... (81) PB and EvN developed the data normalization procedure, the noise model, and the hierarchical clustering procedure, and applied these to the human and mouse CAGE data PC and JK produced the CAGE ... ChIP-seq with Solexa sequencing, there will similarly be processes such as the shearing or sonication of the DNA, adding of the linkers, and growing clusters on the surface of the flow cell With ... 0/1 hour and for the technical replicate Figure shows this theoretical distribution (in black) together with the observed histogram of z-values for the four replicates Although the data are noisy,...
Ngày tải lên: 14/08/2014, 21:20
... segments from the intersection of the regions associated to higher level hypotheses (from the father, semantic network node) and a shapefile provided by the user The output of the interpretation ... logical And or Or operations The Expression element enables the user to create named variables form the object hypotheses properties The values of those variables, are stored within the object hypotheses, ... attributes over the image segments that represent the object hypotheses, and to produce histograms and scatter plots from their values In the stepwise execution mode, the user can also undo the operations...
Ngày tải lên: 01/10/2015, 08:46
Tài liệu The Acquisition of Drugs and Biologics for Chemical and Biological Warfare Defense - Department of Defense Interactions with the Food and Drug Administration doc
... the National Defense Research Institute The latter is a federally funded research and development center sponsored by OSD, the Joint Staff, the unified commands, and the defense agencies in the ... recordkeeping, and acceptance by military personnel and the wider public—underline the importance of licensed drugs By contrast, the regulatory requirements of IND use, the burden of recordkeeping, and the ... fragmented within the department and between the government and private contractors DoD acquisition personnel and DoD contractors often lack the technical and managerial expertise and experience...
Ngày tải lên: 17/02/2014, 11:20
Báo cáo khoa học: BRCA1 16 years later: nuclear import and export processes doc
... had no inhibitory effect on the nuclear export of the mutant The authors concluded that BARD1 masks the amino terminal BRCA1 nuclear export sequence and, therefore, export could be regulated by ... demonstrated that the presence of a BRCA1 signal outside the nucleus could be the result BRCA1 nuclear import and export of experimental artifact Analysis of the antibodies for their utility in ... clearly demonstrate interaction with import machinery Chen et al [11] carried the work to the next step and demonstrated the interaction of NLS1 (amino acids 501–508) with importin alpha This clearly...
Ngày tải lên: 06/03/2014, 22:21
Digital Signal Processing and Applications with the C6713 and C6416 DSK (Topics in Digital Signal Processing) pot
... Installation and Support Use the USB cable to connect the DSK board to the USB port on the PC Use the 5-V power supply included with the DSK package to connect to the +5-V power connector on the DSK ... initializes the DSK, the AIC23 codec onboard the DSK, and the two McBSPs on the C6713 processor Within c6713dskinit.c, the function DSK6713_init initializes the BSL file, which must be called before the ... directly within the appropriate command windows In lieu of adding the three library files to the project by retrieving them from their specific locations, it is more convenient to add them within the...
Ngày tải lên: 15/03/2014, 17:20
Comparision metal analysis in sediments using EDXRF and ICP OES with the HCl and tessie extraction metho
... of bars in Figs and 3) The percentages described in the text correspond to the arithmetic averages of the months, with their respective standard deviations At first sight, in Figs and 3, it may ... Ni, Fe, and Co in the sediments, using the ICP-OES and EDXRF techniques, showed that the profiles obtained are very similar for the Mn, Zn, Cu, and Ni distributions The study indicated that the EDXRF ... lead, Fig 3C, which, in theoretical terms, should be the ion with the highest tendency to complex with the organic matter present in the water column In July/1999, August/1999, and January/2000 Pb...
Ngày tải lên: 15/03/2014, 23:22
Cancer Research UK’s strategy 2009–2014: Cancer Research UK’s aim is to reduce the number of deaths from cancer. Our future plans are ambitious, but they are in line with the challenge and the responsibility we face. docx
... survival and in preventing thousands of new cases of the disease, both in the UK and across the world Cancer Research UK has been at the heart of this progress thanks to the sustained support and ... progress and has saved the lives of hundreds of thousands of people in the UK and many millions more around the world • We were the first to discover the breast cancer susceptibility gene BRCA2 and ... provide the foundation for advances in the prevention, detection and treatment of cancer Surgery, radiotherapy and chemotherapy continue to be the most important approaches to treatment The discovery...
