importance of functional process zone over clinal position

... analysis of a purified GPI-anchorless soluble version of the mutant protein The Kcat ⁄ Km value of the mutant TNSALP was less than one-tenth of the Kcat ⁄ Km value of the soluble form of the wild-type ... efficient catalytic function of TNSALP In support of our hypothesis, the cysteine residue at position 433 in one subunit of TNSALP (R433C) becomes crosslinked to the counterpart of the other subunit ... 1), indicating that the conversion of valine to alanine at position 406 in the crown domain compromises the catalytic function of TNSALP Protease sensitivity of TNSALP (V406A) As shown in Fig...

Ngày tải lên: 07/03/2014, 05:20

... for a prolongation of clot lysis time proportional to the increase in T1 ⁄ of activity of the mutant The YQ mutant was also used to demonstrate the importance of CPU stability over proCPU concentration ... instructions Expression of mutant proCPUs in insect cells Determination of the half-life (T1/2) of CPU’s activity The T1 ⁄ of the activity of the best mutants secreted in the supernatant of the cells in ... CPU, might be of importance for the 780 process of CPU’s activity destabilization When we changed these two amino acids to their counterpart in porcine CPB (I204Y ⁄ I205E), the T1 ⁄ of the mutants’...

Ngày tải lên: 07/03/2014, 12:20

... function of these transporters Importance of conserved motif for FhaC function The complete deletion of L6 in FhaC has been shown to abolish the secretion of FHA, indicating the importance of this ... initial recruitment of FHA in the periplasm Structure of FhaCR450A In order to test whether R450 is essential for the structural integrity of FhaC, e.g for the position of functionally important ... Comparison of the electrophysiological behaviour of FhaCR450A (grey) and FhaCY452A (black) with superposition of the I ⁄ V curves in (a) and of the amplitude histograms in (b) The perturbed behaviour of...

Ngày tải lên: 23/03/2014, 03:20

... measure of the overall state of walking function Additional indices such as the temporal symmetry ratio between paretic and non-paretic limbs can also offer further insight regarding the nature of ... period of walking in individuals after stroke We hypothesized that participants would demonstrate a progressive slowing of gait speed over the period of the test and an increased expression of gait ... standard levels of clinically meaningful change However, participants who rested progressed from moderate to severe levels of asymmetry over the six minutes [9] The functional implications of severe...

Ngày tải lên: 19/06/2014, 08:20

... Source of candidate genes for water holding capacity of pork………… 1.3 The functions of candidate genes involve the mechanism of ubiquitination/deubiquitination processes……………………………… 1.4 Aims of the ... Aims of the current study The objective of the study was to evaluate the effects of functional candidate genes on meat quality by the identification of polymorphisms in transcribed regions of these ... function of UBE3B results in the decreased of water holding capacity of pork 3.2.4 The analysis of ZRANB1 The OTU (ovarian tumor) domain of ZRANB1 removes ubiquitin signals from a major component of...

Ngày tải lên: 19/11/2015, 16:33

... concept of diasporic spaces and diasporic spaces of migrants in Singapore The fundamental significance offered to the meanings of “spaces” in the study of migration and diaspora has often centered ... existing researchers on the functional importance of diasporic spaces 1.4 Methodology For the purpose of this survey, I have chosen to adopt the qualitative method of semi-structured interviewing ... 1.2 Objectives of thesis The initial goal of this thesis is to investigate how Malaysian Chinese in Singapore construct their identity and perceive of the values and ways of life of Singaporeans...

Ngày tải lên: 26/11/2015, 12:23

... our sample profile and that of both fast food restaurant profiles gives us a reasonable ground to conclude that our sample profile is a representative of the actual customer profile of both fast ... profile, when compared with the customer profile sample of both fast food restaurants, one check was carried out Our respondent’s demographic profile was compared with the customer profile of ... students of BTH who are customers of both restaurants We decided to use the student of BTH because from the customer profile of MacDonald and Max hamburger, customers between the age of 18 and...

Ngày tải lên: 24/09/2012, 17:19

... affect outcomes of RRT review and represent an important component of dose Studies of RRSs that not deliver an adequate dose in terms of frequency of intervention and team composition are likely ... exceeded the rate of MET review [22] Put simply, if the MET is a major method of prevention of SAEs on the ward, the rates of MET review should be similar to, if not greater than, rates of SAEs Available ... important element of ‘dose’ might well include not only the number of attendances but the composition of the team It is clinically plausible that a MET will deliver more Page of (page number not...

