... of Bag-1 Morpho/AS to JAR cells did not alter the expression of PTEN after the exposure to hypoxia, which would mean that the expression of PTEN, and also that of Bcl-X, was independent of ... development of various obstet- rical complications. Apoptosis is a cascade of events that involves ac- tivation of many genes and synthesis of various pro- teins. The importance of several apoptotic ... the expression of such positive and negative regulators of apoptosis would determine apoptotic propensity. In this study, we focused on the role of Bag-1 in the regulation of trophoblastic...
Ngày tải lên: 31/10/2012, 15:12
Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp
Ngày tải lên: 05/09/2013, 09:08
ISOTOPE HYDROGRAPH SEPARATION FOR MODELING OF RUNOFF MECHANISMS OF ATMOSPHERICALLY DERIVED CHEMICAL AND RADIOACTIVE POLLUTANTS
Ngày tải lên: 05/09/2013, 09:08
Mechanisms of Unstable Nitrite Inhibition of Aerobic Phosphate Uptake
Ngày tải lên: 05/09/2013, 09:38
Transmission mechanisms of monetary policy the evidence
... which raises the desire of consumers to hold durable goods or housing, thus ↑ spending on them. Expansionary monetary policy P e ↑, value of financial assets ↑, likelihood of financial distress ... Inc. 25 - 13 Transmission Mechanisms of Monetary Policy Traditional Interest-Rate Channels: expansionary monetary policy i r ↓, I ↑, Y↑ The interest rate channel of monetary transmission applies ... price for it relative to the cost of the facilities and equipment they are buying. I ↑ because firms can buy a lot of new investment goods with only a small issue of stock. The transmission mechanism...
Ngày tải lên: 05/01/2014, 17:01
Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
... referring to the mechanism of action of some FP methods. We did not state the mechanism of action of any FP methods and thus asked women to express their beliefs independently of their actual choices ... actual choices and independently of their perceptions of available choices. In our study, we also assessed women's understanding about the mechanisms of action of specific FP methods, and we ... hypothetical method of FP. In further sections women were asked about their knowl- edge of the mechanism of action of specific FP methods and if doctors or providers should explain the details of how a...
Ngày tải lên: 13/02/2014, 06:20
Tài liệu Báo cáo khoa học: Mechanisms of amyloid fibril formation – focus on domain-swapping doc
... only after partial unfold- ing of the a-helix from the body of the b-sheet (Fig. 2C). Possible role of domain-swapping in the ‘off-pathway folding’ (OFF) model The OFF model for amyloid formation ... our understanding of the importance of different parts of the molecule and their flexibility in the process of amy- loid fibril formation often results more from a struc- tural analysis of the amyloid ... domain-swapping. For some of the case proteins relevant to the focus of this review on domain-swapping, descriptions of the mechanisms are provided, whereas, for most of the other cases, the original...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Survival mechanisms of pathogenic Mycobacterium tuberculosis H37Rv ppt
... of ingested pathogen Release of digested material by exocytosis Fig. 1. Detailed structure of a macrophage showing a typical process of phagocytosis. Phagosome Lysosome Inhibition of fusion of ... pro- teins of mycobacteria have a profound influence on its pathogenicity. It was found that the disruption of an erp gene of M. tuberculosis encoding a secretory pro- tein effects the survival of M. ... candidates for the treatment of the disease. A variety of mechanisms have been suggested to con- tribute towards the survival of Mycobacterium within macrophages. These mechanisms are shown as a...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
... pathophysiological mechanisms of endothelial dysfunction and testosterone deficiency include penile vascular insufficiency as a result of the loss of nitric oxide synthase expression and activity and the loss of ... pathophysiological mechanisms of obesity-induced androgen deficiency and hypogonadism-induced obesity remain the subject of intense investigation. Several hypotheses have discussed the relationship of androgen ... organic ED, in which approximately 43% of men with MetS had ED and the severity of ED increased with the components of the MetS [84]. Interestingly, the severity of ED was positively associated with...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf
... (i.e. deprotonation of C2a-OH of HEThDP and proton- ation of FAD at N5 and N1). The tight and rigid binding of both cofactors excludes a direct carbanion mechanism with covalent linkage between C2a of the HEThDP ... channel of E1 such that (a) formation of 8-(S)-acetyl-dihydrolipoylamide is more likely than of the 6-S isomer and (b) protonation of the lipoamide dithiolane by His407 K. Tittmann Redox reactions of ... thiyl radical. An additional intricacy of this mechanism is the necessity of a structural rearrangement of CoA in the course of catalysis: initially, the reactive thiol group of CoA must be positioned proximal...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... ring opening of an epoxide inter- mediate at either of its two C-O bonds [219,220]. The sum of these findings strongly invokes the notion of oxygen activation during redox cycling of the diverse dioxygenases ... 760,69– 76. 164. Golly, I. & Hlavica, P. (1983) Mechanisms of extrahepatic bioactivation of aromatic amines: the r ole of he moglobin in the N-oxidation of 4-chloraniline. In Extr ahepatic Drug Me ... seems w orth mentioning that the rate of cumene hydroperoxide-induced loss of CO-reactive CYP2B4 [85] could be demonstrated to be far below that of release of N-oxy product from the ternary c omplex...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu AMAZONIAN ACCESSIONS OF WILD HEVEA GERMPLASM - A POTENTIAL SOURCE OF DROUGHT TOLERANCE pptx
... leaf structural characters of selected accessions of Hevea brasiliensis Transverse section of one year old twig of wild Hevea accession MT 1623 having maximum number of IXP IXP PX X 16 X 4 17 Clonal ... annual rain fall of 7.5mm per day - average of 90 rainy days/ year. 1 A mature rubber plantation Amazonian accessions of wild Hevea germplasm – A potential source of drought tolerance M. A. ... Thank you all 16 Accession/ Clone No. of primary xylem points (PXP) No. of intraxylary phloem points (IXP) Diameter of twig (mm) IXP/ mm diameter of twig MT 1623 104.50 77.00 15.60 4.94 MT...