Ngày tải lên: 22/03/2014, 16:21
Báo cáo khoa học: Comparative proteomic analysis identifies proteins associated with the development and progression of colorectal carcinoma pot
... in the Mascot database (Table 1) The MSDB identification number, the theoretical molecular mass, the theoretical pI, the sequence coverage and the MASCOT score are shown in Table Among them, the ... S100A9 and LASP-1 may play an important role in the development and progression of CRC Further functional and clinical analysis of the proteins is necessary to elucidate their precise role in the ... from the Ethics Committee of Southern Medical University The informed consent with a uniform format was designed by the Ethics Committee and signed by the patients involved in the study before the...
Ngày tải lên: 23/03/2014, 03:20
List of non-governmental organizations in consultative status with the Economic and Social Council ppt
... Migration and Integration (2007) Foundation for Subjective Experiments and Research (2008) Foundation for the American Indian (2005) Foundation for the Child and the Family (2004) Foundation for the ... Centre for the Independence of the Judiciary and the Legal Profession (2000) Arab Council for Childhood and Development (1991) Arab Lawyers Union (1971) Arab Mexican Chamber of Industry and Commerce ... Roster by virtue of their consultative status with other United Nations bodies or the specialized agencies 87 Non-governmental organizations with outstanding quadrennial...
Ngày tải lên: 23/03/2014, 21:20
Interfacial Compatibility in Microelectronics : Moving Away from the Trial and Error Approach ppt
... Under thermal cycling, the solder interconnections experience strains and stresses due to the differences in CTE of the component packages and the PWBs In drop tests, on the other hand, strains and ... any information about the time frame of the changes and thus must be combined with the reaction kinetics If the necessary thermodynamic data of a system is combined with the available diffusion ... the relations between microstructures and the mechanical and physical properties of materials When the results obtained with the above described methods are further combined with mechanical data...
Ngày tải lên: 24/03/2014, 02:20
Behind with the Laundry and Living off Chocolate pdf
... Behind with the Laundry:Behind with the Laundry 8/12/06 15:45 Page Behind with the Laundry:Behind with the Laundry 8/12/06 15:45 Page Behind with the Laundry and Living off Chocolate ... Laundry:Behind with the Laundry 8/12/06 15:45 For Nick, Georgie and Barney Page Behind with the Laundry:Behind with the Laundry 8/12/06 15:45 Page Behind with the Laundry:Behind with the Laundry ... look after, they did just that, thought about themselves They made time for their friends, had nights out with the girls, painted their toenails and spent hours in the bath with their faces covered...
Ngày tải lên: 28/03/2014, 19:20
Providing Clinicians with the Skills and Tools to Assess, Prevent and Treat Pediatric Obesity pdf
... counseling and education, and incorporate the 2007 Expert Committee recommendations regarding the prevention, assessment and treatment of childhood and adolescent obesity The HOPE curriculum reviews the ... techniques to identify children and families at risk, the current evidence for health intervention recommendations, and teaches the theoretical rationale and art of constructive and culturally sensitive ... EPIDEMIOLOGY AND ETIOLOGY OF PEDIATRIC OBESITY To understand the epidemiology of childhood obesity in the US To review the underlying etiologies of childhood obesity EPIDEMIOLOGY AND ETIOLOGY To review the...
Ngày tải lên: 28/03/2014, 21:20
nuclear import and export in plants and animals - t. tzfira, vitaly citovsky
... Tzfira and Vitaly Citovsky Nuclear Import and Export in Plants and Animals Nuclear Import and Export in Plants and Animals MOLECULAR BIOLOGY INTELLIGENCE UNIT Nuclear Import and Export in Plants and ... faster than the movement of the filaments, on the other hand, it would slip unhindered through the sieve Where the translocating species can interact with the FG motif, on the other hand, short-lived ... (NLS) peptides associate with receptors of the importin/karyopherin family in the cytoplasm, and dissociate from them inside the nucleus The canonical import receptor is importin β,23 also known...