Ngày tải lên: 25/10/2012, 10:06

... prevalence of gout in the USA ranges between 0.5–2.8% in men and 0.1–0.6% in women [2] The prevalence rises to 4.4% of men and 1.8% of women over the age of 65 [4] A two-fold increase in incidence of ... the continuous aging of the population as well as the widespread use of diuretics for treatment of hypertension [4] Gout is a clinical syndrome caused by the deposition of monosodium urate monohydrate ... case of an isolated attack of gout in the wrist Acute onset of polyarticular gouty arthritis is more frequently seen in older patients most of whom are receiving diuretics for the management of...

Ngày tải lên: 25/10/2012, 10:06

... western medicine practitioner and self perceived level of health and possession of western or Chinese medicine insurance coverage patterns of OTC and medical service use as dependent variables ... http://www.cmjournal.org/content/5/1/41 Author details School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong, China 2School of Pharmacy, The Chinese University of Hong Kong, Shatin, Hong ... terms of gender, age, education level, self reported health status, chronic disease status, smoking, drinking, exercise habit, possession of Chinese and/or western medicine insurance coverage,...

Ngày tải lên: 25/10/2012, 10:06

... age of ten in group NA than in group A This proportion increased from 68.3% at the age of three to 87.3% at the age of ten for group NA, and from 62.5% at the age of three to 66.7 at the age of ... study At the age of seven, all of them still living in the region were included in a follow-up of their computerised medical records, which were examined for the occurrence of the diagnosis asthma ... obtained by investigations of the maternal medical records at the University Hospital, including PHC data of the statements made by the mid-wife in her records of the check-up of the mothers during...

Ngày tải lên: 26/10/2012, 09:48

... surface profile with conditions of Exp-2…………….79 Figure 6.11 Steady water surface profile with conditions of Exp-5…………….80 Figure 6.12 Steady water surface profile with conditions of Exp-6…………….80 ... plot of water surface in 2D simulation of Exp-1 …………….95 Figure 6.35 Carpet plot of water surface in 2D simulation of Exp-2…………… 95 Figure 6.36 Carpet plot of water surface in 2D simulation of ... plot of water surface in 2D simulation of Exp-4…………… 96 Figure 6.38 Carpet plot of water surface in 2D simulation of Exp-5…………… 97 Figure 6.39 Carpet plot of water surface in 2D simulation of Exp-6……………...

Ngày tải lên: 06/11/2012, 10:35

... populated countries of the world, with a population of about 129 million in 2001(Bangladesh Bureau of Statistics, 2002) Dhaka is the capital city of Bangladesh, and Bauniabad is one of the urban poor ... 80% of 5-day biochemical oxygen demand (BOD5) and nearly 80% of chemical oxygen demand in potassium dichromate method (CODCr) Though still the concentrations of BOD5 and CODCr of the effluent of ... to treat human waste of about 100 households’ members, it is presumed that more than twice of human waste is flowing per biogas plant because of the growth of the number of the people living...

Ngày tải lên: 05/09/2013, 09:08

... that there is a strong link between the amount of eye contact people receive and their degree of participation in group communication in the number of turns taken in a group conversation for example ... fundamentally, time and effort saving Much of the above is likely to seem transparently obvious, only natural, and an aspect of human behaviour either innate or developed over time But watch yourself, watch ... effort with specific messages delivered by eye and facial expression Show praise, encouragement often, and disapproval occasionally Remind learners that they ought to know an answer or that they...

Ngày tải lên: 06/09/2013, 10:10

... of Americans not believe it takes a lot of money for a woman to make a good impression at work Two-thirds (65%) of Americans not believe it takes a lot of money for a woman to have the kind of ... job well More than half (59%) of Americans believe a ppeara nce is a fa ctor, while 36% b elieve ap pearan ce is not a factor Five percen t of Ame ricans are not sure of any if the s tateme nts ... Other (Specify) 0% None of the above (DO NOT READ) 4% Don’t know/Not sure (DO NOT READ) 3% Do you think it takes a lot of money for a woman to have the kind of clothes, hair and makeup...

Ngày tải lên: 18/10/2013, 14:15

Ngày tải lên: 22/12/2013, 22:17

... to promote good-will and harmony among the people It is therefore important to know the policy of the newspaper that one reads In general, however, the newspaper tries to report as accurately...

Ngày tải lên: 22/12/2013, 22:17

... of temperature gives a unit energy, that of pressure gives a unit mass and that of concentration delivers an impulse of component mass to a process system, TLFeBook 2.1 Signals 11 • impulse of ... special group of information with major importance is the one that gives the current state of the system The state of a system is the collection of all TLFeBook 18 Basic Notions of Systems and ... problems of relatively low dimensionality The successful establishment of the state -of- art in nonlinear process systems control in a concise textbook represents a laudable contribution to process...

Ngày tải lên: 01/01/2014, 18:38

Ngày tải lên: 16/01/2014, 21:20