instructive astrocyte differentiation of nscs by signaling of bmps and il 6 type cytokines
Báo cáo y học: "Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages" pdf
Ngày tải lên :
11/08/2014, 08:22
... then stimulated by CSM (0.03, 0. 06 and 0.12 OD) for h RNA was extracted and mRNA levels of IL- 8 were quantified by real-time PCR (A) Results are expressed as copies of IL- 8 vs copies of GAPDH mRNA ... phosphorylation of and degradation of CSM regulates phosphorylation of IRAK IRAK in HEK cells CSM regulates phosphorylation of IRAK and degradation of IκB-α by MDMs and phosphorylation of IRAK in ... pathogenesis of COPD [6, 7] Multiple intracellular signaling events occur by CS, which ultimately leads to the synthesis and release of pro-inflammatory mediators, such as interlukine-8 (IL- 8), IL- 1β, and...
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Báo cáo Y học: The evolution of monomeric and oligomeric bc-type crystallins potx
Ngày tải lên :
24/03/2014, 04:21
... fold-different stabilities J Mol Biol 269 , 260 – 269 55 Wenk, M., Herbst, R., Hoeger, D., Kretschmar, M., Lubsen, N.H & Jaenicke, R (2000) Gamma-S-crystallin of bocine and 56 57 58 59 60 61 62 63 64 65 human ... Val55, Val68, and Ile92, and that of Val143, Leu1 56, and Ile181 Then the C-terminal extensions have also been suspected to have a role in the evolution of domain association, as suggested by the ... monomeric and dimeric prototypes for the respective families of c- and b-crystallins, and simply referred to as c -type or b -type crystallins, respectively Both monomeric c -type crystallin and the...
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Báo cáo y học: "α Impact of VIP and cAMP on the regulation of TNF-α and IL-10 production: implications for rheumatoid arthritis" pps
Ngày tải lên :
09/08/2014, 01:23
... upregulating IL- 10 First, we compared the effects of VIP, rolipram, and dibutyryl cAMP on the production of TNF-α and IL- 10 by monocytes Spontaneous production of IL- 10 and TNF-α by monocytes ... 569 1 ± 265 pg/ml (P = 0.027) and 4 968 ± 372 pg/ml (P = 0.025) at concentrations of 10 µM and 20 µM respectively (IC50 = µM), and by rolipram, the PDE IV inhibitor, from 69 63 ± 230 pg/ml to 268 5 ... augments production of IL- 10 by PMA/ionomycin-stimulated macrophages The lack of augmentation of IL- 10 production by VIP is suggested by a To investigate the role of VIP as a modulator of cytokine production...
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Báo cáo y học: " Glycine tomentella Hayata inhibits IL-1b and IL-6 production, inhibits MMP-9 activity, and enhances RAW264.7 macrophage clearance of apoptotic cells" docx
Ngày tải lên :
10/08/2014, 05:21
... range of GTH concentration for suppressing cytokines was relatively small The viability of RAW 264 .7 cells was affected at GTH concentration of 330 mg/ml While the effects of GTH on IL- 1b, IL- 6 and ... the expression of IL- 6 mRNA in a dose-dependent manner (data not shown) GTH inhibits the production of IL- 1b and IL- 6 RAW 264 .7 cells were incubated with GTH at 20, 40, 80 and 165 μg/ml for 24 ... later and the cytokines were analyzed by ELISA Consistent with the results that GTH treatment suppressed mRNA expression of proinflammatory cytokines by RT-PCR, the production of IL- 1b and IL- 6 were...
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Báo cáo y học: "Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines" ppsx
Ngày tải lên :
11/08/2014, 08:22
... K3/4; IL- 12p70, L3/4; IL- 13, A5 /6; IL- 17; B5 /6; I-TAC, C5 /6; KC, D5 /6; Leptin, E5 /6; LIX, F5 /6; Lymphotactin, G5 /6; MCP-1, H5 /6; M-CSF, I5 /6; MIG, J5 /6; MIP-1α, K5 /6; MIP-1γ, L5 /6; RANTES, A7/8; SDF-1, ... Ligand, J1/2; Fractalkine, K1/2; GCSF, L1/2; GM-CSF, A3/4; IFNγ, B3/4; IL- 1α, C3/4; Il- 1β, D3/4; IL- 2, E3/4; IL- 3, F3/4; IL- 4, G3/4; IL- 6, H3/4; IL- 9, I3/4; IL- 10, J3/4; IL- 12p40p70, K3/4; IL- 12p70, ... Journal of Inflammation 2009, 6: 2 http://www.journal-inflammation.com/content /6/ 1/2 Figure The effects of TMP on the growth and viability of RAW 264 The effects of TMP on the growth and viability of...
