joints and de grees of free dom

... segment types are of importance: Start Of Frame (SOF), De ne Human Table (DHT), De ne Quantiza- tion Table (DQT), and Start Of Scan (SOS (quite appropriate)). Here are some type de nitions that describe ... k'>=64 then ]] else acdecode t k' ] ] Both the function dcdecode and the function acdecode will be used in subsection 5.1. The names `dc' and `ac' are used frequently ... modern, polymorphically typed and lazily evaluated languages like Haskell HuFa92], Gofer Jone94] and Clean PlEe95]. We will prove this by giving an implementation of a JPEG decoder in the Gofer...

Ngày tải lên: 09/12/2013, 15:15

Ngày tải lên: 14/12/2013, 00:41

Ngày tải lên: 21/01/2014, 09:20

... characterization of numerous com- plexes of the human HPRT and several bacterial and protozoan HPRTs have been undertaken [13–17]. The structure of human HPRT can be divided into two domains: a core domain and ... loops left unmodeled. The 3D structures of HPRTs have been divided into a core and a hood domain [14]. The core domain of PRTFDC1 contains a six-stranded twisted parallel b-sheet surrounded by three ... elucidation of the structure of PRTFDC1 and the de nition of its ligand binding specificity from a large metabolome library provides an initial start point for de ning the molecular function of PRTFDC1....

Ngày tải lên: 15/02/2014, 01:20

... Model and simulations of cytochrome c reduction by NOS enzymes. (A) Scheme of cytochrome c reduction. The model uses four kinetic rates: dissociation (k 1 ) and association (k 2 ) of the FMN and ... states (NADPH -free ⁄ CaM -free, NADPH-bound ⁄ CaM -free and CaM-bound) [59]. Subsequent measures made with CT point mutants of nNOS (R1400E, R1400S or F1395S) [60,61], and nNOS mutants possessing graded CT ... activity and FMN deshielding. The figure plots relative cytochrome c reduc- tase activities of various CaM -free nNOS flavoproteins and CaM- bound wild-type versus their degree of FMN deshielding....

Ngày tải lên: 18/02/2014, 11:20

... 5.4 and 5.8), Tris ⁄ HCl (pH 6.5, 7.0, 7.5 and 8.0) and glycine ⁄ NaOH (pH 8.6, 9.0 and 9.6). (B) Dependence of Rep245 polymerase activity on metal ions. The results are the means of three independent ... Rep245 was capable of utilizing both ribonucleotides and deoxyribonucleotides for de novo primer synthesis and it synthesized DNA products up to several kb in length in a template-dependent manner. ... recommended cut-off of 6) and the secondary structure profile (data not shown), both of which point to considerable fold similarity. To build the Rep245 model, we performed 16 pairwise and multiple alignments...

Ngày tải lên: 18/02/2014, 18:20

... of LN and LE (circles) modules, domain IV, and a coiled-coil (cc) domain II,I. Fig. 2. SDS/PAGE of puri®ed recombinant fragments c ontaining domain IV of b1orb2 chain under nonreducing (A) and ... explore further structural and tissue differences of the b1andb2 chain. This revealed glycosaminoglycan modi®cation a nd disul de- dependent dimerization of b1IV but not of b2IV, which could be readily ... exclude the possibility that they represent artefacts of the treatments used. Nevertheless, we also cannot dismiss the possibility of t he disul de -dependent dimeriza- tion of laminins in which domain...

Ngày tải lên: 21/02/2014, 03:20

... The sequences of PL and LPL are identical at 31% of their residues in the N-terminal domain (40% similarity) and are 28% identical in the C-terminal domain (38% similarity). The catalytic efficiency and ... in the C-terminal domain were made to address the functional roles of the C-terminal domain in heparin binding and in catalytic activity. We also provide experimental evidence of head-to-tail subunit ... N-terminal domain. Recently, however, several lines of evidence have demonstrated that the Correspondence to I. Inoue, Division of Genetic Diagnosis, Institute of Medical Science, The University of Tokyo,...

Ngày tải lên: 21/02/2014, 15:20

... monomer) and that both models place S1 and S2 on the same actin monomer. Where the present model differs is that we place S2 beside S1 on subdomain 1 of actin instead of on subdomain 2 and this requires ... France; 3 Genes and Development Group, Department of Biomedical Sciences, University of Edinburgh, Scotland It is generally assumed that of the six domains that comprise gelsolin, domain 2 is primarily ... quenching of the chromophore (K d ¼ 2 mM). Determination of the 159–193 peptide/actin interface Two approaches were used for identification of large fragments of actin to which gelsolin 159–193 peptide...