Ngày tải lên: 21/02/2014, 04:20
Motivating Better Hygiene Behaviour: Importance for Public Health Mechanisms of Change doc
... the lighter forms of water contamination of their own water sources. Lack of water and soap for handwashing plays a bigger role in the transmission of diarrhoeal diseases than the drinking of unboiled water ... 4 . Motivating Better Hygiene Behaviour: Importance for Pubiic Health Mechanisms of Change Motivating Better Hygiene Behaviour: Importance for Public Health Mechanisms of Change Authors Christine van Wijk and Tineke Murre, IRC International Water ... it is necessary to choose the objec - tives and determine howtheir achievement will be measured before the programme starts and as the work progresses. The setting of measurable objectives and the monitoring of their realization is often a weak element: many hygiene education programmes focus only on developing and monitoring of inputs: the...
Ngày tải lên: 05/03/2014, 21:20
Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf
... inactive in the absence of salt [13]. Although the structures of the fragments of Mglu [10] and algal carbonic anhydr- ase [14] have been determined, the mechanism of salt tolerance is not very ... C-ter- minal domain of the N structure. Salt- tolerant mechanism A comparison between the structures of Mglu and salt- labile glutaminase was expected to elucidate the structural features of salt- tolerant ... residues; F, major fragment of Mglu; G, presence of L-glutamate; Mglu, Micrococcus glutaminase; PDB, protein data bank; N, absence of additives; T, presence of Tris; TG, presence of Tris + L-glutamate. 738...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death ppt
... amounts of nitric oxide (NO) generated by pathological expression of NO synthase isoforms are certainly neurotoxic, whereas homeostatic levels of NO produced by the endothelial isoform of this ... neuroprotective effects of CBs. CB receptor-independent mechanisms A number of potentially neuroprotective as well as neurotoxic effects of CBs do not appear to be medi- ated by direct activation of CB receptors. ... stimulation of glutamate receptors, particularly of the ionotropic [i.e. N-methyl-d-aspartate (NMDA)] subtype, which leads to the accumulation of toxic amounts of intracellular free calcium and of nitrogen...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Molecular mechanisms of the phospho-dependent prolyl cis ⁄ trans isomerase Pin1 docx
... spectrum of the triply phosphorylated SRSRpT 212 PpS 214 LPpT 217 PPTR peptide of Tau. The cis conformation for the Pro219 is below the limit of detection. Upon addition of a catalytic amount of Pin1, ... elucidation. Structural features of Pin1 substrates Concerning the function of Pin1, a first intriguing observation is that many of its substrates meet the cri- teria for the recently identified class of intrinsically unfolded ... molecular mechanisms of the enzyme action. Most importantly, we want to critically review the evidence that Pin1 would or would not act as a prolyl cis ⁄ trans isomerase. Molecular mechanisms of Pin1...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Two L-amino acid oxidase isoenzymes from Russell’s viper (Daboia russelli russelli) venom with different mechanisms of inhibition by substrate analogs pdf
... Characterization of flavin cofactor. (A) UV–visible absorption spectrum between 300 and 600 nm of enzyme-bound cofactor of: (1) the sample obtained from gel filtration chromatography; (2) cofactor separated ... the enzymes. Identification of cofactor The absorption spectra between 300 and 600 nm of holo-LAAO from the active fractions of Sephadex G- 100 chromatography containing a mixture of L 1 and L 2 , the isolated cofactor ... similar to those of FAD. The shifting of absorp- tion maxima of the enzyme-bound flavin was due to its microenvironment. The RP-HPLC profiles of the cofactor dissociated by heat and of reference FAD...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Mechanisms of accumulation of arachidonate in phosphatidylinositol in yellowtail A comparative study of acylation systems of phospholipids in rat and the fish species Seriola quinqueradiata pot
... Mechanisms of accumulation of arachidonate in phosphatidylinositol in yellowtail A comparative study of acylation systems of phospholipids in rat and the fish species Seriola ... is composed mainly of 1-stearoyl-2-arachidonoyl species also applies to tissues of yellowtail. Accumulation of arachidonic acid in PtdIns in the presence of the large amounts of docosahexaenoic ... concentration of 50 l M , the level of acylation of docosahexaenoic acid to lysoPtdIns was 19.4 nmol per 10 min per mg protein, which was about one-fifth of that obtained with the same con- centration of...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Kinetic mechanisms of glycine oxidase fromBacillus subtilis docx
Ngày tải lên: 08/03/2014, 08:20
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