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the role of il-33 and il-17 family cytokines in periodontal disease
Ngày tải lên :
22/12/2014, 21:05
... levels of IL1 7A, IL- 17E, IL- 17F, IL- 17A/F, IL- 17A :IL- 17E ratio and age 199 Table 4-10: Comparison of gingival crevicular fluid levels of IL- 17A, IL1 7E, IL- 17F and IL- 17A/F between males and females ... levels of IL- 17A, IL- 17E, IL- 17F, IL- 17A/F and age 205 4.2.19 Relationship between saliva levels of IL- 17A, IL- 17E, IL- 17F, IL- 17A/F and gender 2 06 4.2.20 mRNA expression of IL- 17 ... cells 64 1.5.3 Role of IL- 10 in inflammation and infection 65 1.5.4 IL- 10 and periodontal disease 67 1 .6 IL- 33 68 1 .6. 1 Introduction 68 1 .6. 2 Molecular...
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Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx
Ngày tải lên :
07/03/2014, 12:20
... components of the prostanoid signaling network are targets of C-Raf signaling pathways Triggering of C-Raf signaling resulted in a dramatic Cox-2 and ERK-dependent increase in the synthesis and release ... (2001) Prostacyclin-dependent apoptosis mediated by PPAR delta J Biol Chem 2 76, 462 60– 462 67 Lim H & Dey SK (2002) A novel pathway of prostacyclin signaling- hanging out with nuclear receptors Endocrinology ... levels by prostacyclin (prostaglandin I2) J Biol Chem 254, 167 1– 167 6 28 Heasley LE, Thaler S, Nicks M, Price B, Skorecki K & Nemenoff RA (1997) Induction of cytosolic phospholipase A2 by oncogenic...
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Báo cáo khoa học: Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids docx
Ngày tải lên :
16/03/2014, 10:20
... alternation of the n -6 ⁄ n-3 compositional ratio in favor of n-3 PUFAs affects mammary development and differentiation The effect of an n -6 ⁄ n-3 ratio change on mammary gland development and differentiation ... stimulates Jak2 and Stat5 activation, and induces b-casein expression and gland differentiation This model indicates that induction of mammary differentiation by alternation of the n -6 ⁄ n-3 ratio ... IH (19 96) Influence of differentiation and cell kinetics in the susceptibility of the mammary gland to carcinogenesis Cancer Res 40, 267 7– 268 7 Russo J & Russo IH (1995) Hormonally induced differentiation: ...
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Báo cáo khoa học: Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases Retinoic acid-induced upregulation of substrate and proteinase ADAM10 during neuronal cell differentiation ppt
Ngày tải lên :
30/03/2014, 11:20
... Gamma-secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins Biochemistry 42, 66 64 66 73 Gu Y, Misonou H, ... transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10 J Immunol 172, 63 62 63 72 FEBS Journal 272 (2005) ... gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation J Biol Chem 279, 181 46 181 56 12 Li Q & Sudhof TC (2004) Cleavage of amyloid-beta precursor protein and amyloid-beta...
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Báo cáo Y học: Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid pdf
Ngày tải lên :
31/03/2014, 15:20
... induced differentiation of HL -60 into granulocytes (data not shown) DISCUSSION PAK is a member of the serine/threonine kinase family, which includes three types of isoform, PAK68, PAK65 and PAK62 ... the rate of differentiation of HL -60 cells induced with ATRA Induction of Rac and PAK HL -60 cells were treated with lM ATRA for a week, and Rac and PAK were assayed in both cytosol and membrane ... peptide (C-19) of PAK68 The arrows on the right side denote immuno-positive PAK68, PAK65 and PAK62 bands Lane MW contained molecular weight standard proteins undifferentiated HL -60 , and they increased...