Ngày tải lên: 22/02/2014, 07:20

... University of Debrecen, Hungary; 3 Department of Inorganic Chemistry, and 4 Research Group for Antibiotics, Department of Chemistry, University of Debrecen, Hungary; 5 International Institute of Molecular ... Gyula Batta 4 and Jacek Kuz ´ nicki 1,5 1 Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, Warsaw, Poland; 2 Department of Biochemistry and Molecular ... the calcium-binding ligands are designated by their coordinates: x, y, z,-y, -x and -z [60]. Residues discussed in the text are given in bold (G34, K60 and G81 of CR I –II and G29, G66, R68, G71 and G74 of Calb I–II)....

Ngày tải lên: 22/02/2014, 07:20

... O() →0 . ENTROPY AND THE LOCALIZATION OF EIGENFUNCTIONS 449 • A i 2 = A i except on a set of measure of order h κ . • For i = j, A i A j = 0 except on a set of measure of order h κ . We must ... choices is bounded by l (1−τ)N+n 1 . Choose N 0 such that l n 1 ≤ e N 0 Λδ 50 . This ends the proof of Lemma 2.3.1. 468 NALINI ANANTHARAMAN Semi-classical symbols of order m and degree l (depending ... operators on L 2 (M) and denote A i (t) their evolutions under the quantum flow: A i (t) = exp  − it h∆ 2  ◦ A i ◦ exp  it h∆ 2  . We de ne the “measures” of cylinder sets under µ h , by the expressions: µ h  [α 0 ,...

Ngày tải lên: 06/03/2014, 08:21

... [12] and Gamide [13]. Although both Ggly and Gamide bind iron, only in the case of Ggly is biological activity dependent on ferric ion binding [12]; Gamide is fully active in the absence of metal ... homeostasis. Inde- pendent evidence for a connection between gastrins and iron status has been provided by a microarray comparison of gene expression profiles in the stomachs of gastrin -de cient and wild-type ... obviously essential to a full understanding of the interaction. The independent involvement of iron [17] and nonamidated gastrins such as Ggly [10] in the development of colorectal cancer make it...

Ngày tải lên: 07/03/2014, 02:20

... state of KH domains. Although several KH domains form ABC Fig. 10. Crystal structure of tandem type II KH domains of NusA in complex with RNA. The tandem KH1–KH2 domains of NusA recognize RNA ligand ... by tandem but independent KH domains – NMR structure of the KH3 and KH4 domains of FBP in complex with FUSE ssDNA FUSE-binding protein has four KH domains, which are separated by linkers of varying ... b-sheet composed of three antiparallel b-strands is abutted by three a-helices (a1, a2, and a¢). The b-sheet in type I KH domains consists of three b-strands in the order b1, b¢ and b2. The b1-strand and...

Ngày tải lên: 07/03/2014, 05:20

... stubbornly avoided purification and cloning, remaining elusive despite the efforts of a number of groups. Nevertheless, the information reported here adds consider- ably to our understanding of sialate ... patients we provide strong evidence suggesting that the level of O-acetylated sialic acids present in normal and diseased human colon may be dependent on the relative activities of OAT to lysosomal OAE. ... for Biomolecular Research, Department of Bio-Organic Chemistry, Section of Glycoscience and Biocatalysis, Utrecht University, the Netherlands A decrease in the level of O-acetylated sialic acids...

Ngày tải lên: 07/03/2014, 14:20

... utilization of reduced nucleotide coenzymes by Pyrococcus. The central metabolism of this organism uses an unusual NADPH-dependent sul de dehydrogenase which is capable of both the NADPH-dependent reduction ... NADPH-dependent reduction of elemental sulfur and the NADP + -dependent oxida- tion of ferredoxin [22]. A unique NADPH-dependent alcohol dehydrogenase with wide substrate specificity and a strong preference ... and thermoactivity of the CoADR phCoADR is stable for months at both )80 °C and )20 °C, and has half-lives of > 100 and 39 h at 85° and 95 °C, respectively. Figure 3 shows the dependence of...

Ngày tải lên: 07/03/2014, 17:20

... represen- tation of the relative densities of the free DNA measured at increasing concentrations of HbpR. The percentage of free DNA was calculated from densitometric measurements of the radiolabe- led bands ... DNA-binding site and by deletion of the effector domain David Tropel 1 * and Jan R. van der Meer 1,2 1 Process of Environmental Microbiology and Molecular Ecotoxicology, Swiss Federal Institute ... central Keywords Pseudomonas azelaica; r54-dependent transcriptional activators; XylR family Correspondence J. R. van der Meer, Department of Fundamental Microbiology, Batiment de Biologie, University of Lausanne,...

Ngày tải lên: 07/03/2014, 17:20

Ngày tải lên: 07/03/2014, 17:20

Ngày tải lên: 07/03/2014, 21:20

Ngày tải lên: 08/03/2014, 01:20

Ngày tải lên: 08/03/2014, 09:20