical issues in their evaluation and management Hepatology 2009;49(1):306-17 Sanyal AJ AGA technical review on nonalcoholic fatty liver disease Gastroenterology 2002;123(5):1705-25 Marchesini...
- 5
- 303
- 0
The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years pptx
... liver transplantation in a 13-yr-old boy Pediatr Transplant 2007;11:796–8 Adams LA, Feldstein A, Lindor KD, et al Nonalcoholic fatty liver disease among patients with hypothalamic and pituitary ... requiring liver transplantation at 25 years of age She was found with macrovesicular steatosis on protocol liver biopsy as early as 14 days after liver transplantation, with well-established NASH at ... follow-up of patients with NAFLD and elevated liver enzymes Hepatology 2006;44:865–73 Adams LA, Lymp JF, St Sauver J, et al The natural history of nonalcoholic fatty liver disease: a population-based...
- 7
- 487
- 0
Fatty Liver Disease: NASH and Related Disorders ppt
... El-Hassan AY, Ibrahim EM, Al-Mulhim FA, Nabhan AA, Chammas MY Fatty infiltration of the liver: analysis of prevalence, radiological and clinical feature and influence on patient management Br J Radiol ... Standardized mortality of liver disease in type diabetes greatly exceeds vascular disease NASH recurs after liver transplantation Hepatic steatosis as a cause of primary graft non-function after ... importance of alcohol A key definitional issue is potential overlap between ‘primary’ (metabolic) NAFLD/NASH and pathologically similar fatty liver diseases associated with a single causative factor...
- 334
- 451
- 0
Obesity and Air Pollution: Global Risk Factors for Pediatric Non-alco- holic Fatty Liver Disease potx
... Mohammad-Alizadeh AH, Esna-Ashari F, Ardalan G, Hajarizadeh B Non-alcoholic fatty liver disease prevalence among school-aged children and adolescents in Iran and its association with biochemical and ... clinicopathological study Hepatology 2009;50(4):1113-20 47 Caserta CA, Pendino GM, Amante A, Vacalebre C, Fiorillo MT, Surace P, et al Cardiovascular risk factors, nonalcoholic fatty liver disease, and carotid ... with NAFLD The majority of children were aged 12-17 y and Mexican American All subjects were overweight Abbreviations: ALT, alanine aminotransferase; NAFLD; non-alcoholic fatty liver disease; NASH,...
- 9
- 552
- 0
Báo cáo khoa học: "Human vascular adhesion proteın-1 (VAP-1): Serum levels for hepatocellular carcinoma in non-alcoholic and alcoholic fatty liver disease" pdf
... disease The diagnosis of non-alcoholic fatty liver disease cirrhosis was made in patients who had clinical features and liver biopsies compatible with non-alcoholic fatty disease Females and males ... endothelial cell adhesion cascade We suggested that this protein may be a significant marker for HCC in patient with alcoholic and nonalcoholic fatty liver diseases Author details Department of General ... wells were always measured after a 3-min incubation time Each sample was measured in triplicate with both the anti-VAP-1 mAb and the negative control mAb The specific VAP-1 value was calculated by...
- 4
- 294
- 0
Báo cáo y học: " Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein" doc
... marker of alcoholinduced fatty liver in a rodent model, which may help diagnose early alcohol-induced pathophysiological alterations in clinical practice Materials and methods Animal model and ... http://www.jbiomedsci.com/content/18/1/52 Page of 10 Figure Histological analysis and comparisons among four groups of rats Images of livers from normal control, rats with alcoholic fatty liver (AFL), non-alcoholic fatty liver (NAFL, ... a candidate biomarker of AFL, and Hp is a reliable biomarker that decrease in NASH and liver fibrosis In particular, serum CRP may be qualified to be an elevated surveillance target for early...
- 10
- 486
- 0
Fatty Liver Disease : Nash and Related Disorders - part 1 ppt
... importance of alcohol A key definitional issue is potential overlap between ‘primary’ (metabolic) NAFLD/NASH and pathologically similar fatty liver diseases associated with a single causative factor ... Standardized mortality of liver disease in type diabetes greatly exceeds vascular disease NASH recurs after liver transplantation Hepatic steatosis as a cause of primary graft non-function after ... definitional and semantic issues, spectrum and general importance of non-alcoholic fatty liver diseases (NAFLD) Nonalcoholic steatohepatitis (NASH) is a form of metabolic liver disease in which fatty...
- 32
- 213
- 0
Fatty Liver Disease : Nash and Related Disorders - part 3 potx
... et al Non-alcoholic fatty liver disease: a feature of the metabolic syndrome Diabetes 2001; 50: 1844–50 15 Sanyal AJ, Campbell-Sargent C, Mirshahi F et al Nonalcoholic steatohepatitis: association ... ballooned hepatocytes and no or very mild inflammation; grey area, ballooning of hepatocytes and mild to moderate portal inflammation; black area, intra-acinar and portal inflammation The significance of ... in an increased free fatty acid (FFA) load that is delivered to the liver The liver adapts by increased mitochondrial fatty acid β-oxidation, re-esterification of fatty acids to triglycerides and...