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differentiation of brewing yeast strains by pyrolysis
Ngày tải lên :
12/06/2014, 11:18
... Haverkamp, J and Hileman, F D (1982) Pyrolysis Mass Spectrometry of Recent and Fossil Biomaterials Elsevier Morrison, K B and Sugget, A (1983) Yeast handling, petite mutants and lager Proceedings of the ... Candida species and strains by pyrolysis mass spectrometry and Fourier transform infrared spectroscopy J Clin Microbiol 36, 367 –374 Wightman, P., Quain, D E and Meaden, P G (19 96) Analysis of production ... BB27 Both PyMS and FT-IR also show these strains to be closely related Finally, Wightman et al (19 96) also showed similarities between BB12, BB13 and BB14, and between B3 and BB24, and also between...
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báo cáo hóa học: " Astrocyte production of the chemokine macrophage inflammatory protein-2 is inhibited by the spice principle curcumin at the level of gene transcription" pptx
Ngày tải lên :
19/06/2014, 22:20
... 1999, 67 :2590- 260 1 Pousset F, Cremona S, Dantzer R, Kelley KW, Parnet P: IL- 10 and IL- 4 regulate type- I and type- II IL- 1 receptors expression on IL- 1 beta-activated mouse primary astrocytes J Neurochem ... NFκB and NF -IL- 6 cis-acting elements demonstrate that inhibition of MIP-2 by curcumin occurs at the level of gene transcription The importance of either of these elements in the regulation of inducible ... down-regulation of IkappaB kinase and NFkappaB activation in macrophages Biochem Pharmacol 2000, 60 : 166 5- 167 6 Das R, Mahabeleshwar GH, Kundu GC: Osteopontin stimulates cell motility and nuclear factor...
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Báo cáo y học: "Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer" pps
Ngày tải lên :
09/08/2014, 14:22
... collagen type in cartilage, and CS4, one of the monomers of the polysaccharide portion of proteoglycan, showed significantly enhanced production of these cartilage matrix proteins at days 10 and 21 of ... value of 60 .6 ± 14.5 μm2 in the center and 57.3 ± 12.4 μm2 the periphery of the Ad.GFP transduced aggregates, which showed no lacunae formation, of 541.3 ± 166 .3 μm2 in the center and 3 86. 1 ± ... proteins (BMPs) , members of the TGF-β superfamily BMPs are a group of secreted polypeptides with pleiotropic roles in many different cell types and were originally identified by their ability to...
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Báo cáo y học: "Antimelanogenic effect of c-phycocyanin through modulation of tyrosinase expression by upregulation of ERK and downregulation of p38 MAPK signaling pathway" docx
Ngày tải lên :
10/08/2014, 10:20
... Results Effects of Cpc on cell viability tyrosinase activity, and melanin production Figure 1A shows the viability of B16F10 melanoma cells after treating with Cpc The viability of melanoma cells ... dose-dependently reduced from 75.7% to 65 .7%, and 56. 2% to 47.5%, respectively, with Cpc concentration Figure Effect of Cpc on viability of B16F10 melanoma cell, tyrosinase activity and melanin contents Cells ... effects of Cpc on p38 MAPK and CREB signaling Figure 4A depicts the down-regulatory effect of Cpc on the activation of CREB The expression of p-CREB was markedly decreased at 30 and 60 after...
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Augmentation and differentiation of hematopoietic progenitor cells by CD137
Ngày tải lên :
11/09/2015, 14:34
... of proinflammatory cytokines (TNF, IL- 6, IL- 8 and IL- 12) and activation markers (ICAM-1) Concurrently, it inhibits the expression of anti-inflammatory cytokines (IL- 10) and differentiation markers ... al., 2002) Crosslinking of CD137L on DCs enhances the expression of CD11c, CD80, CD 86, MHC class II, and CCR7, and induces cellular adherence and the release of IL- 6, IL- 12, and TNF(Kim et al., ... Maturation, induction of CD11c, CD 86, CD137L, In vitro Laderach et al., 2003; MHC-II, IL- 12, and cellular adherence Kim et al., 2002 Mouse Induction of IL- 6, IL- 12, CD80 and CD 86 In vitro Futagawa...