Ngày tải lên: 08/04/2014, 12:52
digital signal processing and applications with the c6713 and c6416 dsk
... Figure 2-11 Other than the data types shown in this figure, there are some other specific data types For example, the dynamic data type is always used for Express VIs, and the waveform data type, ... Value from the shortcut menu 23 Lab Label the second knob as Input and repeat all the adjustments as done for the first knob except for the data representation part The data type of the second ... demonstrate the difference in the outcome As the final step of configuring the FP, align and distribute the objects using the appropriate buttons on the FP toolbar To set the outputs, locate and place...
Ngày tải lên: 01/06/2014, 01:13
báo cáo hóa học:" Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer" pptx
... serum HMGB1 and CEA levels and evaluated the correlation of these values with the progression of gastric carcinogenesis We then estimated the validity of HMGB1 as a potential biomarker for the screening, ... from the greater curvature of the antrum and the midpoint of the greater curvature of the gastric body via endoscopic biopsy In the patients with cancer two specimens were obtained from the cancerous ... group), 40 with EGC (EGC group), 45 with AGC without distant metastasis (AGC group), and 42 with metastatic GC (M group) The clinical and pathological characteristics in each subject and their tumor...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke" pptx
... assess the strength of association between the low ficolin-3 and high CRP levels on the one hand and the unfavorable outcome of the disease on the other hand, we repeated the analysis as above in the ... secondary to the negative correlation between ficolin-3 on the one hand and the severity of ischemic stroke and the infarct size on the other hand, as discussed above It is well known that both the high ... indirect measure of the severity of the stroke, the concentration of the S100β in the follow up samples as an indicator of the infarct size, and the outcome of the disease assessed by the modified Rankin...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " Research Article A Hilbert-Type Linear Operator with the Norm and Its Applications" pdf
... ϕ and am , bn are defined as in Lemma 2.4 m On the other hand, from the strictly monotonic decrease of the function g u ln u/ u − and the exponents λ/r − ε/p − < 0, λ/s − ε/q − < and − α ≥ 0, and ... π/p , b ∈ q T a, b is the formal inner product of T a and b The inequalities 1.1 – 1.4 play important roles in theoretical analysis and applications These inequalities and their integral forms ... that 1.7 and 1.8 are two equivalent inequalities and their constant factors π/sin π/p and π/sin π/p 2p are the best possible When α 1, the expressions 1.7 and 1.8 can be reduced to 1.3 and 1.4...
Ngày tải lên: 22/06/2014, 02:20
Online Advertising Update:A Review of Research Data Measuring the Growth and Effectiveness docx
... is the new and exciting research regarding the Web and the affluent and senior management markets The data show that the more affluent and the more senior the manager, the more valuable the Web becomes ... alike is the increased adoption of broadband access Simply put: the faster pages load, the more people spend time online, the more they do, and the more they view The number of broadband households ... immediately click on it, and thereby take themselves away from the site to which they originally came Instead, they may remember the ad and its message, and later make a visit to the advertiser’s site...
Ngày tải lên: 28/06/2014, 18:20
Báo cáo khoa học: "Hydraulic conductance of root and shoot measured with the transient and dynamic modes of the high-pressure flowmete" ppsx
... with the transient mode (3 to consecutive measurements) and then with the dynamic mode except for the first batch of plants (1998) for which it was the opposite After the measurement of kr, the ... above the soil surface and kept until measurement covered by a plastic bag with the collar plunging in water Root systems were flooded in the pot without removing it from the substrate and connected ... According to the Ohm’s law analogue, the water status of a plant is controlled by the soil water availability and the hydraulic properties of the pathway used by the water flow from soil to the atmosphere...
Ngày tải lên: 08/08/2014, 14:21
Báo cáo y học: " Preliminary data concerning the reliability and psychometric properties of the Greek translation of the 20-item Subjective Well-Being Under Neuroleptic Treatment Scale (SWN-20)" pdf
... designed the study and participated in the analysis of the data, interpretation and writing of the manuscript MS, KM, EP, SM, IC, KA, AC and SD participated in the gathering of the data, interpretation ... QoL and SWB are assessed with the use of rating scales, some of them being self-report ones Although there are significant problems with definitions and with the reliability and validity of these ... calculated to assess the relationship of the SWN20 and its factors to the other psychometric tests Results The means and standard deviations for the scores for all scales are shown in Table The SWN-20...
Ngày tải lên: 08/08/2014, 23:21