- 34
- 342
- 0
Fatty Liver Disease : Nash and Related Disorders - part 4 pot
... serves as a sensor of increased intracellular FFA in the hepatocyte It is activated principally by unsaturated and polyunsaturated fatty acids Activated PPARα forms a heterodimeric transactivating ... appear to arise not as a result of a genotoxic effect of accumulated fatty acids and fatty acid derivatives, but as direct result of chronic PPARα activation stimulation by the accumulated fatty ... increase substantially as a result of the accumulation of fatty acyl activators of PPARα Increased cytotoxicity from the accumulation of conventional long-chain fatty acids and, to a greater...
- 34
- 264
- 0
Fatty Liver Disease : Nash and Related Disorders - part 5 pdf
... On laboratory evaluation, patients usually have mild elevations in their aminotransferase levels, with an alanine aminotransferase (ALT) predominance Occasionally, the alkaline phosphatase may ... peroxisomal β-oxidation of fatty acids As a consequence of its absence, long-chain fatty acids accumulate in the liver In mice lacking acyl-CoA oxidase, DNA synthesis and mitotic index after partial ... obesity and hyperleptinaemia are therefore mandatory to address the leptin paradox, and to exploit it therapeutically PPARα and γ expression and signalling PPARs are a family of ligand-activated transcription...
- 34
- 383
- 0
Fatty Liver Disease : Nash and Related Disorders - part 6 docx
... Physical examination Clinical stigmata of chronic liver disease such as the characteristic peripheral muscle wasting, gynaecomastia, spider telangiectasias or caput medusa are rarely seen on initial ... and physical examination Repeat liver enzymes Elevated ALT or AST Normal ALT or AST Consider Imaging Non-invasive assessment of advanced fibrosis No fatty liver Fatty liver No evidence of advanced ... report, the data set was evaluated in 15 676 subjects aged 17 years and older and the prevalence of AT elevation (men: aspartate aminotransferase (AST) > 37 IU/L, alanine aminotransferase (ALT) > 40...
- 34
- 353
- 0
Fatty Liver Disease : Nash and Related Disorders - part 7 ppsx
... before and after liver transplantion Abstract Non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH)aa severe form of NAFLDahas produced an ironic combination of adverse ... Sekikawa A, Tominaga M, Takahashi K et al Prevalence of diabetes and impaired glucose tolerance in Funagata area, Japan Diabetes Care 1993; 16: 570–4 Zimmet P, Alberti KG, Shaw J Global and societal ... aminotransferase; AST, serum aspartate aminotransferase; NASH, non-alcoholic steatohepatitis; NAFLD, non-alcoholic fatty liver disease [52] This interaction is particularly relevant to a region with a massive...
- 34
- 289
- 0
Fatty Liver Disease : Nash and Related Disorders - part 8 potx
... Lipoatrophic diabetes and end-stage liver disease secondary to nonalcoholic steatohepatitis with recurrence after liver transplantation Transplantation 2001; 71: 892–5 48 Garg A, Misra A Hepatic steatosis, ... a- β-proteinaemia can be alleviated by dietary control of fat intake, particularly saturated fats, and supplementation with vitamins A, K and E Vitamins K and E can easily be replaced through oral consumption ... not a primary cause of fatty liver disease, it only masquerades as NAFLD Treatment for Wilson’s disease is not directed against hepatic steatosis, it involves copper chelation, or liver transplantation...
- 34
- 454
- 0
Fatty Liver Disease : Nash and Related Disorders - part 10 pdf
... nonalcoholic fatty liver disease: prevalence and correlates Dig Dis Sci 2003; 48: 2173–81 Adams LA, Feldstein A, Lindor KD, Angulo P Nonalcoholic fatty liver disease among patients with hypothalamic and ... aminotransferases see alanine aminotransferase (ALT); aspartate aminotransferase (AST) amiodarone animal models 95 NAFLD/NASH in children 230–231 steatosis 257 amphiphilic drugs, animal models 95–96 animal models ... of fatty liver: risk of chronic liver disease and death Gut 2004; 53: 750–5 53 Harrison SA, Torgerson S, Hayashi PH The natural history of non-alcoholic fatty liver disease: a clinical histopathological...
- 27
- 313
- 0
báo cáo khoa học: "Hepatic cerebrospinal fluid pseudocyst mimicking hydatid liver disease: a case report" doc
... epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern Clin Microbiol Rev 2004, 17:107-135 El-Shazly AM, Saad RM, Belal US, Sakr T, Zakae HA: Evaluation of ELISA and IHAT ... http://www.jmedicalcasereports.com/content/5/1/475 abdomen provides a more accurate diagnosis [18] For the diagnosis of an extra-axially growing hepatic pseudocyst, abdominal CT images are typical The pseudocyst is surrounded by an annulus ... ventriculoperitoneal shunts: case report and review of the literature Pediatr Neurosurg 2007, 43:501-503 Pathi R, Sage M, Slavotinek J, Hanieh A: Abdominal cerebrospinal fluid pseudocyst Case report Australas...
- 3
- 399
- 0
Báo cáo y học: "Elevated endotoxin levels in non-alcoholic fatty liver disease" potx
... recognised that insulin resistant states, such as T2DM, cardiovascular disease and the metabolic syndrome, are characterised by a low-grade systemic inflammation, as well as inflammatory changes in adipose ... for the statistical analysis and interpretation of data; EA, MSA HMS and AIA for their interpretation of data and intellectual input; ADB for the acquisition and interpretation of data; SK for ... the median of the data Statistical analysis compared the log mean serum levels of the inflammatory markers at each fibrosis stage of liver disease against the log mean serum levels of healthy controls...
- 10
- 364
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25