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Analysis of gonad differentiation in zebrafish by histology and transgenics
Ngày tải lên :
14/09/2015, 09:39
... Expression of amh:tdTomato and bioinformatic analysis of amh promoter 46 3 .6. 2 Molecular cloning and characterization of cyp11b and creation of cyp11b:tdTomato transgenic line 48 3 .6. 2.1 Zebrafish ... mechanism and the early differentiation of ovary are not the main purpose of this study This study will contribute to the zebrafish-related research by providing a detailed view of gonadal differentiation ... ANALYSIS OF GONAD DIFFERENTIATION IN ZEBRAFISH BY HISTOLOGY AND TRANSGENICS WANG XINGANG (B Sc., Ocean University of Qingdao, China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY...
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Báo cáo y học: " Differentiation of convulsive syncope from epilepsy with an implantable loop recorder Khalil Kanjwal, Beverly Karabin, Yousuf Kanjwal, Blair P Grubb"
Ngày tải lên :
26/10/2012, 09:53
... conflict of interest exists References Hauser WA, Kurland LT The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1 967 Epilepsia 1975; 16( 1):1 -66 Hauser WA, Hesdorffer DC Epilepsy, ... Medical assessment and treatment of chronic epilepsy BMJ 1991; 302: 363 – 10 Chadwick D Epilepsy J Neurol Neurosurg Psychiatry 1994;57: 264 – 77 11 Kapoor WN Evaluation and outcome of patients with ... sudden episodes of profound hypotension and bradycardia resulting in loss of consciousness and, on occasion, convulsive activity (11-12) Linzer et al (6) reported that upto 12% of blood donors...
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ENHANCING THE EFFICIENCY OF THE QUALITY MANAGAMENT SYSTEM BY IMPROVING MANAGEMENT RESPONSIBILITY AND HUMAN RESOURCE MANAGEMENT AT VIET A PLASTIC AND COMPOSITE COMPANY
Ngày tải lên :
18/04/2013, 17:09
... 5810. 561 69 41.472 7205 .65 4 Total cost 299919.442 37407.752 40945.722 Profit before tax 8.458 9.748 10.078 Profit after tax 6. 162 6. 859 7.400 The business result shows that the revenue and profit of ... system of Viet A plastic and composite company in terms of management responsibility and human resource management Viet A plastic and composite company, a company of designing, manufacturing and ... especially in term of Website: http://www.docs.vn Email : lienhe@docs.vn Tel : 0918.775. 368 Website: http://www.docs.vn Email : lienhe@docs.vn Tel : 0918.775. 368 management responsibility and human...
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Removal of arsenic from synthetic groundwater by adsorption using the combination of laterite and ironmodified activated carbon
Ngày tải lên :
05/09/2013, 09:38
... AC, LA, and AC-Fe and Figure illustrates the comparison of LA-AC and LA-AC-Fe These figures indicated that the combination of LA and AC-Fe is the most feasible - 50 - Journal of Water and Environment ... (Brunauer, Emmett and Teller) surface area is 70.19m²/g, pore volume of 0.00 062 cm3/g and pore size of 1 26 Preparation of AC-Fe AC from coconut shell was taken from MAPECOH, Inc (Philippines) with ... stock solutions of As(III) were prepared from As(III) standard solution of 1003mg/L (Wako Pure Chemicals Ltd, Japan) The stock solutions of As(V) were prepared by dissolving 4. 164 6mg of Na2HAsO4.7H2O...
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ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED SECONDARY SCHOOL, NAM DINH CITY
Ngày tải lên :
07/09/2013, 13:19
... adverbs of manner? I.1.2 Formation of adverbs of manner I.1.3 Position of adverbs of manner 11 I.1.4 Classification of adverbs of manner 13 I.1.5 The differing functions of adverbs of manner and ... more than one kind of adverb in a sentence ( adverb of manner, adverb of place and adverb of time), adverb of manner precedes adverb of place and adverb of time So the order of these adverbs is ... error and a mistake An error is the result of lack of knowledge; i.e failure of competence, while a mistake is the learner’s failure of performance EA should be restricted to the study of errors...
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